Community Engagement

项目摘要-社区参与 拟议的生命科学定量元素测绘资源具有以下潜力 通过技术、方法和软件的发展对生物医学研究产生非凡的影响 这将极大地提高研究人员解决生物学和临床中重大问题的能力 关于人类健康和疾病的研究。因此，资源的采用和传播 技术对资源领导力和技术团队极其重要。 我们实现增强协作和提供访问资源功能的目标的方法 是建立在合作与服务(C&S)项目的征集、评估和选择的基础上的。八 预期的协作和服务项目，涵盖一系列生物学和人类疾病，模型 生物体和病原体已经被识别出来。这份名单是一个更大的 研究社区包括2,300个由美国国立卫生研究院资助的专注于特定金属的活跃研究项目。 该资源将建立一个知情的、有能力的用户基础，准备采用新的方法和 技术。我们将使用访问学者计划、分析成像研讨会、会议演示 和一年一度的“生命的无机签名”研讨会，以教育和培训用户，并促进采用新的 技术。具有丰富技术培训经验的资源技术人员将为调查人员提供 以及在仪器使用、数据采集和解释方面接受直接动手培训的学生 整个资源技术系列。我们将与专业协会合作，提供一个关于新技术的短期课程 元素探测和定位技术。 我们的技术传播战略将包括提供在线访问资源软件和 可下载的标准操作规程，用于样品准备和工作流程，以及仪器定制和规范 发展。重要的是，我们将通过开发一个 资源门户。访问成熟的资源技术将利用强大的机制供外部使用 为西北大学的核心设施和用户访问协议的使用提供了适当的工具和专业知识 ANL校园。位于西北校区和ANL校区的双项目负责人将确保协调 以及跨资源的CE活动的集成。此外，我们将致力于将 适当的技术，例如正在开发的光声显微镜方法。 我们将通过跟踪评估这些传播活动对采用新技术的影响。 使用这些技术的出版物和/或P41奖被引用。我们亦会检讨 每年一次的文献，以确定这些技术如何打开了新的研究领域并刺激了新的 创新。

PROJECT SUMMARY – COMMUNITY ENGAGEMENT The proposed Resource for Quantitative Elemental Mapping for the Life Sciences has the potential for extraordinary impact on biomedical research through the development of technologies, methods, and software that will dramatically improve the ability of researchers to address significant questions in biology and clinical research concerning human health and disease. Consequently, the adoption and dissemination of Resource technologies is extremely important to the Resource leadership and technology teams. Our approach to achieving the goals of enhancing collaboration and providing access to Resource capabilities is built upon the solicitation, evaluation and selection of Collaboration and Service (C&S) projects. Eight prospective Collaboration and Service projects, which cover a range of biology and disease in humans, model organisms, and pathogens, have already been identified. This list is a modest snapshot of a much larger research community encompassing >2,300 active NIH-funded research programs focused on specific metals. The Resource will develop an informed, competent user base that is prepared to adopt the new methods and technologies. We will use a Visiting Scholar program, analytical imaging workshops, conference presentations and annual “Inorganic Signatures of Life” symposia, to educate and train users and promote adoption of new technologies. Resource technical staff, with extensive experience in technical training will provide investigators and students with direct hands-on training in instrument usage, data acquisition, and interpretation across the entire range of Resource technologies. We will partner with professional societies to offer a short course on new technologies for elemental detection and localization. Our strategies for technology dissemination will include providing online access to Resource software and downloadable SOPs for sample preparation and workflows and specifications for instrument customization and development. Importantly, we will provide robust web presence for the Resource through the development of a Resource Portal. Access to mature Resource technologies will leverage robust mechanisms for external usage of instrumentation and expertise in place for core facility usage at Northwestern and user access protocols on the ANL campus. Dual project leads located on the Northwestern and ANL campuses will ensure coordination and integration of CE activities across the Resource. In addition, we will pursue commercialization of technologies, where appropriate, such as the photoacoustic microscopy methods under development. We will assess the impact of these dissemination activities on the adoption of the new technologies by tracking publications in which these technologies are used and/or the P41 grant award is cited. We will also review the literature annually to determine how these technologies have opened new areas of inquiry and stimulated new innovations.