Aging and Alzheimer's Research Training

衰老和阿尔茨海默氏症研究培训

• 批准号: 10483115
• 负责人: G WILLIAM REBECK
• 金额: $ 51.59万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10483115
• 关键词: Aging; Alzheimer' s Disease; Research Training

The Georgetown University “Aging and Alzheimer’s Research Training” (AART) program is designed for predoctoral students and postdoctoral fellows whose backgrounds have not included substantial previous training in aging or Alzheimer’s disease. It is driven by a transdisciplinary group of researchers across biomedical topics that are associated with cognitive impairment with aging (e.g., diabetes, HIV-infection, traumatic brain injury, proteinopathies, chemotherapy, seizures). The AART program will direct aspects of these research disciplines more directly to aging and AD research through the trainees. Participating faculty have the dedicated time and the University support to allow the AART program to thrive. Beyond this research, there are ten general areas of required training: 1) Clinical exposures in the Memory Disorders Program and in brain cuttings; 2) Coursework in areas of Biostatistics, Aging, and Neurodegeneration; 3) Structured personal interactions each semester with researchers from Alzheimer’s Disease Research Centers; 4) Intensive grant writing for current research projects and nascent careers; 5) Attendance and presentations at national meetings; 6) A new Georgetown symposium on Aging and Alzheimer’s disease; 7) Cohort writing of a review paper on an interdisciplinary research topic; 8) Regular training the Responsible Conduct of Research as well as Rigor and Reproducibility; 9) Roundtables to promote thoughtful consideration of training experiences, including research; and 10) Outreach experiences for public education and social good. As developed, several of these required activities are specific to the AART cohorts (e.g., personal interactions with national research leaders, instruction in writing of a publishable literature review, data presentations), and several more would positively impact the broader Washington, DC research community (the yearly Aging and AD symposium; research interactions with regional Alzheimer’s Disease Research Centers). Other activities ensure that trainees benefit from current University resources (journal clubs, existing coursework, training in quantitative and reproducible data analysis). Trainees will work with the Office of Career Strategy and Professional Development, which will also aid in the recruitment of individuals from under-represented minority groups. The program is directed by G. William Rebeck, who has contributed research to these areas for nearly 30 years. Oversight is provided by an Executive Committee, and by Internal and External Advisory Boards. Georgetown has the advantages of a cohesive set of researchers and strong financial support from the University. Furthermore, there are resources in the Washington DC area that are unique for better training, including researchers at the NIH/NIA, Howard University programs, and federal interactions. The goal of the AART is to take strong existing research programs at Georgetown related to conditions of aging, and use them to train students and fellows more intentionally in topics of aging and AD. This program will also drive these research labs to produce impactful aging and AD research.

乔治城大学的“老龄化和阿尔茨海默氏症研究培训”（AART）计划是专为 博士前学生和博士后研究员的背景没有包括大量的以前 关于衰老或阿尔茨海默病的训练。它是由一个跨学科的研究小组推动的， 与随着衰老的认知障碍相关的生物医学主题（例如，糖尿病，艾滋病病毒感染， 创伤性脑损伤、蛋白质病、化疗、癫痫发作）。AART计划将指导以下方面 这些研究学科更直接地通过受训者进行老龄化和AD研究。参与教师 有专门的时间和大学的支持，让AART计划蓬勃发展。除了这项研究， 有10个一般领域的必要培训：1）临床暴露在记忆障碍计划和 脑切片; 2）生物统计学，衰老和神经退行性疾病领域的课程; 3）结构化的个人 每学期与阿尔茨海默病研究中心的研究人员进行互动; 4）密集资助 为当前的研究项目和新生的职业写作; 5）出席国家级会议并发表演讲 会议; 6）一个新的乔治城研讨会上老化和阿尔茨海默氏病; 7）队列撰写的评论 关于跨学科研究主题的论文; 8）定期培训负责任的研究行为以及 9）圆桌会议，促进对培训经验的深思熟虑， 包括研究;和10）公共教育和社会公益的外联经验。作为发达国家， 这些所需的活动中的一部分是特定于AART队列的（例如，个人与国家研究的互动 领导人，指导撰写可追溯的文献综述，数据演示），还有几个将 积极影响更广泛的华盛顿，DC研究社区（年度老龄化和AD研讨会; 与区域阿尔茨海默病研究中心的研究互动）。其他活动确保 学员受益于目前的大学资源（期刊俱乐部，现有的课程，定量培训， 和可再现的数据分析）。受训人员将与职业战略和专业人员办公室合作， 这也将有助于从代表性不足的少数群体中征聘个人。的 程序由G.威廉·斯派克在这些领域的研究已经有近30年了。 监督由执行委员会以及内部和外部咨询委员会提供。乔治敦 拥有一批有凝聚力的研究人员和来自大学的强大财政支持。 此外，在华盛顿地区，有一些独特的资源可以提供更好的培训，包括 NIH/NIA、霍华德大学项目和联邦互动的研究人员。AART的目标是 利用乔治敦大学现有的与衰老有关的研究项目， 学生和研究员更有意识地在老龄化和AD的主题。该计划还将推动这些研究 实验室进行有影响力的衰老和AD研究。