Clinical Research and Community Engagement Core

临床研究和社区参与核心

基本信息

  • 批准号:
    10504810
  • 负责人:
  • 金额:
    $ 31.26万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-03-10 至 2027-06-30
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY/ABSTRACT (Clinical Research and Community Engagement Core) The Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases (Phase 1) has successfully supported Tulane University's efforts to increase the quality and quantity of clinical and translational research in cardiometabolic diseases. The Clinical Research Core played a central role in the success of COBRE Phase 1, which included seven Research Project Leaders (RPLs) and Pilot Project Leaders (PPLs) who received one or more research grants from NIH and NSF and 310 peer-reviewed scientific articles published by COBRE investigators. This COBRE Phase 2 application aims to further develop and strengthen the clinical and translational research infrastructure at Tulane University and to continuously expand and support a critical mass of investigators with expertise in clinical and translational research in cardiometabolic diseases. In Phase 2, the Clinical Research Core will be expanded into the Clinical Research and Community Engagement (CRCE) Core and the Bioinformatics and Biostatistics Core. The CRCE Core will continue to support RPLs, PPLs, other COBRE investigators, and collaborators through our research clinics and biochemical laboratories and will expand efforts to strengthen and broaden capacity for community engagement across the translational research spectrum. The overall objectives of the CRCE Core are two-fold: to enhance and expand an effective and robust infrastructure for clinical and translational research, including research clinics, clinical and biochemical laboratories, and community engagement at Tulane University, and to facilitate and support RPLs, PPLs, other COBRE investigators, and collaborators in the planning and conduct of clinical research. To achieve these objectives, the specific aims are: 1) provide clinical research facilities and staff for study protocol development, regulatory support, participant recruitment, intervention conduct, and data collection for RPLs, PPLs, other COBRE investigators, and collaborators to implement their individual research projects, 2) provide clinical and biochemical laboratory support for the collection, processing, analysis, and storage of study specimens, 3) increase capacity for community and stakeholder engagement across the spectrum of translational research in cardiometabolic diseases to enhance study recruitment, retention, and dissemination and translation of study findings, and 4) develop a plan to ensure the long-term sustainability of Core operations. The CRCE Core is critically important for the proposed COBRE Phase 2 program. All four proposed individual Research Projects will utilize the clinical research space and staff and biochemical laboratories. In addition, community engagement support is available to RPLs, PPLs, other COBRE investigators, and collaborators. The CRCE Core will play a central role in assisting RPLs and PPLs with their Research Projects and their transition into independent investigators. The Core will also play an important role in establishing and maintaining a nationally and internationally recognized clinical and translational research program in the etiology, prevention, diagnosis, and treatment of cardiometabolic diseases at Tulane University.
项目总结/摘要(临床研究和社区参与核心) 杜兰COBRE心脏代谢疾病临床和转化研究(第1期) 成功地支持杜兰大学的努力,以提高临床和 心脏代谢疾病的转化研究。临床研究核心在 COBRE第一阶段的成功,其中包括七个研究项目负责人(RPL)和试点项目 领导者(PPL)谁收到了一个或多个研究赠款从NIH和NSF和310同行评审 COBRE研究人员发表的科学文章。COBRE第二阶段应用旨在进一步开发 加强杜兰大学的临床和转化研究基础设施,并不断 扩大和支持具有临床和转化研究专业知识的研究人员的临界质量, 心脏代谢疾病在第2阶段,临床研究核心将扩展为临床研究 和社区参与(CRCE)核心和生物信息学和生物统计学核心。CRCE核心将 通过我们的研究诊所,继续支持RPL、PPL、其他COBRE研究者和合作者 和生物化学实验室,并将扩大努力,加强和扩大社区的能力, 跨翻译研究领域的参与。CRCE核心的总体目标有两个方面: 加强和扩大临床和转化研究的有效和强大的基础设施,包括 研究诊所,临床和生化实验室,以及杜兰大学的社区参与,并 在计划和实施过程中,促进和支持RPL、PPL、其他COBRE调查人员和合作者 临床研究。为实现这些目标,具体目标是:1)提供临床研究设施, 研究方案制定、监管支持、参与者招募、干预实施和数据的工作人员 为RPL、PPL、其他COBRE研究者和合作者收集数据,以实施他们的个人研究 项目,2)提供临床和生化实验室支持的收集,处理,分析, 研究样本的储存,3)提高社区和利益相关者参与整个 心脏代谢疾病转化研究的范围,以提高研究招募,保留, 传播和翻译研究结果,以及4)制定一项计划,以确保长期可持续性 核心业务。CRCE核心对于拟议的COBRE第2阶段计划至关重要。所有四 拟议的个别研究项目将利用临床研究空间和人员以及生物化学 laboratories.此外,还向RPL、PPL、其他COBRE提供社区参与支持 研究者和合作者。CRCE核心将在协助RPL和PPL完成其 研究项目及其向独立调查员的过渡。核心也将发挥重要作用 在建立和维护一个国家和国际公认的临床和转化研究 杜兰大学心脏代谢疾病的病因学、预防、诊断和治疗项目。

项目成果

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JING CHEN其他文献

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{{ truncateString('JING CHEN', 18)}}的其他基金

Establishing A New Diagnostic Paradigm for Peripheral Artery Disease among Patients with Chronic Kidney Disease
建立慢性肾病患者周围动脉疾病的新诊断范式
  • 批准号:
    10465042
  • 财政年份:
    2021
  • 资助金额:
    $ 31.26万
  • 项目类别:
Establishing A New Diagnostic Paradigm for Peripheral Artery Disease among Patients with Chronic Kidney Disease
建立慢性肾病患者周围动脉疾病的新诊断范式
  • 批准号:
    10677577
  • 财政年份:
    2021
  • 资助金额:
    $ 31.26万
  • 项目类别:
Establishing A New Diagnostic Paradigm for Peripheral Artery Disease among Patients with Chronic Kidney Disease
建立慢性肾病患者周围动脉疾病的新诊断范式
  • 批准号:
    10186101
  • 财政年份:
    2021
  • 资助金额:
    $ 31.26万
  • 项目类别:
Regulation of RPE degeneration by REV-ERBalpha
REV-ERBalpha 对 RPE 变性的调节
  • 批准号:
    10667553
  • 财政年份:
    2020
  • 资助金额:
    $ 31.26万
  • 项目类别:
Regulation of RPE degeneration by REV-ERBalpha
REV-ERBalpha 对 RPE 变性的调节
  • 批准号:
    10218186
  • 财政年份:
    2020
  • 资助金额:
    $ 31.26万
  • 项目类别:
Regulation of RPE degeneration by REV-ERBalpha
REV-ERBalpha 对 RPE 变性的调节
  • 批准号:
    10448503
  • 财政年份:
    2020
  • 资助金额:
    $ 31.26万
  • 项目类别:
Regulation of RPE degeneration by REV-ERBalpha
REV-ERBalpha 对 RPE 变性的调节
  • 批准号:
    10029720
  • 财政年份:
    2020
  • 资助金额:
    $ 31.26万
  • 项目类别:
Wnt signaling-mediated control of blood-retinal barrier
Wnt信号介导的血视网膜屏障控制
  • 批准号:
    9918370
  • 财政年份:
    2017
  • 资助金额:
    $ 31.26万
  • 项目类别:
Clinical Research and Community Engagement Core
临床研究和社区参与核心
  • 批准号:
    10664045
  • 财政年份:
    2016
  • 资助金额:
    $ 31.26万
  • 项目类别:
Urinary Angiotensinogen Excretion and Salt-Sensitivity of Blood Pressure
尿血管紧张素原排泄和血压的盐敏感性
  • 批准号:
    8697725
  • 财政年份:
    2014
  • 资助金额:
    $ 31.26万
  • 项目类别:

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