Center for Dissemination and Implementation At Stanford (C-DIAS): Research Core

斯坦福大学传播与实施中心 (C-DIAS)：研究核心

• 批准号: 10493958
• 负责人: Lisa Saldana
• 金额: $ 57.05万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10493958
• 关键词: Acute; Address; Adoption; Behavior Therapy; COVID-19; Clinical; Communities; Community Health Systems; Community Practice; Complex; Conflict (Psychology); Dissemination and Implementation; Effectiveness; Ensure; Epidemic; Evidence based intervention; Evidence based practice; Foundations; Funding; Goals; Health Services Research; Healthcare Systems; Improve Access; Individual; Intervention; Knowledge; Laboratory Research; Learning; Measures; Methodology; Methods; Modeling; Monitor; Motivation; National Institute of Drug Abuse; Outcome; Patients; Persons; Pharmacological Treatment; Pharmacology; Policies; Positioning Attribute; Privatization; Process; Research; Research Methodology; Research Project Grants; Resource-limited setting; Resources; Scientific Advances and Accomplishments; Scientist; Standardization; Substance Use Disorder; System; Techniques; Time; Translating; Underrepresented Populations; United States National Institutes of Health; Variant; Work; addiction; community setting; contextual factors; cost; design; effective therapy; effectiveness clinical trial; ethnic minority; evidence base; flexibility; implementation evaluation; implementation facilitation; implementation measures; implementation process; implementation research; implementation science; implementation strategy; improved; innovation; instrument; marginalized population; member; model design; mortality; multidisciplinary; opioid use disorder; psychosocial; racial and ethnic; response; routine care; scale up; stimulant use; support tools; tool

C-DIAS RESEARCH CORE: PROJECT SUMMARY/ABSTRACT Improved access to evidence-based pharmacological and psychosocial treatments is urgently needed for persons with substance use disorders. Inequity in access to proven treatments is amplified in low-resourced communities and with organizations serving marginalized and underrepresented populations. The lack of rigor and consistency in methods, measures, design and approach undermines efforts to systematically learn how to implement evidence-based interventions across diverse settings. There is an enormous need for greater precision in how to implement and sustain proven interventions for addiction. Interventions and their delivery platforms are the “what” of an implementation endeavor, whereas implementation strategies are the “how” these interventions are installed and/or maintained. Only 2.4% of NIDA-funded research has examined the “how” of implementation strategies, and among these few, wide methodological variation exists. The Center for Dissemination & Implementation At Stanford (C-DIAS) Research Core integrates three teams of experts, led by top research scientists. The teams align with three domains necessary to advance implementation research in addiction: Methods & Measures, Design & Modeling, and Policy & Financing. Three complementary and innovative C-DIAS Research Projects will serve as open laboratories for Research Core activities. The Core will interact bi-directionally with the Research Projects, positioning each to accumulate and disseminate technical knowledge for the field. These synergistic efforts create an unprecedented opportunity for a deeper and accelerated examination of the mechanisms underlying how implementation strategies work, their contextual determinants, and how to select and deliver them to optimize implementation and clinical outcomes. The three Research Core teams, along with the Research Projects, will translate options about how to implement and at what cost for real-world decision-makers. The Research Core will: PREPARE the addiction research and practice communities with pragmatic and standardized methods and measures of implementation strategies for real-world implementation endeavors (Aim 1); IMPLEMENT rigorous examinations of the components and mechanisms of implementation strategies for effectiveness and cost, using innovative designs and modeling techniques, and creating decision-support tools for policymakers and systems leaders (Aim 2); and, SUSTAIN and scale-up evidence-based addiction treatments by identifying barriers, needed policy and financing strategies, and emerging solutions for ensuring their long-term, high quality and equitable delivery in community settings and health systems (Aim 3). Research Core activities directly address NIDA priorities to “better understand the barriers to successful and sustainable implementation of evidence-based practices and to develop implementation strategies that effectively overcome these barriers.” Not incremental, but instead paradigm shifting, the C-DIAS Research Core will add to the best of existing methodologies, and advance generalizable and practical innovations to improve equitable access to proven addiction treatments.

C-DIAS研究核心：项目总结/摘要 迫切需要改善获得循证药理学和心理社会治疗的机会， 物质使用障碍者。在资源匮乏的国家，获得经证实的治疗方面的不平等现象更为严重。 社区以及为边缘化和代表性不足的群体服务的组织。缺乏严谨性 方法、措施、设计和做法的一致性破坏了系统地学习如何 在不同环境中实施循证干预措施。有一个巨大的需求， 如何实施和维持行之有效的成瘾干预措施的精确性。干预措施及其实施 平台是实施奋进的“内容”，而实施战略是“方法” 安装和/或维护这些干预措施。只有2.4%的NIDA资助的研究检查了 执行战略的“如何”，以及在这几个方面，存在着广泛的方法差异。中心 传播与实施在斯坦福大学（C-DIAS）研究核心整合了三个专家团队，由 顶尖的研究科学家这些团队与推进实施研究所需的三个领域保持一致， 成瘾：方法与措施，设计与建模，政策与融资。三个互补， 创新的C-DIAS研究项目将作为研究核心活动的开放实验室。核心 将与研究项目进行双向互动，将每个项目定位为积累和传播 该领域的技术知识这些协同努力创造了前所未有的机会， 加速审查执行战略如何运作的基本机制， 背景决定因素，以及如何选择和提供它们，以优化实施和临床结果。 三个研究核心团队，沿着研究项目，将翻译有关如何 实现以及为现实世界决策者付出的代价。研究核心将：消除成瘾 研究和实践社区，具有务实和标准化的方法和执行措施 为现实世界的实施工作制定战略（目标1）; 实施战略的有效性和成本的组成部分和机制， 设计和建模技术，并为决策者和系统领导者创建决策支持工具 (Aim 2）;和，通过确定障碍，维持和扩大循证成瘾治疗，需要 政策和融资战略，以及确保其长期、高质量和公平 在社区环境和卫生系统中提供服务（目标3）。核心活动直接针对国家发展局 优先事项“更好地了解成功和可持续实施循证 ”我们必须采取有效措施，并制定有效克服这些障碍的实施战略。不是增量， 但是，C-DIAS研究核心将增加现有方法的最佳部分， 推进可推广和实用的创新，以改善公平获得经证实的成瘾治疗的机会。