Aging and Alzheimer's Research Training

衰老和阿尔茨海默氏症研究培训

• 批准号: 10187377
• 负责人: G WILLIAM REBECK
• 金额: $ 21.81万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10187377
• 关键词: Aging; Alzheimer' s Disease; Research Training

The Georgetown University “Aging and Alzheimer’s Research Training” (AART) program is designed for predoctoral students and postdoctoral fellows whose backgrounds have not included substantial previous training in aging or Alzheimer’s disease. It is driven by a transdisciplinary group of researchers across biomedical topics that are associated with cognitive impairment with aging (e.g., diabetes, HIV-infection, traumatic brain injury, proteinopathies, chemotherapy, seizures). The AART program will direct aspects of these research disciplines more directly to aging and AD research through the trainees. Participating faculty have the dedicated time and the University support to allow the AART program to thrive. Beyond this research, there are ten general areas of required training: 1) Clinical exposures in the Memory Disorders Program and in brain cuttings; 2) Coursework in areas of Biostatistics, Aging, and Neurodegeneration; 3) Structured personal interactions each semester with researchers from Alzheimer’s Disease Research Centers; 4) Intensive grant writing for current research projects and nascent careers; 5) Attendance and presentations at national meetings; 6) A new Georgetown symposium on Aging and Alzheimer’s disease; 7) Cohort writing of a review paper on an interdisciplinary research topic; 8) Regular training the Responsible Conduct of Research as well as Rigor and Reproducibility; 9) Roundtables to promote thoughtful consideration of training experiences, including research; and 10) Outreach experiences for public education and social good. As developed, several of these required activities are specific to the AART cohorts (e.g., personal interactions with national research leaders, instruction in writing of a publishable literature review, data presentations), and several more would positively impact the broader Washington, DC research community (the yearly Aging and AD symposium; research interactions with regional Alzheimer’s Disease Research Centers). Other activities ensure that trainees benefit from current University resources (journal clubs, existing coursework, training in quantitative and reproducible data analysis). Trainees will work with the Office of Career Strategy and Professional Development, which will also aid in the recruitment of individuals from under-represented minority groups. The program is directed by G. William Rebeck, who has contributed research to these areas for nearly 30 years. Oversight is provided by an Executive Committee, and by Internal and External Advisory Boards. Georgetown has the advantages of a cohesive set of researchers and strong financial support from the University. Furthermore, there are resources in the Washington DC area that are unique for better training, including researchers at the NIH/NIA, Howard University programs, and federal interactions. The goal of the AART is to take strong existing research programs at Georgetown related to conditions of aging, and use them to train students and fellows more intentionally in topics of aging and AD. This program will also drive these research labs to produce impactful aging and AD research.

乔治敦大学的“老龄化和阿尔茨海默氏症研究培训”(AART)计划是为 博士后研究生和博士后研究员，其背景不包括 在老龄化或阿尔茨海默氏症方面的培训。它是由一个跨学科的研究小组推动的 与衰老导致的认知障碍相关的生物医学主题(例如，糖尿病、艾滋病毒感染、 创伤性脑损伤、蛋白质病、化疗、癫痫)。AART计划将指导以下方面 这些研究学科更直接地通过受训者来研究衰老和AD。参会教职员工 有专门的时间和大学的支持，让AART项目蓬勃发展。在这项研究之外， 有十个需要培训的一般领域：1)记忆障碍计划和 脑部切割；2)生物统计学、衰老和神经退化学领域的课程；3)结构化的个人 每学期与阿尔茨海默病研究中心的研究人员互动；4)强化助学金 为当前的研究项目和新的职业生涯撰写文章；5)出席并在国家 会议；6)乔治敦大学关于老龄化和阿尔茨海默病的新研讨会；7)一篇评论的队列写作 关于跨学科研究主题的论文；8)定期培训负责任的研究行为 作为严谨性和可复制性；9)圆桌会议，以促进对培训经验的深思熟虑， 包括研究；10)公共教育和社会公益的推广经验。随着发展，有几个 这些必要的活动中，有专门针对AART队列的(例如，与国家研究的个人互动 领导人、撰写可发表的文献综述的指导、数据演示)，以及其他几个人将 积极影响更广泛的华盛顿特区研究界(每年的老龄化和AD专题讨论会； 与地区阿尔茨海默病研究中心的研究互动)。其他活动确保 受训者受益于当前的大学资源(期刊俱乐部、现有课程、量化培训 和可重现的数据分析)。受训人员将与职业战略和专业人员办公室合作 这也将有助于从代表性不足的少数群体中招募个人。这个 该项目由G.William Rebeck指导，他对这些领域的研究做出了近30年的贡献。 监督由执行委员会以及内部和外部咨询委员会提供。乔治敦大学 拥有一批有凝聚力的研究人员和来自大学的强大资金支持。 此外，华盛顿特区地区有独特的资源可用于更好的培训，包括 NIH/NIA、霍华德大学项目和联邦互动的研究人员。AART的目标是 参加乔治敦大学现有的与衰老状况相关的强大研究项目，并将其用于培训 学生和研究员更有意识地讨论老龄化和AD的话题。这一计划也将推动这些研究 实验室进行有影响力的衰老和AD研究。