Center for Dissemination and Implementation At Stanford (C-DIAS): Research Core

C-DIAS研究核心：项目摘要/摘要 迫切需要改善获得循证药理学和心理社会治疗的机会 有物质使用障碍的人。在资源匮乏的国家，在获得经过验证的治疗方法方面的不平等被放大 与社区和为边缘化和代表性不足的人口提供服务的组织合作。缺乏严谨性 方法、措施、设计和方法的一致性破坏了系统地学习如何 在不同环境中实施循证干预。有巨大的需求需要更大的 如何实施和维持行之有效的成瘾干预措施。干预措施及其交付 平台是实现工作的“什么”，而实现策略是“如何” 安装和/或维护这些干预措施。只有2.4%的NIDA资助的研究检查了 实施战略的“如何”，在这少数几个战略中，存在着广泛的方法差异。该中心为 斯坦福大学传播与实施(C-DIAS)研究核心整合了三个专家团队，由 顶尖的研究科学家。团队与推进实施研究所需的三个领域保持一致 上瘾：方法与措施、设计与建模、政策与融资。三个相辅相成的 创新的C-DIAS研究项目将作为研究核心活动的开放实验室。《核心》 将与研究项目进行双向互动，将每个项目定位为积累和传播 该领域的技术知识。这些协同努力为更深层次的合作创造了前所未有的机会 并加快对实施战略如何运作的机制的审查，其 背景决定因素，以及如何选择和交付它们，以优化实施和临床结果。 三个研究核心团队，以及研究项目，将翻译关于如何 以及对现实世界的决策者来说，成本是多少。研究核心意志：为上瘾做好准备 用务实、规范的实施方法和措施研究和实践社区 实际执行工作战略(目标1)；严格审查 实施成效和成本战略的组成部分和机制，使用创新 设计和建模技术，并为决策者和系统领导者创建决策支持工具 (目标2)；通过确定需要的障碍，维持和扩大循证成瘾治疗 政策和融资战略，以及确保其长期、高质量和公平的新兴解决方案 在社区环境和卫生系统中提供服务(目标3)。研究核心活动直接针对NIDA 优先事项：“更好地了解成功和可持续地执行循证政策的障碍 并制定有效克服这些障碍的执行战略。“不是递增的， 但不是范式的转变，C-DIAS研究核心将增加现有方法的最好部分，并且 推进可推广和实用的创新，以改善公平获得已证实的成瘾治疗的机会。

C-DIAS RESEARCH CORE: PROJECT SUMMARY/ABSTRACT Improved access to evidence-based pharmacological and psychosocial treatments is urgently needed for persons with substance use disorders. Inequity in access to proven treatments is amplified in low-resourced communities and with organizations serving marginalized and underrepresented populations. The lack of rigor and consistency in methods, measures, design and approach undermines efforts to systematically learn how to implement evidence-based interventions across diverse settings. There is an enormous need for greater precision in how to implement and sustain proven interventions for addiction. Interventions and their delivery platforms are the “what” of an implementation endeavor, whereas implementation strategies are the “how” these interventions are installed and/or maintained. Only 2.4% of NIDA-funded research has examined the “how” of implementation strategies, and among these few, wide methodological variation exists. The Center for Dissemination & Implementation At Stanford (C-DIAS) Research Core integrates three teams of experts, led by top research scientists. The teams align with three domains necessary to advance implementation research in addiction: Methods & Measures, Design & Modeling, and Policy & Financing. Three complementary and innovative C-DIAS Research Projects will serve as open laboratories for Research Core activities. The Core will interact bi-directionally with the Research Projects, positioning each to accumulate and disseminate technical knowledge for the field. These synergistic efforts create an unprecedented opportunity for a deeper and accelerated examination of the mechanisms underlying how implementation strategies work, their contextual determinants, and how to select and deliver them to optimize implementation and clinical outcomes. The three Research Core teams, along with the Research Projects, will translate options about how to implement and at what cost for real-world decision-makers. The Research Core will: PREPARE the addiction research and practice communities with pragmatic and standardized methods and measures of implementation strategies for real-world implementation endeavors (Aim 1); IMPLEMENT rigorous examinations of the components and mechanisms of implementation strategies for effectiveness and cost, using innovative designs and modeling techniques, and creating decision-support tools for policymakers and systems leaders (Aim 2); and, SUSTAIN and scale-up evidence-based addiction treatments by identifying barriers, needed policy and financing strategies, and emerging solutions for ensuring their long-term, high quality and equitable delivery in community settings and health systems (Aim 3). Research Core activities directly address NIDA priorities to “better understand the barriers to successful and sustainable implementation of evidence-based practices and to develop implementation strategies that effectively overcome these barriers.” Not incremental, but instead paradigm shifting, the C-DIAS Research Core will add to the best of existing methodologies, and advance generalizable and practical innovations to improve equitable access to proven addiction treatments.