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中文摘要
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项目摘要-职业提升计划 职业提升计划(CEP)的目标是招聘、培训和留住多样化的优秀人才 致力于转化性皮肤癌研究的职业早期调查人员。CEP将由 由两名在基础(维拉纽瓦博士)和临床(维拉纽瓦博士)方面具有互补专业知识的知名研究人员组成。 Schuchter)黑色素瘤研究。两位联席主任都致力于培训和指导翻译 调查人员,并有招募和支持妇女和少数群体的既定记录。CEP将 主要协助初级教员的职业发展,但更有经验的调查人员感兴趣 也可以考虑将他们的研究重点重新放在黑色素瘤/皮肤癌上。女性和 将大力鼓励代表人数不足的少数群体参加。同样,旨在解决以下问题的项目 将鼓励健康差距和/或皮肤癌亚型在代表性不足的少数族裔中更为常见 并给予特别考虑。一支由临床医生、教育工作者和研究人员组成的团队,他们在 翻译研究将确保这一计划的具体目标的实施。在世界银行的支持下 宾夕法尼亚大学、艾布拉姆森癌症中心和维斯塔尔研究所,CEP将提供初级 教职员工需要的资源和指导,以建立创新的和全额资助的独立皮肤癌 研究项目,并成为未来的学术领袖。CEP将为获奖者提供两年的 为皮肤癌转化研究项目提供资金支持,并有可能推广到全孢子项目 或独立的赠款支持。获奖者需积极参与孢子功能,利用孢子 提供核心资源,并提供正式的书面进度报告和口头陈述。我们已经确立了 对研究导师的高标准和期望,以及正式的长期获奖者计划 师徒关系。该计划通过出版出版物、资金以及最终的职业生涯来衡量成功与否 进步和国家认可。我们拥有优秀的候选人人才库和一支有效的 培训和指导计划,将导致一组特殊的皮肤癌研究人员。我们的孢子 CEP在招募和培训转化性皮肤癌研究领域的研究人员方面有着出色的记录。 我们过去的CEP获奖者在上一个周期发表了74篇论文,并非常成功地获得了 来自NCI和/或其他资助机构的同行评审资金。此外,所有过去的获奖者都已从 年轻的研究人员进入领先的学术职位,并留在皮肤癌领域。
英文摘要
Project Summary – Career Enhancement Program The goal of the Career Enhancement Program (CEP) is to recruit, train and retain a diverse pool of outstanding early-career investigators who are committed to pursuing translational skin cancer research. The CEP will be led by two established investigators with complementary expertise in basic (Dr. Villanueva) and clinical (Dr. Schuchter) melanoma research. Both co-Directors are committed to training and mentoring of translational investigators and have an established record of recruiting and supporting women and minorities. The CEP will primarily assist junior faculty in their career development, but more established investigators interested in refocusing their research efforts on melanoma/skin cancer could also be considered. Women and underrepresented minorities will be strongly encouraged to participate. Likewise, projects aimed at addressing health disparities and/or skin cancer subtypes more common in underrepresented minorities will be encouraged and given special consideration. A team of clinicians, educators and researchers with broad expertise in translational research will ensure implementation of the specific aims of this program. With the support of the University of Pennsylvania, the Abramson Cancer Center and The Wistar Institute, the CEP will provide junior faculty the resources and guidance needed to establish innovative and fully funded independent skin cancer research programs and become future academic leaders. The CEP will provide awardees with two years of financial support for translational research projects in skin cancer with potential promotion to full SPORE projects or independent grant support. Awardees are required to actively participate in SPORE functions, use the SPORE Core resources, and provide both formal written progress reports and oral presentations. We have established high standards and expectations for the research mentors and a formalized program of long-term awardee mentorship. The program measures success by resulting publications, funding, and ultimately career advancement and national recognition. We have an outstanding talent pool of candidates and an effective training and mentorship program that will result in an exceptional group of skin cancer researchers. Our SPORE CEP has had an outstanding record recruiting and training investigators for careers in translational skin cancer research. Our past CEP awardees have published 74 papers during the past cycle and have been highly successful in obtaining peer reviewed funding from NCI and/or other funding agencies. In addition, all past awardees have transitioned from young investigators into leading academic positions and remain in the skin cancer field.
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Targeting S6K2 to Overcome Drug Resistance in NRAS-mutant Melanoma
  • 批准号:
    10539830
  • 项目类别:
  • 资助金额:
    $52.28万
  • 财政年份:
    2022
  • 负责人:
    Jessie Villanueva
  • 依托单位:
Career Enhancement Program
  • 批准号:
    10268748
  • 项目类别:
  • 资助金额:
    $8.51万
  • 财政年份:
    2021
  • 负责人:
    Jessie Villanueva
  • 依托单位:
Targeting TERT in Melanoma
  • 批准号:
    10247101
  • 项目类别:
  • 资助金额:
    $4.9万
  • 财政年份:
    2017
  • 负责人:
    Jessie Villanueva
  • 依托单位:
Administrative Core
  • 批准号:
    10733193
  • 项目类别:
  • 资助金额:
    $7.92万
  • 财政年份:
    2017
  • 负责人:
    Jessie Villanueva
  • 依托单位:
海外基金