ASBMR Three Year Pre-Meeting Symposia
ASBMR 三年会前研讨会
基本信息
- 批准号:10468525
- 负责人:
- 金额:$ 4.3万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-06-01 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAffectAmericanAreaAwardBasic ScienceBiologicalBiologyBone DiseasesCellsClinicClinicalClinical ResearchClinical TrialsDefectDevelopmentDiabetes MellitusDiseaseEndocrineEnergy MetabolismEvolutionFunctional disorderFundingGenesGeneticGoalsGrantHealthHormonesHypoxiaImaging technologyInternationalKnowledgeLaboratoriesMalignant NeoplasmsMediatingMedical SocietiesMetabolic DiseasesMetabolismMineralsMitochondriaMorbidity - disease rateMusculoskeletalMusculoskeletal DiseasesOrganOsteocytesOsteoporosisPathogenesisPatient CarePatientsProfessional OrganizationsRare DiseasesRecording of previous eventsResearchResearch PersonnelRoleScienceScientific SocietiesScientistSeriesSignal TransductionSkeletal DevelopmentSkeletonSocietiesState-of-the-Art ReviewsSyndromeTherapeuticTherapeutic UsesTranslatingTranslational ResearchUnited States National Institutes of HealthUpdateWomanbasebonebone healthdirect applicationdisabilitydrug discoverydrug repurposingeffective therapygenetic technologyimprovedinnovationinterestmeetingsmenmortalitynovel strategiesnovel therapeuticsposterspre-clinicalpreclinical developmentpreventprogramsresponseskeletalskeletal disordersuccesssymposiumtherapeutic target
项目摘要
The American Society for Bone and Mineral Research (ASBMR), the largest professional, scientific and medical
society established to bring together clinical and laboratory-based scientists who are involved in the study of
bone, mineral and musculoskeletal science, has had a successful history of conducting annual topical meetings
funded by single year NIH R13 grants since 2002. More recently, ASBMR received two, three-year R13 grants
to cover pre-meeting symposia programs for 2016-2018 and 2019-2021. The current application seeks funding
for a three-year R13 grant to advance the field of musculoskeletal diseases by focusing on three specific areas
of scientific research in 2022, 2023 and 2024: 1) “Rare Diseases: From Molecules and Mechanisms to
Therapeutics”; 2) “Osteocytes in Bone Health and Disease and as Therapeutic Target Cells”; 3) “Energy
Metabolism in Skeletal Development and Disease”. These three symposia cover highly relevant areas of
musculoskeletal research that has recently undergone rapid evolution in scientific knowledge and collectively
contribute to major clinical morbidity disability and mortality. The overall objective of this R13 is to stimulate
further advances that will result in improved patient care for musculoskeletal diseases by bringing together the
best researchers for each of the three symposia. The symposia will review the state of the art in each topic area,
exchanging ideas with attendees, and stimulating the interaction between young and established researchers.
Symposia attendees will be encouraged to attend the subsequent ASBMR Annual Meetings for additional
opportunities to interact with musculoskeletal researchers. Programs for all three symposia were developed by
an organizing committee, and all speakers for the first two symposia have confirmed their participation.
Presenters include established and young investigators, women and men, and, since about half of ASBMR
membership is from outside the US, a number of key international speakers have also been invited. Poster
sessions, young investigator award presentations, and at the end of each meeting a “dine-around” evening are
planned to promote direct interaction between young investigators and more senior speakers. In 2022, the
symposium will gather international experts in rare bone diseases to discuss the latest advances on underlying
mechanisms and therapies, provide guidance to clinicians on how to recognize them, and lessons learnt from
rare diseases that have direct application to more common bone diseases such as osteoporosis. In 2023, the
symposium will review the advances in basic, translational and clinical research on the role of osteocytes in the
biology and pathophysiology of bone, and how to target osteocytes with therapeutic goals. The osteocyte role in
mechanobiology, hormone actions, cancer in bone and osteocyte endocrine actions will be discussed. The 2024
symposium will discuss the recent advances on the role of energy metabolism in skeletal development and
disease; including the role of hypoxia and mitochondria-mediated mechanisms, and its involvement in the
response of bone to anabolic therapies and metabolic diseases such as diabetes.
美国骨与矿物研究学会(ASBMR),最大的专业、科学和医学
为汇聚临床和实验室科学家而成立的学会,这些科学家参与了对癌症的研究
骨、矿物和肌肉骨骼科学,有举办年度专题会议的成功历史。
自2002年以来,由美国国立卫生研究院R13年度拨款资助。最近,ASBMR获得了两笔为期三年的R13赠款
涵盖2016-2018年和2019-2021年的会前座谈会计划。目前的申请正在寻求资金
提供为期三年的R13赠款,通过重点关注三个具体领域来促进肌肉骨骼疾病领域的发展
2022年、2023年和2024年科学研究奖:1)《罕见病:从分子和机制到
治疗学“;2)”骨健康和疾病中的骨细胞及其作为治疗靶细胞“;3)”能量“
骨骼发育和疾病中的代谢“。这三个研讨会涵盖了以下高度相关的领域
最近在科学知识和集体方面经历了快速演变的肌肉骨骼研究
导致严重的临床发病率、残疾和死亡率。此R13的总体目标是刺激
进一步的进展将导致改善肌肉骨骼疾病的患者护理
三次研讨会中每一次都是最佳研究人员。座谈会将回顾每个主题领域的最新进展,
与与会者交流思想,促进年轻研究人员和知名研究人员之间的互动。
研讨会与会者将被鼓励参加随后的ASBMR年会,以获得更多
与肌肉骨骼研究人员互动的机会。所有三个研讨会的节目都是由
组委会和前两次研讨会的所有发言者都已确认参加。
演讲者包括成熟的和年轻的调查人员,女性和男性,由于ASBMR约有一半
成员来自美国以外的国家,一些重要的国际演讲者也被邀请。海报
会议、青年调查员颁奖典礼,以及在每次会议结束时的“共进晚餐”之夜是
计划促进青年调查人员与更资深的发言者之间的直接互动。2022年,
研讨会将汇集国际罕见骨病专家,讨论有关骨科疾病的最新进展。
机制和疗法,为临床医生提供如何识别它们的指导,以及从中吸取的教训
直接应用于骨质疏松症等更常见的骨骼疾病的罕见疾病。2023年,
研讨会将综述骨细胞在骨移植中的作用的基础、翻译和临床研究的进展。
骨的生物学和病理生理学,以及如何以骨细胞为治疗目标。骨细胞在成骨细胞中的作用
将讨论机制生物学、激素作用、骨癌和骨细胞内分泌作用。2024年
研讨会将讨论能量代谢在骨骼发育中的作用和最新进展
疾病,包括缺氧的作用和线粒体介导的机制,以及它在
骨骼对合成代谢疗法和代谢性疾病如糖尿病的反应。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Teresita M. Bellido其他文献
The development of a collagen-nanoscale hydroxyapatite three-dimensional (3D) emin vitro/em culture system for reproducing osteocyte differentiation and tissue mineralization
用于复制骨细胞分化和组织矿化的胶原蛋白-纳米羟基磷灰石三维(3D)体外培养系统的开发
- DOI:
10.1016/j.biomaterials.2025.123451 - 发表时间:
2026-01-01 - 期刊:
- 影响因子:12.900
- 作者:
Xiaoyu Xu;Brian T. Golz;Brennan T. Flannery;Maxime A. Gallant;Whitney A. Bullock;Teresita M. Bellido;Eric A. Nauman;Sherry L. Voytik-Harbin;Dianne Little;Russell P. Main - 通讯作者:
Russell P. Main
Allogeneic Mesenchymal Stromal Cells Increase In Vivo Muscle Function and Promote Muscle Fiber Regeneration in a Diabetic Mouse Model of Critical Limb-Threatening Ischemia
- DOI:
10.1016/j.jvs.2020.06.057 - 发表时间:
2020-09-01 - 期刊:
- 影响因子:
- 作者:
Justin R. King;Katherin E. Leckie;Amy Y. Sato;Teresita M. Bellido;Marlee Yancey;Leni Moldovan;Michael P. Murphy;Steven J. Miller - 通讯作者:
Steven J. Miller
Teresita M. Bellido的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Teresita M. Bellido', 18)}}的其他基金
Glucocorticoid-induced Atrophy in Bone and Muscle
糖皮质激素引起的骨和肌肉萎缩
- 批准号:
10301368 - 财政年份:2020
- 资助金额:
$ 4.3万 - 项目类别:
Glucocorticoid-induced Atrophy in Bone and Muscle
糖皮质激素引起的骨和肌肉萎缩
- 批准号:
10225876 - 财政年份:2020
- 资助金额:
$ 4.3万 - 项目类别:
Glucocorticoid-induced Atrophy in Bone and Muscle
糖皮质激素引起的骨和肌肉萎缩
- 批准号:
10463792 - 财政年份:2020
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
9911968 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
10618285 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
10265416 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
10328422 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
9764747 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
BLR&D Research Career Scientist Award Application for Teresita Bellido, PhD
BLR
- 批准号:
10454217 - 财政年份:2019
- 资助金额:
$ 4.3万 - 项目类别:
相似海外基金
How Does Particle Material Properties Insoluble and Partially Soluble Affect Sensory Perception Of Fat based Products
不溶性和部分可溶的颗粒材料特性如何影响脂肪基产品的感官知觉
- 批准号:
BB/Z514391/1 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Training Grant
BRC-BIO: Establishing Astrangia poculata as a study system to understand how multi-partner symbiotic interactions affect pathogen response in cnidarians
BRC-BIO:建立 Astrangia poculata 作为研究系统,以了解多伙伴共生相互作用如何影响刺胞动物的病原体反应
- 批准号:
2312555 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Standard Grant
RII Track-4:NSF: From the Ground Up to the Air Above Coastal Dunes: How Groundwater and Evaporation Affect the Mechanism of Wind Erosion
RII Track-4:NSF:从地面到沿海沙丘上方的空气:地下水和蒸发如何影响风蚀机制
- 批准号:
2327346 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Standard Grant
Graduating in Austerity: Do Welfare Cuts Affect the Career Path of University Students?
紧缩毕业:福利削减会影响大学生的职业道路吗?
- 批准号:
ES/Z502595/1 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Fellowship
Insecure lives and the policy disconnect: How multiple insecurities affect Levelling Up and what joined-up policy can do to help
不安全的生活和政策脱节:多种不安全因素如何影响升级以及联合政策可以提供哪些帮助
- 批准号:
ES/Z000149/1 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Research Grant
感性個人差指標 Affect-X の構築とビスポークAIサービスの基盤確立
建立个人敏感度指数 Affect-X 并为定制人工智能服务奠定基础
- 批准号:
23K24936 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
How does metal binding affect the function of proteins targeted by a devastating pathogen of cereal crops?
金属结合如何影响谷类作物毁灭性病原体靶向的蛋白质的功能?
- 批准号:
2901648 - 财政年份:2024
- 资助金额:
$ 4.3万 - 项目类别:
Studentship
Investigating how double-negative T cells affect anti-leukemic and GvHD-inducing activities of conventional T cells
研究双阴性 T 细胞如何影响传统 T 细胞的抗白血病和 GvHD 诱导活性
- 批准号:
488039 - 财政年份:2023
- 资助金额:
$ 4.3万 - 项目类别:
Operating Grants
New Tendencies of French Film Theory: Representation, Body, Affect
法国电影理论新动向:再现、身体、情感
- 批准号:
23K00129 - 财政年份:2023
- 资助金额:
$ 4.3万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
The Protruding Void: Mystical Affect in Samuel Beckett's Prose
突出的虚空:塞缪尔·贝克特散文中的神秘影响
- 批准号:
2883985 - 财政年份:2023
- 资助金额:
$ 4.3万 - 项目类别:
Studentship