International Bordetella Symposia

项目概要/摘要： 百日咳又称百日咳，是一种由细菌病原体博德特氏菌引起的呼吸道疾病 百日咳。百日咳是世界上疫苗可预防死亡的主要原因之一， 疫苗可预防的细菌性疾病，发病率正在上升。尽管疫苗覆盖率很高， 咳嗽（百日咳）在美国和全世界重新成为主要的公共卫生问题。近日有 据估计，大约有2400万例百日咳病例和160，700例5岁以下儿童死亡， 世界每年。除了在2015年被添加到NIH新兴传染性病原体名单外，CDC 最近在2019年抗生素耐药性威胁报告中将百日咳杆菌列入其新的观察名单 因为这种高度传染性细菌的未知未来负担。自20世纪60年代以来， 研究界组织了一次国际博德特氏菌研讨会，第12次研讨会在 布鲁塞尔大学由Camille Locht博士于2019年4月。为了增加新数据的传播， 为了交流思想，Ciaran Skerry博士在马里兰州大学主持了第一届博德特氏菌研究日 2018年4月博德特氏菌研究日原本是为博德特氏菌研究人员举办的一次美国会议 在国际博德特氏菌研讨会的淡季见面。由于COVID-19大流行， 2020年博德特氏菌研究日和2021年国际博德特氏菌研讨会被推迟。到 为了继续传播重要的研究成果，国际博德特氏菌学会主办了一个基于动物模型的 会议于2020年8月举行，吸引了学术界，CDC，FDA，NIH和许多 制药公司。这一在线活动的重大成功导致博德特氏菌学会创建了一个 每月举行一次实验室会议系列，世界各地的不同团体可以在其中展示他们的最新研究。在 为了进一步支持下一代科学家的发展，R13应用程序要求 资助初级科学家（博士前和博士后）出席和出席会议的相关差旅费 在不列颠哥伦比亚省大学举办的第13届国际博德特氏菌研讨会上的创新研究 在加拿大温哥华举行（2022年6月）。

Project Summary/Abstract: Whooping cough, also known as Pertussis, is a respiratory disease caused by the bacterial pathogen Bordetella pertussis. Pertussis is one of the world’s leading causes of vaccine-preventable deaths and is currently the only vaccine-preventable bacterial disease that is increasing in incidence. Despite high vaccine coverage, whooping cough (pertussis) has re-emerged as a major public health concern in the US and the world. Recently, it was estimated that there were 24 million pertussis cases and 160,700 deaths in children younger than 5 years around the world per year. In addition to being added to the NIH emerging infectious pathogens list in 2015, the CDC recently listed Bordetella pertussis on its new Watch List in the 2019 Antibiotic Resistance Threats Report because of the unknown future burden of this highly contagious bacterium. Since the 1960’s, the Bordetella research community has organized an International Bordetella Symposium, the 12th symposium was hosted at Brussels University by Dr. Camille Locht, in April of 2019. In an effort to increase dissemination of new data and exchange of ideas, Dr. Ciaran Skerry hosted the 1st ever Bordetella Research Day at the University of Maryland in April, 2018. The Bordetella Research Day was meant to be a U.S-based conference for Bordetella researchers to meet during the off years of the International Bordetella Symposiums. Due to the COVID-19 pandemic, both the 2020 Bordetella Research Day, and the 2021 International Bordetella Symposium were postponed. To continue dissemination of important research, the International Bordetella Society hosted a zoom-based conference in August 2020 which garnered attendance from academia, the CDC, FDA, NIH, and many pharmaceutical companies. The major success of this online event resulted in the Bordetella Society creating a monthly Lab Meeting Series, where different groups around the world can showcase their latest research. In order to further support the development of the next generation of scientists, this R13 application is requesting funds to support travel associated costs for junior scientists (pre- and post-doctoral) to attend and present innovative research at the 13th International Bordetella Symposium hosted at the University of British Columbia in Vancouver, Canada (June 2022).