Community Engagement

项目概要-社区参与 拟议的生命科学定量元素绘图资源有可能 通过技术、方法和软件的发展对生物医学研究产生非凡的影响 这将极大地提高研究人员解决生物学和临床领域重大问题的能力， 研究人类健康和疾病。因此，资源的采用和传播 技术对于资源领导层和技术团队极其重要。 我们实现增强协作和提供资源访问能力目标的方法 是建立在征求，评估和选择的协作和服务（C&S）项目。八 未来的合作和服务项目，涵盖了一系列生物学和人类疾病，模型 微生物和病原体已经被确认。这份名单是一个更大的一个适度的快照 研究社区包括超过2，300个NIH资助的研究项目，专注于特定金属。 “资源”将建立一个知情、称职的用户基础，准备采用新方法， 技术.我们将使用访问学者计划，分析成像研讨会，会议演示 和年度“生命的无机特征”专题讨论会，教育和培训用户，并促进采用新的 技术.具有丰富技术培训经验的资源技术人员将为研究者提供 和学生在仪器使用，数据采集和解释的直接实践培训， 全系列的资源技术。我们将与专业协会合作，提供一个新的短期课程 元素检测和定位技术。 我们的技术传播战略将包括提供资源软件的在线访问， 可下载的样品制备SOP、工作流程和仪器定制规范， 发展重要的是，我们将通过开发一个 资源门户。获得成熟的资源技术将利用强大的外部使用机制 仪器和专业知识到位的核心设施使用在西北和用户访问协议 ANL校园位于西北和ANL校园的双项目负责人将确保协调 和跨资源的CE活动的整合。此外，我们还将继续推进 在适当的情况下，如正在开发的光声显微镜方法。 我们会评估这些推广活动对采用新科技的影响， 使用这些技术的出版物和/或引用了P41奖助金。我们亦会检讨 每年的文献，以确定这些技术如何开辟了新的调查领域，并刺激了新的 创新。

PROJECT SUMMARY – COMMUNITY ENGAGEMENT The proposed Resource for Quantitative Elemental Mapping for the Life Sciences has the potential for extraordinary impact on biomedical research through the development of technologies, methods, and software that will dramatically improve the ability of researchers to address significant questions in biology and clinical research concerning human health and disease. Consequently, the adoption and dissemination of Resource technologies is extremely important to the Resource leadership and technology teams. Our approach to achieving the goals of enhancing collaboration and providing access to Resource capabilities is built upon the solicitation, evaluation and selection of Collaboration and Service (C&S) projects. Eight prospective Collaboration and Service projects, which cover a range of biology and disease in humans, model organisms, and pathogens, have already been identified. This list is a modest snapshot of a much larger research community encompassing >2,300 active NIH-funded research programs focused on specific metals. The Resource will develop an informed, competent user base that is prepared to adopt the new methods and technologies. We will use a Visiting Scholar program, analytical imaging workshops, conference presentations and annual “Inorganic Signatures of Life” symposia, to educate and train users and promote adoption of new technologies. Resource technical staff, with extensive experience in technical training will provide investigators and students with direct hands-on training in instrument usage, data acquisition, and interpretation across the entire range of Resource technologies. We will partner with professional societies to offer a short course on new technologies for elemental detection and localization. Our strategies for technology dissemination will include providing online access to Resource software and downloadable SOPs for sample preparation and workflows and specifications for instrument customization and development. Importantly, we will provide robust web presence for the Resource through the development of a Resource Portal. Access to mature Resource technologies will leverage robust mechanisms for external usage of instrumentation and expertise in place for core facility usage at Northwestern and user access protocols on the ANL campus. Dual project leads located on the Northwestern and ANL campuses will ensure coordination and integration of CE activities across the Resource. In addition, we will pursue commercialization of technologies, where appropriate, such as the photoacoustic microscopy methods under development. We will assess the impact of these dissemination activities on the adoption of the new technologies by tracking publications in which these technologies are used and/or the P41 grant award is cited. We will also review the literature annually to determine how these technologies have opened new areas of inquiry and stimulated new innovations.