Administrative Core

抽象行政核心 高级临床和转化研究(Advance-CTR)的目标是弥合 通过发展多机构的临床转化性研究，在临床和基础科学界 对罗德岛的临床实践和保健政策产生有利影响的基础设施。我们会 利用罗德岛州的教育机构、简化的临床环境和IDEA赞助 研究指导计划和最先进的研究基础设施，以增强临床翻译 通过支持所需的研究、培训、管理、监督和协调过程进行研究 改变我们参与机构的临床和转化性研究环境。这个 行政核心负责领导和管理结构，以有效管理， 协调和监督先期CTR。领导结构建立在 机构间高影响力奖项的许多例子表明了合作 已经收到，并支持这一想法-CTR。该结构通过跨 全州范围内的大学、医院、政府机构、非营利组织、行业合作伙伴和 卫生部将对罗德岛人的健康产生影响。在布朗大学内部，Advance-CTR 合作范围涉及生物和医学部、阿尔伯特医学院、该计划 在生物学方面，公共卫生学院、工程学院和其他研究所和中心。在 在罗德岛大学，我们影响了药学、护理和环境与生命科学学院。 通过与罗德岛质量研究所的战略伙伴关系和获得All Payor索赔 数据库，我们能够通过真正以人口为基础的方式评估所有罗德岛人的医疗保健 流行病学研究、人群表型和临床调查。这一想法-CTR提案具有 以下具体目标：1)提供组织结构、领导、治理和咨询支持 开发、维护和增强支持临床和翻译的高级CTR核心活动 研究。2)支持战略计划的开发、协调和实施，并管理 确保高效运营所必需的业务、财务、沟通和评估职能 促进增长和Advance-CTR的长期可持续性。3)作为开发书面材料的来源 有效的组织治理和长期可持续性所需的政策和程序 先进的CTR和临床研究人员的留用。

ABSTRACT - ADMINISTRATIVE CORE The goal of Advance Clinical and Translational Research (Advance-CTR) is to bridge the gaps between the worlds of clinical and basic science by developing a multi-institutional, clinical translational research infrastructure that beneficially impacts clinical practice and health care policy in Rhode Island. We will leverage Rhode Island’s educational institutions, streamlined clinical environment, and IDeA sponsored research mentoring programs and state of the art research infrastructure to enhance clinical translational research by supporting the research, training, management, oversight, and coordination processes needed to transform the clinical and translational research environment in our participating institutions. The Administrative Core is responsible for the leadership and management structure for effectively managing, coordinating and supervising the Advance-CTR. The leadership structure builds upon the Culture of Collaboration demonstrated by the numerous examples of inter-institutional high impact awards that have been received and that support this IDeA-CTR. The structure ensures representation by working across a statewide consortium of universities, hospitals, government agencies, non- profits, industry partners, and the Departments of Health to impact the health of Rhode Islanders. Within Brown University, Advance-CTR collaborations extend across the Division of Biology and Medicine, the Alpert Medical School, the Program in Biology, the School of Public Health, the School of Engineering, and other Institutes and Centers. At the University of Rhode Island, we impact the Colleges of Pharmacy, Nursing, and Environment & Life Sciences. Through strategic partnerships with the Rhode Island Quality Institute and access to the All Payor Claims Database, we are able to evaluate the health care of all of Rhode Islanders through truly population based epidemiological studies, population phenotyping and clinical surveys. This IDeA-CTR proposal has the following Specific Aims: 1) Provide the organizational structure, leadership, governance, and advisory support to develop, maintain, and enhance Advance-CTR Core activities in support of clinical and translational research. 2) Enable the development, coordination, and implementation of strategic initiatives and manage the business, financial, communication, and evaluation functions necessary to ensure efficient operations and to foster growth and the long-term sustainability of Advance-CTR. 3) Serve as a source for developing written policies and procedures necessary for effective organization governance and long-term sustainability of Advance-CTR and retention of clinical research investigators.