Administrative Core

项目摘要/摘要 许多癌症患者和幸存者由于在两种情况下可能出现的治疗而遭受不良反应 并在癌症治疗完成后。科布雷癌症治疗宿主反应研究中心 支持来自不同学科的研究人员，他们1)研究癌症治疗引起的机制 不良反应，2)更快地确定检测副作用的新方法，以及3)开发新的战略，以 预防或减少副作用。行政核心(核心A)的目的是建立一个自我维持的 通过最大限度地增加研究人员的成功机会并通过促进互动和 中心内部以及与机构内其他研究单位的协同作用。核心A将提供高效、 科布雷中心的综合行政基础设施(目标1)，通过 教师发展和科学咨询(目标2)，并扩大和推进中心走向自我 可持续性(目标3)。核心的一个主要职能是为项目负责人和 负责中心的整体财务管理工作。核心A确保内部有效沟通 在这些项目和核心中。此外，该核心还为科学咨询和 教师发展，这将鼓励项目负责人的科学进步，并将有助于整合他们的 与校园里的其他科学家一起努力。在外部咨询委员会的协助下，新项目 将招聘和挑选领导人，以取代那些从科布雷顾问身份毕业的人。《中心》 还将对活动、项目负责人及其研究、科学进行系统、客观的评价 咨询和教师发展计划，以及核心职能。这一战略将确保长期的成功。 该中心是一个独立但整合良好的校园调查单位，具有活力和协同性 全面解决癌症短期和长期副作用的研究环境 心理治疗。

PROJECT SUMMARY/ABSTRACT Many cancer patients and survivors suffer from adverse effects due to treatment that can arise both during and after the completion of cancer therapy. The COBRE Center for Studies of Host Response to Cancer Therapy supports investigators from various disciplines who 1) research the mechanisms by which cancer therapy causes adverse effects, 2) identify new methods for detecting side effects sooner, and 3) develop novel strategies to prevent or reduce side effects. The purpose of the Administrative Core (Core A) is to build a self-sustaining research Center by maximizing opportunities for investigators to succeed and by promoting interactions and synergy within the Center and with other research units in the institution. Core A will provide an efficient, integrated administrative infrastructure for the COBRE Center (Aim 1), accelerate scientific growth through faculty development and scientific advising (Aim 2), and expand and advance the Center toward self- sustainability (Aim 3). A primary function of the core is to provide administrative support for project leaders and to manage financial affairs for the Center as a whole. Core A ensures there is effective communication within and among the projects and cores. Additionally, the core provides the infrastructure for scientific advising and faculty development, which will encourage scientific progress for project leaders and will help integrate their efforts with those of other scientists on campus. With assistance of the External Advisory Committee, new project leaders will be recruited and selected to replace those who graduate from COBRE advisee status. The Center also will perform a systematic, objective evaluation of activities, project leaders and their research, scientific advising and faculty development programs, and core functions. This strategy will ensure the long-term success of the Center as an independent but well-integrated investigative unit on campus with a vibrant and synergistic research environment that comprehensively addresses the short-term and long-term side effects of cancer therapy.