Administrative Core

行政核心

• 批准号: 10487471
• 负责人: Marjan Boerma
• 金额: $ 65.43万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-24 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10487471
• 关键词: Address; Adverse effects; Advisory Committees; Animals; Applications Grants; Area; Arkansas; Cancer Patient; Cancer Survivor; Centers of Research Excellence; Communication; Discipline; Doctor of Philosophy; Ensure; Environment; Evaluable Disease; Evaluation; Fees; Funding; Goals; Grant; Growth; Immune response; Infrastructure; Institution; Interdisciplinary Study; Intestines; Journals; Life; Malignant Neoplasms; Manuscripts; Medical; Mentors; Methods; Occupational activity of managing finances; Oncology; Patients; Peer Review; Persons; Phase; Pilot Projects; Program Development; Publications; Quality of life; Radiation Injuries; Research; Research Personnel; Role; Schedule; Science; Scientist; Series; Services; Structure; Survivors; Teacher Professional Development; Toxic effect; Toxicology; Translational Research; Universities; Writing; cancer therapy; design; disability; experience; improved; irradiation; meetings; multidisciplinary; novel strategies; operation; prevent; programs; recruit; side effect; success; synergism

PROJECT SUMMARY/ABSTRACT Many cancer patients and survivors suffer from adverse effects due to treatment that can arise both during and after the completion of cancer therapy. The COBRE Center for Studies of Host Response to Cancer Therapy supports investigators from various disciplines who 1) research the mechanisms by which cancer therapy causes adverse effects, 2) identify new methods for detecting side effects sooner, and 3) develop novel strategies to prevent or reduce side effects. The purpose of the Administrative Core (Core A) is to build a self-sustaining research Center by maximizing opportunities for investigators to succeed and by promoting interactions and synergy within the Center and with other research units in the institution. Core A will provide an efficient, integrated administrative infrastructure for the COBRE Center (Aim 1), accelerate scientific growth through faculty development and scientific advising (Aim 2), and expand and advance the Center toward self- sustainability (Aim 3). A primary function of the core is to provide administrative support for project leaders and to manage financial affairs for the Center as a whole. Core A ensures there is effective communication within and among the projects and cores. Additionally, the core provides the infrastructure for scientific advising and faculty development, which will encourage scientific progress for project leaders and will help integrate their efforts with those of other scientists on campus. With assistance of the External Advisory Committee, new project leaders will be recruited and selected to replace those who graduate from COBRE advisee status. The Center also will perform a systematic, objective evaluation of activities, project leaders and their research, scientific advising and faculty development programs, and core functions. This strategy will ensure the long-term success of the Center as an independent but well-integrated investigative unit on campus with a vibrant and synergistic research environment that comprehensively addresses the short-term and long-term side effects of cancer therapy.

项目总结/摘要 许多癌症患者和幸存者由于治疗而遭受不利影响，这些治疗可能在治疗期间出现， 以及癌症治疗结束后。COBRE癌症治疗宿主反应研究中心 支持来自不同学科的研究人员，他们1）研究癌症治疗导致 不良反应，2）更快地发现新的检测副作用的方法，3）开发新的策略， 预防或减少副作用。行政核心（核心A）的目的是建立一个自我维持的 研究中心通过最大限度地提高研究人员成功的机会，并通过促进互动， 中心内部以及与该机构其他研究单位的协同作用。核心A将提供一个高效， COBRE中心的综合管理基础设施（目标1），通过 教师发展和科学咨询（目标2），并扩大和推进中心向自我， 可持续性（目标3）。核心小组的一项主要职能是为项目领导人提供行政支助， 管理中心的财务。核心A确保内部有效沟通 在项目和核心之间。此外，核心还为科学咨询提供基础设施， 教师发展，这将鼓励项目领导人的科学进步，并将有助于整合他们的 与校园里其他科学家的努力。在外部咨询委员会的协助下， 将招募和挑选领导人，以取代那些从COBRE毕业的学员。中心 还将对活动、项目负责人及其研究、科学研究、 咨询和教师发展计划，以及核心职能。这一战略将确保长期的成功 该中心作为一个独立的，但在校园内整合良好的调查单位与一个充满活力和协同 全面解决癌症短期和长期副作用的研究环境 疗法