Investigator Development Core

项目摘要 深南中心减少慢性病差异的使命是促进健康公平 并减少美国“深南”地区的心脏代谢疾病负担， 包括亚拉巴马、密西西比和路易斯安那。完成这一使命的一个关键组成部分是不断增长， 使劳动力多样化，使其具备进行与传播有关的研究所需的专门知识， 实施，比较有效性，并将循证干预措施转化为现实世界 设置.研究者发展核心的主要目标是准备和指导研究者， 发展创新的研究，应用精确的公共卫生方法-最好被视为“提供 在正确的时间对正确的人群进行正确的干预”-通过仔细注意环境因素， 多层次（个人、人际、组织社区、社会）。为此，我们召集了 一个跨学科的研究人员团队，具有来自四个学术领域的翻译研究专业知识。 合作机构（亚拉巴马大学伯明翰分校、彭宁顿生物医学研究中心、 密西西比大学医学中心和塔斯基吉大学）以及社区利益相关者 致力于解决该地区心脏代谢疾病的差异。研究者负责人 发展核心，与中心的共同主任和其他核心教师一起，制定了一个强有力的计划 为早期研究人员提供翻译研究方法方面的独特培训，并获得核心 专门用于这项工作所必需的主题的资源。研究者发展核心将建立一个 竞争性试点研究计划，每年至少资助六个高质量的研究项目， 将为赠款学员提供一个指导小组，为推进试点提供战略和援助 研究到竞争性赠款申请。研究者发展核心还将提供访问子 单位，将提供试点获奖者，以及三个中心项目，专业知识，在翻译设计和 方法、社区参与性研究、执行和传播科学、成本效益 和评估健康的社会决定因素。最终，这些活动将产生30至40个早期职业生涯 研究者，允许跨学术/研究机构进行协作和集中的心脏代谢研究 深入南方的机构，并确保地方/区域社区环境的参与。关键 这一核心的成果包括出版物和来自试点奖的校外赠款，职业 获奖者的轨迹，以及申请人的数量和多样性。

PROJECT SUMMARY The mission of the Deep South Center to Reduce Disparities in Chronic Diseases is to promote health equity and reduce the burden of cardiometabolic diseases across the “Deep South” region of the United States that includes Alabama, Mississippi, and Louisiana. A key component of fulfilling this mission is growing and diversifying the workforce with the expertise necessary to conduct research related to dissemination and implementation, comparative effectiveness, and translation of evidence-based interventions for real-world settings. The primary objective of the Investigator Development Core is to prepare and mentor investigators to develop innovative research that applies a precision public health approach—best viewed as “providing the right intervention to the right population at the right time”—by paying careful attention to contextual factors at multiple levels (individual, interpersonal, organizational community, societal). To this end, we have assembled a trans-disciplinary team of investigators with expertise in translational research from across four academic partners institutions (the University of Alabama at Birmingham, Pennington Biomedical Research Center, the University of Mississippi Medical Center and Tuskegee University) as well as community stakeholders committed to addressing disparities in cardiometabolic diseases in the region. The Directors of the Investigator Development Core, together with the Center’s co-Directors and other Core Faculty, have created a robust plan for providing early-stage investigators unique training in translational research methods and access to core resources dedicated to topics essential for this work. The Investigator Development Core will establish a competitive pilot studies program that will fund a minimum of six high quality research projects annually, and will provide grant trainees a mentoring team that will offer strategies and assistance to advance the pilot studies to competitive grant applications. The Investigator Development Core will also provide access to sub- units that will provide pilot awardees, as well as the three Center projects, expertise in translational design and methodology, community participatory research, implementation and dissemination science, cost effectiveness and assessment of social determinants of health. Ultimately, these activities will yield 30 to 40 early-career investigators, allow for collaborative and focused cardiometabolic research across Academic/Research Institutions within the Deep South, and ensure engagement of local/regional community settings. Key outcomes for this core include publications and extramural grants resulting from the pilot awards, career trajectories of awardees, and numbers and diversity of applicants.