Aging and Alzheimer's Research Training

衰老和阿尔茨海默氏症研究培训

• 批准号: 10483115
• 负责人: G WILLIAM REBECK
• 金额: $ 51.59万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10483115
• 关键词: Aging; Alzheimer' s Disease; Research Training

The Georgetown University “Aging and Alzheimer’s Research Training” (AART) program is designed for predoctoral students and postdoctoral fellows whose backgrounds have not included substantial previous training in aging or Alzheimer’s disease. It is driven by a transdisciplinary group of researchers across biomedical topics that are associated with cognitive impairment with aging (e.g., diabetes, HIV-infection, traumatic brain injury, proteinopathies, chemotherapy, seizures). The AART program will direct aspects of these research disciplines more directly to aging and AD research through the trainees. Participating faculty have the dedicated time and the University support to allow the AART program to thrive. Beyond this research, there are ten general areas of required training: 1) Clinical exposures in the Memory Disorders Program and in brain cuttings; 2) Coursework in areas of Biostatistics, Aging, and Neurodegeneration; 3) Structured personal interactions each semester with researchers from Alzheimer’s Disease Research Centers; 4) Intensive grant writing for current research projects and nascent careers; 5) Attendance and presentations at national meetings; 6) A new Georgetown symposium on Aging and Alzheimer’s disease; 7) Cohort writing of a review paper on an interdisciplinary research topic; 8) Regular training the Responsible Conduct of Research as well as Rigor and Reproducibility; 9) Roundtables to promote thoughtful consideration of training experiences, including research; and 10) Outreach experiences for public education and social good. As developed, several of these required activities are specific to the AART cohorts (e.g., personal interactions with national research leaders, instruction in writing of a publishable literature review, data presentations), and several more would positively impact the broader Washington, DC research community (the yearly Aging and AD symposium; research interactions with regional Alzheimer’s Disease Research Centers). Other activities ensure that trainees benefit from current University resources (journal clubs, existing coursework, training in quantitative and reproducible data analysis). Trainees will work with the Office of Career Strategy and Professional Development, which will also aid in the recruitment of individuals from under-represented minority groups. The program is directed by G. William Rebeck, who has contributed research to these areas for nearly 30 years. Oversight is provided by an Executive Committee, and by Internal and External Advisory Boards. Georgetown has the advantages of a cohesive set of researchers and strong financial support from the University. Furthermore, there are resources in the Washington DC area that are unique for better training, including researchers at the NIH/NIA, Howard University programs, and federal interactions. The goal of the AART is to take strong existing research programs at Georgetown related to conditions of aging, and use them to train students and fellows more intentionally in topics of aging and AD. This program will also drive these research labs to produce impactful aging and AD research.

乔治敦大学“老化和阿尔茨海默氏症的研究培训”（AART）计划是为 背景的学生和博士后研究员的背景尚未包括以前的实质性 接受衰老或阿尔茨海默氏病的培训。它是由一群跨学科研究人员驱动的 与衰老的认知障碍相关的生物医学主题（例如糖尿病，HIV感染， 创伤性脑损伤，蛋白质病，化学疗法，癫痫发作）。 AART计划将指导 这些研究更直接地通过培训来实现衰老和广告研究。参与教师 有专门的时间和大学的支持，以使AART计划得以蓬勃发展。除了这项研究之外， 需要培训的十个一般领域：1）记忆障碍计划中的临床暴露 大脑插条； 2）生物统计学，衰老和神经退行性领域的课程； 3）结构化个人 每个学期与阿尔茨海默氏病研究中心的研究人员进行互动； 4）密集赠款 为当前的研究项目和新生的职业写作； 5）参加国家的出席和演讲 会议； 6）关于衰老和阿尔茨海默氏病的新乔治敦研讨会； 7）评论的队列写作 跨学科研究主题的论文； 8）定期培训负责任的研究行为 严格和可重复性； 9）圆桌会议以促进对培训经验的周到考虑， 包括研究； 10）公共教育和社会利益的外展经验。如开发，几个 这些必需的活动中有特定于AART队列（例如，与国家研究的个人互动 领导者，可发表文献综述的书面指示，数据演示）等等 积极影响更广泛的华盛顿特区研究社区（年度老化和AD研讨会； 研究与阿尔茨海默氏病研究中心的研究相互作用）。其他活动确保 受训者从当前的大学资源中受益（期刊俱乐部，现有课程，定量培训 和可再现数据分析）。学员将与职业战略和专业办公室合作 发展，这也将有助于从代表性不足的少数群体中招募个人。这 计划由G. William Rebeck执导，他为这些地区贡献了近30年的研究。 监督由执行委员会以及内部和外部咨询委员会提供。乔治敦 具有一组凝聚力的研究人员和大学的大力财政支持的优势。 此外，华盛顿特区还有一些资源，可以进行更好的培训，包括 NIH/NIA，霍华德大学计划和联邦互动的研究人员。 AART的目标是 在乔治敦（Georgetown）进行与衰老条件有关的强大现有研究计划 学生和研究员更有意地涉及衰老和广告的主题。该计划还将推动这些研究 实验室生产有影响力的衰老和广告研究。