2/2 Partnership for Native American Cancer Prevention

项目总结/摘要：总体 美洲原住民癌症预防伙伴关系（NACP）在解决癌症问题方面具有独特的地位。 美国原住民社区的健康不平等。癌症是原住民的第二大死因 45岁以上的美国人。尽管癌症筛查技术和主要的 在过去的几十年里，癌症治疗的发展，部落社区并没有从中平等受益。 预付款。此外，美国国立卫生研究院认识到，美洲原住民的代表性最低， 生物医学研究工作人员中代表性不足的群体，这有助于整体癌症健康 对这个群体的不公平。NACP始于2002年，是北方亚利桑那大学 (NAU)，作为服务于服务不足的健康差距人口和代表性不足的学生的机构， 亚利桑那大学癌症中心（UACC），作为综合癌症中心。总体 NACP的目标是增加NAU的癌症研究和UACC的癌症健康差异能力， 尊重现有的并建立新的美洲原住民社区伙伴关系。为了实现这些目标， 提出了以下目标：目标1。开展试点研究项目和全面研究项目， 解决美洲原住民癌症差异，反映社区关切;目标2.招聘和支持 美国原住民教师专注于癌症研究;目标3。创建名为“Guiding”的新共享资源 U 54研究者发展到可持续发展（GUIDES）”，目标是促进NACP的过渡- 附属，早期研究者/初级研究者研究独立性;目标4。扩大和 实施癌症差异研究教育，重点是NAU/UA的美洲原住民学生 本科和研究生课程;目标5。将社区参与原则纳入所有NACP 活动，促进传播伙伴关系的研究成果和国家外联网络的 对美国原住民社区的倡议。为达致这些目标，政府现正推行两项全面计划及一项先导计划， 两人都是美国人，两人都是美国人。一个完整的项目和试点项目联合收割机基本 科学和社区参与的研究，以解决胃癌和宫颈癌;死亡率为这些 癌症在美洲原住民中更高。我们建议行政、规划和评价， 研究教育、外展和GUIDES核心，以支持研究项目和整合活动 在伙伴关系中。NAU和UACC承诺提供机构资金支持新项目和本地项目 美国调查员。该提案中的新优先事项是社区参与的研究，这将影响癌症 筛选率，招募和指导美洲原住民早期研究人员，资助写作活动 支持以美洲原住民为重点的癌症差异研究和倡议，以及联合研究教育 课程，以发展一个更强大的美国土著生物医学劳动力。截至拟议供资结束时 在此期间，NACP将使亚利桑那州的美洲原住民更接近癌症健康平等。

PROJECT SUMMARY/ABSTRCT: OVERALL The Partnership for Native American Cancer Prevention (NACP) is uniquely positioned to address cancer health inequities in Native American communities. Cancer is the second leading cause of death for Native Americans over the age of 45 years. Despite improvements in cancer screening techniques and major developments in cancer treatment in past decades, tribal communities have not benefited equally from these advances. Further, the NIH recognizes that Native Americans have the lowest representation of all underrepresented groups in the biomedical research workforce, which contributes to the overall cancer health inequities for this population. NACP began in 2002 as a partnership between Northern Arizona University (NAU), as the institution serving underserved health disparity populations and underrepresented students, and the University of Arizona Cancer Center (UACC), as the Comprehensive Cancer Center. The overarching goals of NACP are to increase NAU's cancer research and UACC's cancer health disparities capacities by honoring existing and establishing new Native American community partnerships. To meet these goals, the following aims are proposed: Aim 1. Conduct Pilot Research Projects and Full Research Projects, which address Native American cancer disparities and reflect community concerns; Aim 2. Recruit and support Native American faculty focused on cancer research; Aim 3. Create a new shared resource called “Guiding U54 Investigator Development to Sustainability (GUIDeS)“ with the goal to facilitate the transition of NACP- affiliated, Early Stage Investigators/Junior Investigators to research independence; Aim 4. Expand and implement cancer disparities research education with a focus on Native American students across NAU/UA undergraduate and graduate programs; Aim 5. Integrate community engagement principles into all NACP activities, facilitating dissemination of the Partnership's research findings and the National Outreach Network's initiatives to Native American communities. To achieve these Aims, two Full and one Pilot project are proposed; two have Native American co-leaders. One of the Full projects and the Pilot project combine basic science and community engaged research to address gastric and cervical cancer; death rates for these cancers are higher in Native American populations. We propose Administrative, Planning and Evaluation, Research Education, Outreach and GUIDeS Cores to support the research projects and integrate activities across the Partnership. NAU and UACC commit institutional funds to support new projects and Native American investigators. New priorities in this proposal are community engaged research that will impact cancer screening rates, recruitment and mentoring of Native American early stage investigators, grant writing activities to sustain Native American-focused cancer disparities research and initiatives, and joint research education curricula to develop a stronger Native American biomedical workforce. By the end of the proposed funding period, NACP will move Native Americans in Arizona closer to cancer health equity.