Opioid Use Disorder among Criminal Justice-Involved Women: Integrating Trauma-Informed and Gender-Specific Care with Medication-Assisted Treatment

项目概要 与阿片类药物过量相关的死亡和监禁率急剧上升， 女性受到的影响尤为严重。尽管物质使用障碍的负担较高 与参与刑事司法 (CJI) 的男性相比，CJI 女性感染艾滋病毒/艾滋病的可能性较小 获得药物滥用和艾滋病毒治疗。拟议的干预措施将联系并保留 最近在药物辅助治疗 (MAT) 计划中患有 CJI 的女性，识别并联系 为妇女提供必要的社会服务，并为妇女提供阿片类药物过量反应 培训。具体来说，候选人的目标是 1) 对 CJI 女性、MAT 进行深入访谈 提供者和刑事司法专业人员确定非法阿片类药物使用的促进因素和障碍 CJI 妇女停止和减少艾滋病毒危险行为以及遭受暴力的情况； 2） 制定针对特定性别和创伤的干预措施，利用同伴导航来 将 CJI 妇女与 OUD 联系到 MAT 计划、必要的健康和社会服务，以及 提供阿片类药物过量反应培训； 3) 进行试点研究（随机对照 试验）来评估性别特定和创伤知情的组成部分是否充分 使用 50 名社区招募的 CJI 女性样本共同进行干预功能，这些女性使用 非法阿片类药物。为了完成拟议的研究任务，候选人已撰写 由国际知名学者担任导师的团队。通过这个提议的K01， 候选人将扩大她的工作范围，以治疗阿片类药物使用障碍和常见疾病 合并症。本提案中概述的研究和培训将使候选人获得 导致 CJI 女性预后不佳的社会因素的内容专业知识 OUD，物质使用和 CJI 女性的创伤，同时发展她 实施和评估临床试验的技能。候选人的长期职业目标是 制定基于证据的干预措施，以减少物质使用及其同时发生的健康和 边缘化和弱势群体的社会后果。拟议的工作 通过使她能够设计、实施、 并评估为 CJI 女性设计的试点干预措施。

Project Summary Opioid-related overdose deaths and incarceration rates have skyrocketed and have disproportionately affected women. Despite having a higher burden of substance use disorders and HIV/AIDS than criminal justice-involved (CJI) men, CJI women are less likely to have access to substance use and HIV treatment. The proposed intervention will link and retain women with recent CJI in medication-assisted treatment (MAT) programs, identify and connect women with necessary social services, and provide women with opioid overdose response training. Specifically, the candidate aims to 1) conduct in-depth interviews with CJI women, MAT providers, and criminal justice professionals to identify facilitators and barriers to illicit opioid use cessation and decreases in HIV risk behaviors and exposure to violence among CJI women; 2) develop a gender-specific and trauma-informed intervention that utilizes peer navigation to connect CJI women with OUD to MAT programs, necessary health and social services, and provides opioid overdose response training; and 3) conduct a pilot study (randomized control trial) to assess the adequacy in which components of the gender-specific and trauma-informed intervention function together using a sample of 50 community-recruited CJI women who use opioids illicitly. In order to complete the proposed research tasks, the candidate has composed a team of internationally recognized scholars as mentors. Through this proposed K01, the candidate will expand the breadth of her work to treatment for opioid use disorders and common comorbidities. The research and training outlined in this proposal will allow the candidate to gain content expertise on social factors that lead to sub-optimal outcomes among CJI women with OUD, trauma among substance-using and CJI women, while simultaneously developing her skills in implementing and evaluating clinical trials. The candidate’s long-term career goal is to develop evidence-based interventions to reduce substance use and its co-occurring health and social consequences among marginalized and vulnerable communities. The proposed work helps her make further strides to accomplishing this goal by enabling her to design, implement, and evaluate a pilot intervention designed for CJI women.