Promoting Cervical Cancer Screening among African American and Sub-Saharan African Immigrant women

促进非裔美国人和撒哈拉以南非洲移民妇女的宫颈癌筛查

• 批准号: 10475204
• 负责人: Adebola O Adegboyega
• 金额: $ 15.34万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10475204
• 关键词: Address; Africa South of the Sahara; African; African American; African American population; Awareness; Behavior Therapy; Belief; Black Populations; Cancer Control; Cancer Etiology; Central Asia; Cervical; Cervical Cancer Screening; Cessation of life; Clinic Visits; Clinical Trials Design; Collection; Consent; Cross-Sectional Studies; Data; Death Rate; Developing Countries; Development; Development Plans; Diagnosis; Education; Emotional; Environment; Evidence based intervention; Extramural Activities; Frequencies; Fright; Funding; Future; Geographic Locations; Goals; Health; Health Promotion; Health behavior; Health education; Healthcare Systems; Human Papillomavirus; Human papilloma virus infection; Immigrant; Incidence; Individual; Intervention; Intervention Studies; Irrigation; K-Series Research Career Programs; Kentucky; Knowledge; Lesion; Literature; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentored Research Scientist Development Award; Mentors; Methods; Minority; Minority Women; Modality; Modeling; Not Hispanic or Latino; Outcome; Outcome Measure; Pattern; Physicians; Population; Population Heterogeneity; Population Study; Preventative vaccination; Prevention; Privatization; Quality of Care; Quasi-experiment; Race; Randomized Clinical Trials; Research; Research Personnel; Research Training; Resources; Role; Sampling; Screening for cancer; Screening procedure; Self Efficacy; Sensitivity and Specificity; South America; Structure; Subgroup; Swab; Testing; Time; Training; Treatment Efficacy; Underserved Population; United States; Universities; Visit; Vulnerable Populations; Woman; aged; anticancer research; behavior change; behavior influence; black men; black subgroup; black women; cancer health disparity; cancer prevention; career; career development; cervical cancer prevention; cost; evidence base; experience; health belief; health care availability; health knowledge; high risk; high risk population; innovation; intervention effect; mortality; peer; pilot test; prevent; programs; racial and ethnic disparities; recruit; research study; satisfaction; screening; screening participation; skills; social; social cognitive theory; underserved minority; willingness

‐ PROJECT SUMMARY/ABSTRACT The highest incidence rates of cervical cancer (CC) are in sub-Saharan Africa, South Central Asia and South America. In the United States (U.S.), CC ranks 14th in frequency. However, in certain populations and geographic areas of the U.S., CC incidence and death rates are significantly higher, due in part to racial and ethnic disparities in access, utilization, and quality of care, all of which contribute to worse health outcomes. Black women experience a disparate burden of CC incidence and mortality, having a higher risk of being diagnosed with and dying from CC than non-Hispanic White women. Appropriate and timely CC screening is a key factor in prevention. Leveraging the positive benefits of CC screening may reduce the CC disparate burden among Blacks. Research studies typically treat Blacks as a homogeneous group, despite differences within this population. To begin to address a gap in the literature within the scope of a career development award, this study focuses specifically on two subgroups of Black women - African Americans (AA) and Sub-Saharan African immigrants (SAI) given that there is paucity of research with SAI despite known cancer related disparities among SAI women. To promote screening for these underserved minority women, we will conduct research to better understand factors that influence engagement in cancer screening practices and willingness to conduct HPV self-sampling in which women self-collect samples for HPV testing using a swab, brush or lavage. Guided by the findings, we will develop and pilot test an innovative tailored intervention incorporating HPV self-sampling with peer-delivered education. The specific aims are to (1) examine general awareness and cultural factors related to cancer control and prevention among AA and SAIs; (2) examine the socioecological barriers and facilitators to CC screening with HPV self-sampling to tailor an evidenced based cervical health promotion program in these underserved subgroups; and (3) assess feasibility, acceptability, and preliminary efficacy of the intervention. The intervention, entitled Health is Wealth: A Cervical Health Program, will be pilot tested with 30 AA and 30 SAI women aged 30 to 65 years using a quasi-experimental design. These aims will also support the candidate’s career goal of developing an independent and extramurally funded program of research to promote cancer control and prevention for minority women. To further support this goal, a mentored career development plan consisting of training in mixed methods, adaptation and development of behavioral interventions, randomized clinical trial design, and research team management, is proposed. The rich research environment at the University of Kentucky and the expertise of the mentoring team will provide the supplemental resources and support needed for the candidate to successfully complete the proposed research and training plans. As such, this K01 award will provide the training, mentoring, and research experiences needed for the candidate to successfully compete for a R01-level CC screening intervention study and expedite her career development.

- 项目摘要/摘要 宫颈癌发病率最高的地区是撒哈拉以南非洲、中亚南部和南部。 美国。在美国，CC的使用频率排在第14位。然而，在某些人群和地理位置 在美国的一些地区，CC的发病率和死亡率明显较高，部分原因是种族和民族差异 在可获得性、利用率和护理质量方面，所有这些都会导致更糟糕的健康结果。黑人女性 经历CC发病率和死亡率的不同负担，具有更高的被诊断为 死于CC的女性比非西班牙裔白人女性多。适当和及时的CC筛查是关键因素 预防。利用CC筛查的积极好处可能会减少以下人群的CC不同负担 黑人。研究通常将黑人视为同质群体，尽管其中存在差异 人口。为了开始解决职业发展奖范围内文献中的一个空白，这 这项研究特别关注黑人女性的两个亚群--非洲裔美国人(AA)和撒哈拉以南非洲人 移民(SAI)，尽管已知与癌症相关的差异，但对SAI的研究很少 赛族妇女。为了促进对这些服务不足的少数族裔妇女的筛查，我们将进行研究，以更好地 了解影响参与癌症筛查实践和进行HPV的意愿的因素 自我采样，即女性使用棉签、刷子或洗涤剂自行采集样本进行HPV检测。在指导下 发现，我们将开发和试点测试一种创新的量身定制的干预措施，将HPV自我采样与 同伴传授的教育。具体目的是(1)考察一般意识和相关的文化因素 在AA和SAI中控制和预防癌症；(2)检查社会生态障碍和促进者 用HPV自我采样进行宫颈宫颈筛查，以定制以证据为基础的宫颈健康促进计划 (3)评估干预的可行性、可接受性和初步效果。这个 名为健康就是财富：宫颈健康计划的干预措施将在30名AA和30名SAI患者中进行试点测试 年龄在30岁到65岁之间的女性使用准实验设计。这些目标也将支持候选人的 开发一个独立的、由外部资助的促进癌症的研究计划的职业目标 对少数民族妇女的控制和预防。为了进一步支持这一目标，一项有指导的职业发展计划 包括混合方法的培训，适应和发展行为干预，随机 提出了临床试验设计和研究团队管理的建议。大学丰富的研究环境 肯塔基大学和指导团队的专业知识将提供补充资源和 候选人成功完成拟议的研究和培训计划所需的支持。因此， 该K01奖项将为应聘者提供所需的培训、指导和研究经验 成功竞争R01级CC筛查干预研究，并加快她的职业发展。