Case Western Reserve University StrokeNet Regional Coordinating Center

凯斯西储大学 StrokeNet 区域协调中心

• 批准号: 10460337
• 负责人: SOPHIA SUNDARARAJAN
• 金额: $ 30.57万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-15 至 2023-12-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10460337
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Adult; Air; Award; Biotechnology; Caring; Child; Clinic; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Clinical Trials Unit; Collaborations; Communities; Country; County Hospitals; Critical Care; Data; Engineering; Enrollment; Ensure; Ethnic Origin; Fostering; Funding; Grant; Great Lakes Region; Healthcare Systems; Hospitals; Image; Individual; International; Intervention; Lead; Leadership; Medical center; Mentors; Mentorship; Michigan; Monitor; Neurology; Nurses; Participant; Physicians; Population; Positioning Attribute; Prevention; Race; Recording of previous events; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Role; Route; Running; Rural; Scientist; Site; Stroke; Structure; System; Training; Translational Research; Transportation; United States Department of Veterans Affairs; United States National Institutes of Health; Universities; University Hospitals; Urban Community; West Virginia; Work; acute care; acute stroke; functional electrical stimulation; neurosurgery; novel therapeutics; organizational structure; patient population; programs; screening; sex; stroke clinical trials; stroke patient; stroke trials; study population

Cleveland is an urban community with several healthcare systems, internationally renowned researchers and a rich history of cooperation with respect to stroke care. University Hospitals of Cleveland (University Hospitals), The Cleveland Clinic, MetroHealth and the Louis Stokes Cleveland VA Medical Center (Cleveland VA) are affliated with Case Western Reserve University (CWRU) and collaborate in a Clinical Translational Science Collaborative (CTSC- funded by a CTSA) to enhance training, research, and discovery in Cleveland. In 2013 we were awarded a Regional Coordinating Center (RCC) as part of NIH StrokeNet. This application is to to renew that grant. We have expanded our RCC adding sites in Toledo (Mercy St Vincent Medical Center or Mercy St Vincent), Columbus (OhioHealth), Grand Rapids, Michigan (SpectrumHealth) and Morgantown, WV (West Virginial University (WVU). The inclusion of one county hospital with a large emergency department, VA hospital, and two urban academic medical centers, one academic medical center in a rural state ensures a diverse patient and study population. Our RCC has excellent participation and quality metrics on StrokeNet studies, including the highest enrollment in StrokeNet study in the Great Lakes Region. We have a diverse research community, with clinical researchers, basic scientists, engineers and biotech companies, to collaborate with and bring new projects to the network. We have large hospitals systems, including 3 hospitals ranked in the top 50 Neurology and Neurosurgery programs in the country, 6 Comprehensive Stroke Centers and a seventh site that will be reviewed for Comprehensive designation in October 2017. We have state of the art transportation resources including critical care air transport with physicians and nurse practicioners on board and 2 hospital systems with mobile stroke units that administer thrombolytics in the field or en route to the hospital. We have special expertise in penumbral imaging, acute endovascular therapy and rehabilitation and functional electrical stimulation. We propose a multi-teired leadership. Dr Sophia Sundararajan and Dr. Ken Uchino will lead the RCC as PIs, and representatives from each of the eight hospitals will serve on the Executive committee with the PIs, as will a Project Manager and Training Director. The Executive Committee includes senior and more junior investigators and will oversee and run all aspects of the RCC, but also provide mentorship for more junior investigators. Our leadership succession plan has already successfully mentored Drs Sundararajan and Uchino who will assume the Co-PI roles of this application. With the expertise and resources detailed in this application, the Case Western Reserve University RCC will be well positioned to enhance the structure and organization of our RCC and further accelerate participation in clinical trials for stroke acute intervention, prevention and rehabilitation in both adults and children.

克利夫兰是一个城市社区，拥有多个医疗保健系统，国际知名的研究人员 以及关于中风护理的丰富合作历史。克利夫兰大学医院（大学 医院），克利夫兰诊所，Metrohealth和Louis Stokes Cleveland VA医疗中心 （克利夫兰弗吉尼亚州）与凯斯西部储备大学（CWRU）折磨并在临床上合作 转化科学合作社（由CTSA资助），以增强培训，研究和 在克利夫兰的发现。 2013年，我们被授予了NIH的一部分区域协调中心（RCC） Strokenet。此申请是要续签这项赠款。我们已经扩展了托莱多的RCC添加站点 （Mercy St Vincent Medical Center或Mercy St Vincent），哥伦布（俄亥俄州健康），密歇根州大急流城 （SpectrumHealth）和西弗吉尼亚州摩根镇（西维尼元大学（WVU）。包含一个县 医院拥有大型急诊科，VA医院和两个城市学术医疗中心，一个 农村国家的学术医疗中心可确保多元化的患者和研究人群。 我们的RCC在跨语研究中具有出色的参与和质量指标，包括最高的 在大湖地区的Strokenet研究入学。我们有一个多元化的研究社区， 临床研究人员，基础科学家，工程师和生物技术公司，与合作并带来新的 项目到网络。我们有大型医院系统，其中包括3家在前50名中排名的医院 该国的神经和神经外科计划，6个综合中心和第七名 这将在2017年10月进行审查以供全面指定。 运输资源，包括与医生和护士从业人员一起运输的关注护理航空运输 和2个带有移动冲程单元的医院系统，可以在现场管理血栓分析或前往 医院。我们在半半成像，急性血管内治疗和康复方面有特殊的专业知识 和功能电刺激。我们提出了一个多学业的领导。索菲亚·桑达拉扬（Sophia Sundararajan）博士和博士 肯·乌奇诺（Ken Uchino PIS执行委员会，项目经理和培训总监也是如此。高管 委员会包括高级和更多的初级调查人员，并将监督RCC的各个方面， 但也为更多的初级调查人员提供指导。我们的领导继承计划已经 成功指导了Sundararajan和Uchino博士，他们将担任该应用程序的共同角色。 凭借本应用程序中详细介绍的专业知识和资源，西部储备大学RCC将 可以很好地提高我们的RCC的结构和组织，并进一步加速参与 在成人和儿童的中风急性干预，预防和康复的临床试验中。