2022 Endothelial Cell Phenotypes GRC and GRS

项目摘要 本次戈登研究会议(GRC)题为《健康和疾病中的内皮细胞表型》，以及 与戈登同名的研究研讨会(GRS，由学员组织并为学员举办)有 更好地了解不同的内皮细胞表型和功能是潜在的假设 不同的组织环境是重要的基础知识，这些知识对于合适的血管是至关重要的 修复和组织再生。目标是弥合现有的知识和沟通差距 各级研究人员(学生、博士后、学术界和工业界的初级和高级科学家) 内皮细胞生物学和异质性，以及研究血管疾病、生物成像和组织的人 工程学和再生医学。这些领域最近开发了范例、工具和模型来 有助于实现这一目标，预计这种集成将推动所有领域朝着及时翻译BASIC 发现。GRC将有力地促进NIH之间持久的跨学科互动和合作- 资助和国际血管和干细胞生物学家，学术和行业科学家之间，以及 通过接触新的想法、问题和知识，在这些领域的交叉领域培养下一批科学家 机遇。相关的全球资源报告也将支持这些目标，重点是学员的发展。 全球资源中心主席和副主席是该领域的领导者，非常适合组织这次会议。这次会议 目标将通过将一组选定的研究人员(约150名参与者)聚集在一起 小而半孤立的地点(西班牙巴塞罗那附近)，为期一周，在旨在 在展示大部分未公布的数据后促进广泛讨论，并促进非正式互动 以及通过分享午餐和下午的社交活动建立网络，这对受训人员特别有利。受邀 演讲者是根据研究、主题和与学员接触的意愿来选择的。参与者 将根据主题和人口统计数据进行选择。女性和少数族裔演讲者被邀请，那些 将鼓励团体申请成为参与者。将由受训人员组织一次GRS预会， 受训者(将参加GRS的GRC主席和教师导师的投入有限)，以及 介绍受训人员的工作，以促进这一群体之间的联系，并为他们提供一个同行小组，如 他们过渡到更大的会议。这次GRC/GRS会议将对 因为它在一个有利的时机解决了血管生物学中的重要基本问题和健康问题。

Project Summary This Gordon Research Conference (GRC), “Endothelial Cell Phenotypes in Health and Disease”, and the accompanying Gordon Research Seminar (GRS, organized by and for trainees) of the same name have the underlying hypothesis that a better understanding of differential endothelial cell phenotypes and functions is distinct tissue environments is important basic knowledge, and this knowledge is crucial for proper vascular repair and tissue regeneration. The goals are to bridge existing knowledge and communication gaps between researchers at all levels (students, postdocs, junior and senior scientists in academia and industry) who study endothelial cell biology and heterogeneity, and those who study vascular disease, bioimaging, and tissue engineering and regenerative medicine. These fields have recently developed paradigms, tools and models to aid this goal, and this integration is predicted to move all fields forward towards timely translation of basic discoveries. This GRC will strongly foster lasting interdisciplinary interactions and collaborations amongst NIH- funded and international vascular and stem cell biologists, between academic and industry scientists, and develop the next cadre of scientists at the intersection of these fields by exposure to new ideas, issues and opportunities. The associated GRS will also support these goals with an emphasis on trainee development. The GRC Chair and vice-Chair are leaders in the field and well-suited to organize the meeting. The meeting goals will be accomplished by bringing together a selected group of researchers (about 150 participants) to a small, semi-isolated site (near Barcelona, Spain) for a week, in a venue and meeting structure designed to foster extensive discussion after presentation of largely unpublished data, and to promote informal interactions and networking through shared meals and afternoon social activities that especially benefit trainees. Invited speakers are chosen based on excellence in research, topic, and willingness to engage trainees. Participants will be chosen based on topic and demographics. Female and minority speakers have been invited, and those groups will be encouraged to apply as participants. A GRS pre-meeting will be organized by trainees and for trainees (with limited input from GRC chairs and faculty mentors that will attend the GRS), and feature presentation of trainee work, to facilitate networking among this group and provide them with a peer group as they transition into the larger meeting. This GRC/GRS meeting will have a strong and lasting impact on the field, as it addresses important basic questions and health issues in vascular biology at a propitious time.