Research Coordinating Center to Reduce Disparities in Multiple Chronic Diseases (RCC RD-MCD)

减少多种慢性疾病差异的研究协调中心 (RCC RD-MCD)

• 批准号: 10494165
• 负责人: Edwin Duncan Charlebois
• 金额: $ 450万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10494165
• 关键词: Affect; African American; Alaska Native; Asian Pacific Islander; COVID-19; California; Chronic; Chronic Disease; Cities; Clinical Trials Data Monitoring Committees; Clinical Trials Design; Collaborations; Collection; Common Data Element; Communication; Communities; Community Networks; Community of Practice; Country; Data; Data Science; Development; Educational workshop; Evaluation; Funding; Geography; Goals; Health; Health Disparities Research; Health Sciences; Health system; Hispanic; Homelessness; Individual; Institutes; Intervention; Intervention Trial; Latino; Mentors; Methods; Minority-Serving Institution; Monitor; National Institute on Minority Health and Health Disparities; Native Americans; Persons; PhenX Toolkit; Population; Prevention; Records; Research; Research Design; Research Personnel; Resource Sharing; Resources; San Francisco; Secure; Sexual and Gender Minorities; Site; Standardization; Statistical Data Interpretation; Systems Integration; Underserved Population; United States National Institutes of Health; Universities; Vulnerable Populations; biomedical informatics; community engaged research; community engagement; community partnership; comorbidity; data management; data sharing; data standards; data warehouse; design; disease disparity; disparity reduction; experience; flexibility; gender minority group; human subject; implementation science; instrument; meetings; member; minority health disparity; operation; programs; response; skill acquisition; skills; social health determinants; socioeconomics; tool; web site; webinar; working group

SUMMARY Significant disparities in prevention, treatment, and management of multiple chronic diseases exist along intersecting racial, cultural, socio-economic, and vulnerable population contextual lines; community engagement and culturally informed multilevel approaches are required to effectively reduce these disparities. The UCSF Research Coordinating Center will leverage and pivot our significant expertise, experience, and capacity in community-engaged research, disparities research, program implementation experience with underserved and vulnerable populations, data science, and major chronic diseases to serve and support a nationwide research coordinating and technical assistance center. The Specific Aims of the project are to: 1) Develop the NIMHD RD-MCD Research Consortium and its Oversight Mechanisms: through the Organizational and Management Unit’s convening, secure communication, internal and external resource sharing, standardization, progress, site, and study monitoring, and dissemination functions via a 508- compliant consortium website in cooperation with program officials, representative Steering Committee, networked Community Advisory Boards, and an independent Data and Safety Monitoring Board (DSMB). 2) Implement RD-MCD Consortium-wide Common Data Element Development, Collection, Integration, Curation, Analysis, and Sharing using existing well-developed national data coordinating and collection center resources and expertise forming a Research Coordination & Data Management (RCDM) Unit providing a secure and accessible data warehouse hub for RD-MCD Consortium data, and technical assist- ance and guidance on: implementing multiple data standards and cross-study instruments including PhenX toolkit collections (e.g. Social Determinants of Health (SDOH)); and up-to-date RD-MCD information, tools, and resources via secured investigator-facing and community-facing website resource pages. 3) Establish a Multiple Chronic Diseases Disparities (MCD) Research Educational Development Network: facilitated by the Skills Development Unit combining scientific, networking, and skills building expertise across the P50 MCD research consortium to implement and maintain diverse development opportunities for academic researchers, minority-serving institutions, health workers, and other community partners. The RCC will deliver and coordinate: a) monthly webinars, b) yearly skills development workshops, c) access to mentors across the MCD consortium and the NIH National Research Mentoring Network, and d) track the impact of the RCC and Center’s development activities. 4) Facilitate and Monitor Vibrant Community-Engaged Research among NIMHD RD-MCD P50 Research Consortium members and community partners through a Community Engagement (CE) Unit providing access to underserved/vulnerable population-specific Technical Assistance (TA) teams, structural and organizational support for a Community of Practice, and collaborative Scientific Working Groups.

概括 多种慢性病的预防、治疗和管理存在显着差异 种族、文化、社会经济和弱势群体背景线的交叉；社区 为了有效减少这些差异，需要采取参与和了解文化的多层次方法。 加州大学旧金山分校研究协调中心将利用和利用我们重要的专业知识、经验和 社区参与研究的能力、差异研究、项目实施经验 服务不足和弱势群体、数据科学和主要慢性病，以服务和支持 全国研究协调和技术援助中心。该项目的具体目标是： 1) 发展 NIMHD RD-MCD 研究联盟及其监督机制：通过 组织和管理单位的召集、安全沟通、内部和外部资源 第508章 508 与项目官员、代表指导委员会合作的合规联盟网站， 网络化社区咨询委员会以及独立的数据和安全监控委员会 (DSMB)。 2) 实施 RD-MCD 联盟范围内的通用数据元素开发、收集、集成、 利用现有完善的国家数据协调和收集进行管理、分析和共享 中心资源和专业知识形成研究协调和数据管理（RCDM）部门 为 RD-MCD 联盟数据提供安全且可访问的数据仓库中心，并提供技术支持 实施多个数据标准和交叉研究工具（包括 PhenX）的支持和指导 工具包集合（例如健康的社会决定因素（SDOH））；以及最新的 RD-MCD 信息、工具、 和资源通过安全的面向调查员和面向社区的网站资源页面。 3）建立多种慢性病差异（MCD）研究教育发展 网络：由技能发展部门推动，结合科学、网络和技能建设 P50 MCD 研究联盟的专业知识，以实施和维持多元化发展 为学术研究人员、少数民族服务机构、卫生工作者和其他社区提供机会 合作伙伴。 RCC 将提供和协调：a) 每月网络研讨会，b) 年度技能开发 研讨会，c) 获得 MCD 联盟和 NIH 国家研究指导的导师 网络，以及 d) 跟踪 RCC 和中心发展活动的影响。 4) 促进和监督 NIMHD RD-MCD P50 研究中充满活力的社区参与研究 联盟成员和社区合作伙伴通过社区参与 (CE) 单位提供 获得服务不足/弱势群体特定的技术援助 (TA) 团队、结构和 对实践社区和协作科学工作组的组织支持。