Center for Dissemination and Implementation At Stanford (C-DIAS): Research Core

斯坦福大学传播与实施中心 (C-DIAS)：研究核心

• 批准号: 10493958
• 负责人: Lisa Saldana
• 金额: $ 57.05万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10493958
• 关键词: Acute; Address; Adoption; Behavior Therapy; COVID-19; Clinical; Communities; Community Health Systems; Community Practice; Complex; Conflict (Psychology); Dissemination and Implementation; Effectiveness; Ensure; Epidemic; Evidence based intervention; Evidence based practice; Foundations; Funding; Goals; Health Services Research; Healthcare Systems; Improve Access; Individual; Intervention; Knowledge; Laboratory Research; Learning; Measures; Methodology; Methods; Modeling; Monitor; Motivation; National Institute of Drug Abuse; Outcome; Patients; Persons; Pharmacological Treatment; Pharmacology; Policies; Positioning Attribute; Privatization; Process; Research; Research Methodology; Research Project Grants; Resource-limited setting; Resources; Scientific Advances and Accomplishments; Scientist; Standardization; Substance Use Disorder; System; Techniques; Time; Translating; Underrepresented Populations; United States National Institutes of Health; Variant; Work; addiction; community setting; contextual factors; cost; design; effective therapy; effectiveness clinical trial; ethnic minority; evidence base; flexibility; implementation evaluation; implementation facilitation; implementation measures; implementation process; implementation research; implementation science; implementation strategy; improved; innovation; instrument; marginalized population; member; model design; mortality; multidisciplinary; opioid use disorder; psychosocial; racial and ethnic; response; routine care; scale up; stimulant use; support tools; tool

C-DIAS RESEARCH CORE: PROJECT SUMMARY/ABSTRACT Improved access to evidence-based pharmacological and psychosocial treatments is urgently needed for persons with substance use disorders. Inequity in access to proven treatments is amplified in low-resourced communities and with organizations serving marginalized and underrepresented populations. The lack of rigor and consistency in methods, measures, design and approach undermines efforts to systematically learn how to implement evidence-based interventions across diverse settings. There is an enormous need for greater precision in how to implement and sustain proven interventions for addiction. Interventions and their delivery platforms are the “what” of an implementation endeavor, whereas implementation strategies are the “how” these interventions are installed and/or maintained. Only 2.4% of NIDA-funded research has examined the “how” of implementation strategies, and among these few, wide methodological variation exists. The Center for Dissemination & Implementation At Stanford (C-DIAS) Research Core integrates three teams of experts, led by top research scientists. The teams align with three domains necessary to advance implementation research in addiction: Methods & Measures, Design & Modeling, and Policy & Financing. Three complementary and innovative C-DIAS Research Projects will serve as open laboratories for Research Core activities. The Core will interact bi-directionally with the Research Projects, positioning each to accumulate and disseminate technical knowledge for the field. These synergistic efforts create an unprecedented opportunity for a deeper and accelerated examination of the mechanisms underlying how implementation strategies work, their contextual determinants, and how to select and deliver them to optimize implementation and clinical outcomes. The three Research Core teams, along with the Research Projects, will translate options about how to implement and at what cost for real-world decision-makers. The Research Core will: PREPARE the addiction research and practice communities with pragmatic and standardized methods and measures of implementation strategies for real-world implementation endeavors (Aim 1); IMPLEMENT rigorous examinations of the components and mechanisms of implementation strategies for effectiveness and cost, using innovative designs and modeling techniques, and creating decision-support tools for policymakers and systems leaders (Aim 2); and, SUSTAIN and scale-up evidence-based addiction treatments by identifying barriers, needed policy and financing strategies, and emerging solutions for ensuring their long-term, high quality and equitable delivery in community settings and health systems (Aim 3). Research Core activities directly address NIDA priorities to “better understand the barriers to successful and sustainable implementation of evidence-based practices and to develop implementation strategies that effectively overcome these barriers.” Not incremental, but instead paradigm shifting, the C-DIAS Research Core will add to the best of existing methodologies, and advance generalizable and practical innovations to improve equitable access to proven addiction treatments.

C-DIAS研究核心：项目摘要/摘要 迫切需要改善获得基于证据的药物和社会心理治疗的机会 患有药物使用障碍的人。在低资源中扩大了访问证明治疗的不平等现象 社区以及为边缘化和代表性不足的人群提供服务的组织。缺乏严格 以及方法，措施，设计和方法的一致性破坏了系统地学习如何学习的努力 在潜水员环境中实施基于证据的干预措施。对更大的需求很大 如何实施和维持成瘾的干预措施的精确性。干预及其交付 平台是实施努力的“内容”，而实施策略是“方式” 这些干预措施已安装和/或维护。只有2.4％的NIDA资助研究检查了 实施策略的“如何”以及在这几种方法中存在。中心 斯坦福大学（C-DIAS）研究核心的传播与实施核心集成了三个专家团队，由 顶级研究科学家。团队与提前实施研究所需的三个领域保持一致 成瘾：方法和措施，设计与建模以及政策与融资。三个完整和 创新的C-DIAS研究项目将作为研究核心活动的开放实验室。核心 将与研究项目进行双向互动，将每个项目定位为丙烯酸并传播 该领域的技术知识。这些协同的努力创造了一个前所未有的机会 并加速检查实施策略如何运作的机制 上下文确定词，以及如何选择和交付它们以优化实施和临床结果。 这三个研究核心团队以及研究项目将翻译有关如何 实施，并以现实世界中的决策者的成本为多少。研究核心将：准备成瘾 研究和实践社区采用务实和标准化的方法和实施措施 现实实施努力的策略（AIM 1）；进行严格的检查 使用创新的成本和实施策略的组件和机制 设计和建模技术，并为决策者和系统领导者创建决策支持工具 （目标2）;并且，通过识别障碍，所需的障碍来维持和扩展基于证据的成瘾治疗 政策和融资策略以及新兴解决方案，以确保其长期，高质量和公平 在社区环境和卫生系统中交付（AIM 3）。研究核心活动直接解决NIDA 优先考虑成功实施基于证据的成功和可持续实施的障碍 实践并制定有效克服这些障碍的实施策略。 但是相反，范式转移，C-DIAS研究核心将增加现有方法的最佳 提高可推广和实用的创新，以提高公平访问对成瘾的治疗。