Estimating acute impacts of unconventional oil and gas development on cause-specific hospitalization via satellite-based exposure assessment

通过基于卫星的暴露评估评估非常规石油和天然气开发对特定原因住院治疗的严重影响

• 批准号: 10507465
• 负责人: Longxiang Li
• 金额: $ 10.21万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10507465
• 关键词: Acute; Air Pollutants; Award; Chronic; Columbidae; Communities; Computer software; Crude Extracts; Data; Data Analyses; Decentralization; Development; Environment; Environmental Health; Exposure to; Funding; Gases; Generations; Health; Health Status; Hospitalization; Image; Image Analysis; Imagery; Investigation; Measures; Mediating; Mediator of activation protein; Medicare; Methods; Modeling; Monitor; Natural Gas; Observational Study; Oils; Outcome; Participant; Petroleum; Phase; Procedures; Process; Production; Proxy; Records; Refuse Disposal; Research Personnel; Resolution; Risk; Rural; Sentinel; Site; Source; TimeLine; Training; Transportation; base; beneficiary; career; cohort; epidemiology study; exposure pathway; high resolution imaging; improved; novel; open source; pollutant; predictive modeling; prevent; remote sensing; rural area; skills; spatiotemporal; temporal measurement

Project summary Onshore expansion of Unconventional oil and gas development (UOGD) is considered an emerging environmental health issue due to its disproportional proliferation in rural U.S communities and the potential health impacts on 23 million nearby residents. However, two critical gaps in exposure assessment have restricted previous studies from achieving rigorous and actionable evidence regarding the acute health effects of UOGD construction stages. First, current exposure assessments were too coarse to accurately capture the short-term variability in exposure. Due to a lack of detailed construction records, investigators had to impute construction timelines for most wells based on questionable assumptions, which likely introduce misclassification. Second, none of prior large-scale observational studies has quantified exposure to specific UOGD-sourced pollutant. Investigators instead have developed various surrogates, which proxy residential exposure with functions of auxiliary factors (e.g., distance to UOGD wells). These exposure surrogates do not account for the different transports and fates of UOGD-sourced pollutants in ambient environment, thus cannot indicate specific exposure pathway(s). Furthermore, causal inference, which provide a rigorous adjustment for confounding, have not been widely used in estimating UOGD’s health effects. The objective of this proposal is to investigate the acute health effects of UOGD constructions based on improved satellite-based exposure assessment. In the K99 phase, I will take advantage of high-resolution images obtained by multiple recently launched satellites, including Sentinel-1s, Sentinel-2s, and Dove satellites to automatically detect the daily construction stage of UOGD wells (Aim 1). Multiple state-of-art causal inferential methods will be used to estimate the acute effects of each UOGD construction stage on the risk of cause-specific hospitalization in Medicare beneficiaries based on the new exposure assessment (Aim 2).In the R00 phase, I will develop and validate new exposure metrics based on the daily concentrations of air pollutants near UOGD wells, which are observed by Sentinel 5P (Aim3). Finally, I will explore the extent to which UOGD-related air pollutants mediate any effect of UOGD construction stages (Aim4). The expected outcomes are 1) an open-source software to detect UOGD-related activities from remote sensing images; 2) exposure metrics for UOGD-related air pollutants; 3) acute causal health effects of UOGD construction. The exposure data will be made public available to advance the field.

项目摘要 非常规石油和天然气开发（UOGD）的陆上扩张被认为是新兴的 环境健康问题由于其在美国农村社区的不良扩散而导致的潜力 健康影响附近的2300万居民。但是，暴露评估中的两个关键差距 以前的研究限制了有关急性健康影响的严格和可行的证据 UOGD施工阶段。首先，当前的暴露评估太粗糙了，无法准确捕获 曝光的短期差异。由于缺乏详细的施工记录，调查人员必须算 基于可疑假设的大多数井的建筑时间表，这可能引入 错误分类。其次，先前的大规模观测研究都没有量化对特定的暴露 UOGD污染物。相反，调查人员开发了各种代理人，代理居民 辅助因子的功能（例如，到UOGD井的距离）的暴露。这些曝光代理不 在环境环境中说明UOGD污染物的不同运输和命运，因此不能 指示特定的暴露途径。此外，因果推论，为 混淆，尚未广泛用于估计UOGD的健康影响。该提议的目的是 基于改进的基于卫星的曝光，研究UOGD构造的急性健康效应 评估。在K99阶段，我将利用最近通过多个获得的高分辨率图像 推出了包括Sentinel-1，Sentinel-2s和Dove Satelites在内的卫星，以自动检测每日 UOGD Wells的建筑阶段（AIM 1）。多种最先进的因果推论方法将用于 估计每个UOGD施工阶段对特定原因住院风险的急性影响 Medicare受益人基于新的暴露评估（AIM 2）。在R00阶段，我将发展和 根据UOGD Wells附近的空气污染物的每日浓度来验证新的暴露指标 通过哨兵5p观察（AIM3）。最后，我将探索与UOGD相关的空气污染物培养基的程度 UOGD施工阶段的任何影响（AIM4）。预期的结果是1）开源软件 从遥感图像中检测与UOGD相关的活动； 2）与UOGD相关的空气的暴露指标 污染物； 3）UOGD结构的急性因果健康影响。曝光数据将公开 可用于推进该领域。