Support for Graduate, PDF and New Faculty Presenters at the 2022 American Society of Pharmacognosy Meeting

为 2022 年美国生药学会会议上的研究生、PDF 和新教师演讲者提供支持

• 批准号: 10469168
• 负责人: Mark T Hamann
• 金额: $ 3万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10469168
• 关键词: 2019-nCoV; Address; Agriculture; American; Area; Back; Beauty; Biology; Caliber; Cancer Control; Carbon Dioxide; Chemicals; Clinical Research; Collaborations; Communities; Complementary Medicine; Core Facility; Country; Cryoelectron Microscopy; Development; Dictionary; Disease; Dyes; Education; Educational workshop; Emerging Communicable Diseases; Environment; Environmental Science; Equilibrium; Event; Faculty; Fees; Fostering; Funding; Future; Goals; Health; Historically Black Colleges and Universities; Human; Institution; Island; Knowledge; Laboratories; Marine Biology; Medical; Medicine; Methods; Mission; Movement; Municipalities; National Center for Complementary and Integrative Health; National Oceanic and Atmospheric Administration; Natural History; Natural Products; Nature; Oils; Petroleum; Pharmaceutical Preparations; Pharmacognosy; Pharmacologic Substance; Photosynthesis; Plants; Play; Population Heterogeneity; Postdoctoral Fellow; Production; Recording of previous events; Research; Research Personnel; Role; Science; Scientist; Social Interaction; Societies; Source; South Carolina; Southeastern United States; Standardization; Students; Techniques; Therapeutic; Therapeutic Agents; Training; Training and Education; Travel; Underrepresented Populations; United States National Institutes of Health; Universities; Women' s Group; Work; base; career; career development; college; consumer product; drug development; drug discovery; global health; graduate student; improved; indigo dye; innovation; instrument; interest; medical schools; meetings; member; men' s group; neglect; nervous system disorder; next generation; outreach; programs; prototype; recruit; small molecule; social; student mentoring; symposium; synthetic biology; translational study

PROJECT SUMMARY/ABSTRACT Natural products have provided humankind the key starting materials to support health by providing therapeutic agents and structural templates for medicinal chemists. The field of natural products is rapidly evolving to fill anticipated supply gaps due to the movement away from petroleum based energy, fine chemicals and pharmaceuticals. Although only about 1% of every barrel of oil is used in the manufacture of pharmaceutical products it is estimated petroleum supplies 99% of the starting materials for pharmaceutical and other consumer products. Thus one of three key Aims of this meeting includes the replacement of petroleum based starting materials for therapeutics with natural products. A second key aim for this meeting is an assessment of panomics approaches to the discovery and development of natural product prototypes for the control of cancer and emerging infectious diseases, including SARS-CoV2. Emerging methods involving CryoEM in drug discovery and development will be featured at this meeting. The need for better controls for emerging infectious diseases needs no explanation; however; the role of natural products as critical starting materials and new prototypes will be addressed as part of the 2022 American Society of Pharmacognosy Conference. Finally, a third key aim of the program is to assess the role that natural products and natural products investigators can play in controlling carbon dioxide levels in the environment. This can take the form of photosynthesis of agriculture or direct conversion of CO2 into the starting materials for pharmaceuticals and other consumer products. We fully anticipate that NPs will serve the needs of human health in regard to new prototypes well into the future. This conference will showcase many aspects of these emerging needs with cutting-edge approaches that are moving the field forward at an accelerated pace. We have selected leaders in the field as conference chairs and speakers that align well with the mission of the NCCIH including a significant number of speakers with expertise in analytical techniques for evaluating and standardizing materials used as complementary medicines. This project seeks funding to support the American Society of Pharmacognosy (ASP) meeting that will be held July 23-28th in Charleston, SC. The ASP is the largest society in the USA that focuses on natural products. The ASP as well as this conference focuses on molecules from nature and their application to improve human health. Support from the NIH will help offset registration fees and assist with travel for students and new faculty from the US and US Territories with a focus on regional HBCUs (historically black colleges and universities) of the South Eastern US. Thus our final aim is to train the next generation of scientists through the recruitment and support attendees from the PUIs with a focus on the Southeastern US.

项目总结/摘要 天然产品为人类提供了关键的起始材料，通过提供治疗， 药剂和结构模板。天然产品领域正在迅速发展， 由于石油能源、精细化学品和 大药厂尽管每桶石油中只有约1%用于制药 据估计，石油为制药和其他消费品提供了99%的起始原料。 产品.因此，本次会议的三个主要目标之一包括取代石油为基础的启动 天然产物的治疗材料。这次会议的第二个关键目标是对泛经济学进行评估 发现和开发用于控制癌症的天然产品原型的方法， 新出现的传染病，包括SARS-CoV 2。CryoEM在药物发现中的新兴方法 和发展将在这次会议上。需要更好地控制新出现的传染病 不需要解释;然而;天然产物作为关键起始材料和新原型的作用将 作为2022年美国生药学学会会议的一部分。最后，第三个关键目标是 该计划旨在评估天然产品和天然产品调查人员在控制 环境中的二氧化碳含量。这可以采取农业光合作用的形式， 将二氧化碳转化为药品和其他消费品的原材料。我们完全 预计纳米粒子将在未来很长一段时间内为人类健康的新原型需求服务。这 会议将展示这些新兴需求的许多方面，并采用先进的方法， 场地以更快的速度向前推进。我们选择了该领域的领导者作为会议主席和发言人 这符合NCCIH的使命，包括大量具有以下专业知识的演讲者 用于评估和标准化用作补充药物的材料的分析技术。这个项目 寻求资金支持将于7月23日至28日举行的美国生药学学会（ASP）会议 ASP是美国最大的专注于天然产品的协会。ASP也 因为这次会议的重点是来自自然界的分子及其在改善人类健康方面的应用。支持 美国国立卫生研究院的资金将帮助抵消注册费，并帮助来自美国的学生和新教师旅行， 美国领土，重点是东南部的区域HBCU（历史上的黑人学院和大学） 我们因此，我们的最终目标是通过招募和支持与会者来培养下一代科学家 重点关注美国东南部地区。