PTN, PHARMACEUTICALS (PK) AND SAFETY OF COMMONLY USED DRUGS IN LACTATING WOMEN AND BREASTFED INFANTS (CUDDLE 2.0) NETWORK

PTN、药品 (PK) 以及哺乳期妇女和母乳喂养婴儿常用药物的安全性 (CUDDLE 2.0) 网络

• 批准号: 10495378
• 负责人: KANECIA ZIMMERMAN
• 金额: $ 41.62万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2024-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10495378
• 关键词: Age; Anxiety; Azithromycin; Bacterial Infections; Blood; Breast Feeding; Breastfed infant; Child; Childhood; Ciprofloxacin; Clindamycin; Diabetes Mellitus; Dose; Doxycycline; Drug usage; Enrollment; Escitalopram; Fright; Human Milk; Hypertension; Infant; Labetalol; Lactation; Levaquin; Medical; Mental Depression; Metformin; Mothers; Nifedipine; Ondansetron; Oxycodone; Participant; Pharmaceutical Preparations; Research Personnel; Ritalin; Safety; Sampling; Sertraline; Symptoms; Tranexamic Acid; United States Food and Drug Administration; Woman; chronic pain; design; follow-up; off-patent; routine care

ClinicalTrials.gov Identifier: NCT03511118 This groundbreaking study, conducted by the PTN, is designed to assess the safety of commonly used off-patent medications when they are given to breastfeeding mothers. It is common for new mothers to have symptoms or medical conditions that must be treated with drugs. These mothers often struggle with their decision to take their medications because of the fear that the drugs will harm their children. With this study, PTN aims to find doses of commonly used drugs that are safe for both mothers and their breastfed infants. The Pediatric Trials Network (PTN) is undertaking a groundbreaking study to assess the safety of commonly used off-patent medications when they are given to breastfeeding mothers. The study will track how different drugs are passed through breastmilk to determine dosing levels that are safe for both mom and baby. Although the U.S. Food and Drug Administration

ClinicalTrials.gov标识符：NCT 03511118 这项由PTN进行的开创性研究旨在评估母乳喂养母亲常用的非专利药物的安全性。 这是常见的新妈妈有症状或医疗条件，必须用药物治疗。这些母亲经常挣扎着决定服用药物，因为担心药物会伤害他们的孩子。通过这项研究，PTN旨在找到对母亲和母乳喂养的婴儿都安全的常用药物剂量。 儿科试验网络（PTN）正在进行一项开创性的研究，以评估常用的非专利药物给母乳喂养的母亲时的安全性。该研究将跟踪不同药物如何通过母乳，以确定对母亲和婴儿都安全的剂量水平。尽管美国食品和药物管理局