Support for Graduate, PDF and New Faculty Presenters at the 2022 American Society of Pharmacognosy Meeting

项目摘要/摘要 天然产品通过提供治疗作用，为人类提供了支持健康的关键起始材料 用于药物化学家的试剂和结构模板。天然产品领域正在迅速演变，以填补 预计供应缺口，原因是远离以石油为基础的能源、精细化学品和 制药公司。尽管每桶石油中只有1%左右用于制药生产 产品据估计，石油为医药等消费品提供99%的原料 产品。因此，本次会议的三个主要目标之一包括替换基于石油的削减战略武器 天然产品的治疗材料。本次会议的第二个主要目标是评估泛美经济学。 发现和开发控制癌症和癌症的天然产品原型的方法 新出现的传染病，包括SARS-CoV2。在药物发现中应用低温电子显微镜的新兴方法 发展将是本次会议的主要议题。需要更好地控制新出现的传染病 不需要解释；然而，天然产品作为关键的起始材料和新原型的作用将 将作为2022年美国生药学学会会议的一部分发表讲话。最后，第三个关键目标是 该计划是为了评估天然产品和天然产品调查人员在控制 环境中的二氧化碳水平。这可以采取农业光合作用的形式或直接 将二氧化碳转化为制药和其他消费品的原料。我们完全 预计NPs将在未来很好地满足人类健康在新原型方面的需求。这 会议将展示这些新兴需求的许多方面，以及正在发展的尖端方法 赛场加速前进。我们挑选了该领域的领导人担任会议主席和发言人。 这与NCCIH的使命非常一致，包括大量具有以下专业知识的演讲者 用于评估和标准化用作补充药物的材料的分析技术。这个项目 寻求资金支持将于7月23-28日举行的美国生药学学会(ASP)会议 南卡罗来纳州查尔斯顿。ASP是美国最大的专注于天然产品的协会。ASP也是如此 因为这次会议的重点是来自自然的分子及其应用来改善人类健康。支持 将帮助抵消注册费，并帮助来自美国和 美国领土，重点是东南部的地区性HBCU(历史上的黑人学院和大学) 我们。因此，我们的最终目标是通过招募和支持与会者来培养下一代科学家 来自Puis，重点放在美国东南部。

PROJECT SUMMARY/ABSTRACT Natural products have provided humankind the key starting materials to support health by providing therapeutic agents and structural templates for medicinal chemists. The field of natural products is rapidly evolving to fill anticipated supply gaps due to the movement away from petroleum based energy, fine chemicals and pharmaceuticals. Although only about 1% of every barrel of oil is used in the manufacture of pharmaceutical products it is estimated petroleum supplies 99% of the starting materials for pharmaceutical and other consumer products. Thus one of three key Aims of this meeting includes the replacement of petroleum based starting materials for therapeutics with natural products. A second key aim for this meeting is an assessment of panomics approaches to the discovery and development of natural product prototypes for the control of cancer and emerging infectious diseases, including SARS-CoV2. Emerging methods involving CryoEM in drug discovery and development will be featured at this meeting. The need for better controls for emerging infectious diseases needs no explanation; however; the role of natural products as critical starting materials and new prototypes will be addressed as part of the 2022 American Society of Pharmacognosy Conference. Finally, a third key aim of the program is to assess the role that natural products and natural products investigators can play in controlling carbon dioxide levels in the environment. This can take the form of photosynthesis of agriculture or direct conversion of CO2 into the starting materials for pharmaceuticals and other consumer products. We fully anticipate that NPs will serve the needs of human health in regard to new prototypes well into the future. This conference will showcase many aspects of these emerging needs with cutting-edge approaches that are moving the field forward at an accelerated pace. We have selected leaders in the field as conference chairs and speakers that align well with the mission of the NCCIH including a significant number of speakers with expertise in analytical techniques for evaluating and standardizing materials used as complementary medicines. This project seeks funding to support the American Society of Pharmacognosy (ASP) meeting that will be held July 23-28th in Charleston, SC. The ASP is the largest society in the USA that focuses on natural products. The ASP as well as this conference focuses on molecules from nature and their application to improve human health. Support from the NIH will help offset registration fees and assist with travel for students and new faculty from the US and US Territories with a focus on regional HBCUs (historically black colleges and universities) of the South Eastern US. Thus our final aim is to train the next generation of scientists through the recruitment and support attendees from the PUIs with a focus on the Southeastern US.