Administrative Core

摘要-行政核心 高级临床和转化研究（Advance-CTR）的目标是弥合 通过发展多机构临床转化研究，进入临床和基础科学世界 基础设施，有益地影响临床实践和医疗保健政策在罗得岛。我们将 利用罗得岛的教育机构、精简的临床环境和IDEA赞助的 研究指导计划和最先进的研究基础设施，以提高临床转化 通过支持所需的研究、培训、管理、监督和协调过程来进行研究 改变我们参与机构的临床和转化研究环境。的 行政核心负责领导和管理结构的有效管理， 协调和监督Advance-CTR。领导结构建立在文化的基础上， 机构间高影响力奖项的众多例子表明了合作， 并支持本IDEA-CTR。该结构通过跨 全州范围内的大学、医院、政府机构、非营利组织、行业合作伙伴， 卫生部影响罗德岛人的健康。布朗大学Advance-CTR 合作延伸到生物学和医学部，阿尔珀特医学院，该计划 在生物学，公共卫生学院，工程学院，和其他研究所和中心。在 罗得岛大学，我们影响药学院，护理学院，环境与生命科学学院。 通过与罗得岛质量研究所的战略合作伙伴关系，并访问所有付款人索赔 数据库，我们能够通过真正的人口基础评估所有罗德岛人的医疗保健 流行病学研究、人口表型分析和临床调查。该IDEA-CTR提案具有以下特点： 具体目标如下：1）提供组织结构、领导、治理和咨询支持 开发、维护和加强Advance-CTR核心活动，以支持临床和翻译 research. 2)促进战略计划的制定、协调和实施，并管理 业务、财务、沟通和评估职能，以确保有效运营， 促进Advance-CTR的增长和长期可持续性。3)作为开发书面 有效的组织治理和长期可持续性所需的政策和程序 推进CTR和留住临床研究者。

ABSTRACT - ADMINISTRATIVE CORE The goal of Advance Clinical and Translational Research (Advance-CTR) is to bridge the gaps between the worlds of clinical and basic science by developing a multi-institutional, clinical translational research infrastructure that beneficially impacts clinical practice and health care policy in Rhode Island. We will leverage Rhode Island’s educational institutions, streamlined clinical environment, and IDeA sponsored research mentoring programs and state of the art research infrastructure to enhance clinical translational research by supporting the research, training, management, oversight, and coordination processes needed to transform the clinical and translational research environment in our participating institutions. The Administrative Core is responsible for the leadership and management structure for effectively managing, coordinating and supervising the Advance-CTR. The leadership structure builds upon the Culture of Collaboration demonstrated by the numerous examples of inter-institutional high impact awards that have been received and that support this IDeA-CTR. The structure ensures representation by working across a statewide consortium of universities, hospitals, government agencies, non- profits, industry partners, and the Departments of Health to impact the health of Rhode Islanders. Within Brown University, Advance-CTR collaborations extend across the Division of Biology and Medicine, the Alpert Medical School, the Program in Biology, the School of Public Health, the School of Engineering, and other Institutes and Centers. At the University of Rhode Island, we impact the Colleges of Pharmacy, Nursing, and Environment & Life Sciences. Through strategic partnerships with the Rhode Island Quality Institute and access to the All Payor Claims Database, we are able to evaluate the health care of all of Rhode Islanders through truly population based epidemiological studies, population phenotyping and clinical surveys. This IDeA-CTR proposal has the following Specific Aims: 1) Provide the organizational structure, leadership, governance, and advisory support to develop, maintain, and enhance Advance-CTR Core activities in support of clinical and translational research. 2) Enable the development, coordination, and implementation of strategic initiatives and manage the business, financial, communication, and evaluation functions necessary to ensure efficient operations and to foster growth and the long-term sustainability of Advance-CTR. 3) Serve as a source for developing written policies and procedures necessary for effective organization governance and long-term sustainability of Advance-CTR and retention of clinical research investigators.