Cancer Prevention and Control Program

癌症预防与控制 堪萨斯大学癌症中心的癌症预防和控制（CPC）研究项目 （KUCC）汇集了一个跨学科的研究人员团队，专注于：1）开发，测试， 实施创新战略，改变导致癌症风险和癌症差异的行为 发病率（人群水平的一级预防）; 2）确定生物标志物驱动的癌症机会 在患癌前疾病或遗传性癌症风险的高危人群中进行预防和检测 干预措施，以改善与癌症预防相关的风险生物标志物的检测和调节， 这些高危患者（高危预防）;和3）发展和传播行为，营养， 和临床支持干预措施，以解决癌症的影响（生存）。49名中共党员 来自6所学校的23个系。他们代表了丰富的专业知识，包括行为科学， 神经科学，初级保健，护理，肿瘤学，流行病学，经济学，转化生物学，药理学， 通信、生物统计和卫生服务研究。计划成员获得1330万美元的支持， 年度总资金，包括来自国家癌症研究所的380万美元。目前，69%的中国共产党党员是 主要研究人员在外部资助的癌症研究赠款。CPC方案活动支持内部 通过翻译研究研讨会，访问学者计划，以及 癌症护理提供和公平，烟草控制，实施科学和卫生服务研究 工作组。这些活动提高了方案内和方案间的生产力， 2020年中国共产党党员发表的文章，其中20%是跨计划的，32%是内部的， 67%的人有外部合作。 CPC的工作始于KUCC集水区的需要，也终于KUCC集水区的需要。中共党员表现出 我们在发展基础设施以进行癌症预防及控制研究方面， 农村地区，非洲裔美国人，西班牙裔和美洲印第安人社区和个人 刑事司法系统。一个强大的导师计划将重点放在培训上。七个CPC 仅在2020年，学员就获得了超过120万美元的校外培训补助金支持; CPC成员 CCSG发展基金的回报率为9.2倍，KUCC试点基金的回报率为23.3倍 项目CPC成员的共同工作导致：更好地了解癌症控制需求， KUCC集水区;提高分析受影响和风险人口需求的能力; 识别新的癌前模型和新的生物标志物;改进检测和预防的策略 高风险患者的癌症;设计和提供癌症预防和控制的更好战略 信息;以及改善烟草控制、癌症筛查、体育活动、肥胖和 在临床实践和社区层面的生存方案。

CANCER PREVENTION AND CONTROL: ABSTRACT The Cancer Prevention and Control (CPC) research program at The University of Kansas Cancer Center (KUCC) brings together an interdisciplinary team of researchers focused on: 1) developing, testing, and implementing innovative strategies to modify behaviors that drive cancer risk and disparities in cancer incidence (Population-Level Primary Prevention); 2) identifying biomarker-driven opportunities for cancer prevention among high-risk individuals with premalignant disease or hereditary cancer risk and testing interventions to improve detection and modulation of risk biomarkers associated with cancer prevention in these high-risk patients (High-Risk Prevention); and 3) developing and disseminating behavioral, nutritional, and clinical support interventions to address the impact of cancer (Survivorship). The 49 members of CPC come from 23 departments in six schools. They represent a rich mix of expertise, including behavioral science, neuroscience, primary care, nursing, oncology, epidemiology, economics, translational biology, pharmacology, communications, biostatistics, and health services research. Program members are supported by $13.3M in total annual funds, including $3.8M from the National Cancer Institute. Currently, 69% of CPC members are principal investigators on externally funded cancer research grants. CPC program activities support both intra- and inter-programmatic interactions through translational research seminars, a visiting scholar program, and cancer care delivery and equity, tobacco control, implementation science, and health services research working groups. These activities have fostered intra- and inter-programmatic productivity, resulting in 225 articles published by CPC members in 2020, of which 20% had inter-programmatic, 32% had intra- programmatic, and 67% had external collaborations. The work in CPC begins and ends with the needs of the KUCC catchment area. CPC members have shown remarkable success in developing the infrastructure to conduct cancer prevention and control research in our region among rural, African American, Hispanic, and American Indian communities and individuals in the criminal justice system. A strong mentorship program places a significant focus on training. Seven CPC trainees received more than $1.2M in extramural training grant support in 2020 alone; CPC members have demonstrated a 9.2-fold return from CCSG Developmental Funds and a 23.3-fold return from KUCC Pilot Projects. The shared work of CPC members has led to: a better understanding of the cancer control needs in the KUCC catchment area; improved capacity to analyze the needs of affected and at-risk populations; identification of novel pre-cancerous models and new biomarkers; improved strategies to detect and prevent cancer in high-risk patients; better strategies for the design and delivery of cancer prevention and control messages; and improved delivery of tobacco control, cancer screening, physical activity, obesity, and survivorship programs at the level of both the clinical practice and the community-at-large.