Whole genome sequencing based tracking of pathogens in Animal Diagnostic Specimens

摘要 这项提议的目标是使动物疾病研究实验室(ADRDL)， 南达科他州将作为CVM Vet-LIRN的全基因组测序实验室 兽医诊断实验室计划。ADRDL是全国领先的 全方位服务，动物疾病研究和诊断实验室，提供最快的， 尽可能提供最准确、最可靠的动物疾病诊断服务。 ADRDL是一个非营利性实验室，提供最先进的诊断服务和 用于检测人畜共患疾病的仪器，并进行了500多次， 每年进行1000次诊断性检查。在这个项目中，ADRDL将接收来自其他国家的分离物 Vet-LIRN网络中的源实验室，这些分离物的基因组序列，执行 对数据进行生物信息学分析，并将原始数据和结果提交给Vet-LIRN 项目办公室和NCBI序列读取档案。

Abstract The goal of this proposal is to enable the Animal Disease Research Laboratory(ADRDL), South Dakota to serve as a whole genome sequencing laboratory for CVM Vet-LIRN Veterinary Diagnostic Laboratory Program. ADRDL is one of the nationally preeminent full service, animal disease research and diagnostic laboratories that provides the fastest, most accurate, and most dependable animal disease diagnostic services possible. ADRDL is a not-for-profit lab and provides state-of-the-art diagnostic services and instrumentation for the detection of zoonotic and animal diseases and conducts over 500, 000 diagnostic tests every year. In this project, ADRDL will receive isolates from other source labs in Vet-LIRN network, sequence genomes of those isolates, perform bioinformatics analysis of the data and submit the raw data and results to Vet-LIRN program office and NCBI sequence read archive.