Rurality, tobacco use, and COPD: an analysis of two national datasets

农村、烟草使用和慢性阻塞性肺病：对两个国家数据集的分析

• 批准号: 10491256
• 负责人: LAURA Marie PAULIN
• 金额: $ 24.02万
• 依托单位: DARTMOUTH-HITCHCOCK CLINIC
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-20 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10491256
• 关键词: Address; American; Behavior; Belief; Benefits and Risks; Chronic Obstructive Pulmonary Disease; Cigarette; Data; Data Set; Disease Outcome; Electronic cigarette; Epidemiology; Exposure to; Future; Generations; Geographic Locations; Geography; Goals; Health; Incidence; Individual; Intervention; Location; Mission; Motivation; National Health Interview Survey; Outcome; Pattern; Perception; Population; Population Assessment of Tobacco and Health; Prevalence; Public Health; Research; Respiratory Signs and Symptoms; Risk; Risk Factors; Rural; Rural Population; Testing; Tobacco use; United States; United States National Institutes of Health; Urban Population; Vulnerable Populations; airway obstruction; base; cigarette smoking; disorder risk; experience; geographic difference; geographic disparity; health disparity; improved outcome; insight; regional difference; risk perception; rural area; rural residence; rurality; smoking cessation; social; tailored messaging; therapy design; tobacco exposure; tobacco products; trend

Project Abstract Individuals with chronic obstructive pulmonary disease (COPD) who live in rural areas of the United States have worse health outcomes compared with their non-rural counterparts. Although it is known that rural areas have higher rates of cigarette smoking, and that cigarette smoking is associated with worse outcomes in COPD, less is known about geographic variations in the motivations and beliefs that influence tobacco product appeal and use, especially among newer tobacco products including e-cigarettes. Further, it is largely unknown how much variability in tobacco use accounts for the geographic differences seen in COPD outcomes. Our long-term goal is to identify potentially modifiable determinants of tobacco product use that contribute to worse COPD in rural US, leading to future geographically tailored interventions designed to improve outcomes. Our overall objective for this application, which is the next step toward attainment of our long-term goal, is to quantify the perceptions of risk and benefit on the pattern of tobacco use in rural and urban populations in the United States, and to determine the impact of such patterns on COPD outcomes. Our central hypothesis is that perceptions of risk and benefit of tobacco products differ by geographic location in the US, and that tobacco exposure contributes significantly to the increased COPD risks associated with rural location. The rationale for this project is that identifying factors that influence tobacco product appeal and use will provide detailed insight into potentially modifiable contributors to geographic disparities in health outcomes and inform regulatory strategy. Using existing datasets, we will test our hypothesis in two specific aims: 1) To quantify and compare patterns of tobacco product use by geographic location, and to determine how perceptions of risk and benefit of tobacco products differ by geographic location; 2) To determine the relationship between geographic location and COPD prevalence, incidence, and respiratory symptoms, and to quantify the contribution of tobacco product exposure to these relationships. To address our aims, will use data from the Population Assessment of Tobacco and Health (PATH) Study and the National Health Interview Survey (NHIS).The PATH Study is a longitudinal, nationally representative study that includes detailed questions on the motivations, beliefs, and perceptions influencing tobacco product use, allowing us to analyze the longitudinal association of these trends with COPD risk and respiratory symptoms within a broad definition of urbanicity. In a separate, focused analysis, we will determine the cross-sectional association between tobacco products and COPD prevalence across urban/rural continuum using nationally representative data from the NHIS study. Our research team has extensive experience working with these datasets, each providing complimentary longitudinal and cross sectional perspectives to allow for comprehensive assessment of the contribution of tobacco use to observed disparities in COPD outcomes in rural populations.

项目摘要

项目成果

Childhood Cigarette Smoking and Risk of Chronic Obstructive Pulmonary Disease in Older U.S. Adults.

儿童时期吸烟与美国老年人患慢性阻塞性肺疾病的风险。

• DOI: 10.1164/rccm.202303-0476oc
• 发表时间: 2023
• 期刊: American journal of respiratory and critical care medicine
• 影响因子: 24.7
• 作者: Sargent,JamesD;Halenar,Michael;Steinberg,AlexanderW;Ozga,Jenny;Tang,Zhiqun;Stanton,CassandraA;Paulin,LauraM
• 通讯作者: Paulin,LauraM