Administrative Core

行政核心 摘要 行政核心将领导、管理和支持获得性抵抗治疗的所有活动 网络(ARTnet)胰腺癌中心(ACPC)。它将在跨Artnet网络中代表ACPC 活动，以及与NCI的互动。Artnet管理核心将负责管理 ACPC项目与科学技术专长和资源在 治疗抵抗、信号转导、代谢、胰腺癌生物学、器官和小鼠模型、 免疫和非免疫基质，以及PDAC组织，用于研究癌症获得性治疗抵抗。这个 核心领导力将提供从基础到翻译的专业知识，与 ACPC的总体主题，有建立和指导大型科学团队成功的记录 以变革性的方式推进领域。我们将以创新的方式运用战略管理， 包括将新人才带入该领域的教育部分，让不同的团队参与促进新的 想法，利用与拟议目标相关的国家人才，让大学领导层参与建立支持 用于尖端科学，并利用专门的大学专业知识来促进与基础和 翻译研究计划，以培养以Artnet为中心的兴趣。行政核心将提供支持 为参与管理、协调、沟通、生物统计和生物信息学的人员提供 支持Artnet在中心和园区内的活动，其他Artnet中心，Artnet协调数据 和管理中心(CDMC)和国家癌症研究所(NCI)。行政核心还将提供 科学监督、成果传播、预算监督和与总体规划有关的文书职能 此ACPC应用程序中的研究计划。核心将实施全中心范围的活动，包括， 在ACPC项目上发展新的合作，组织年度务虚会，支持获得性癌症治疗 各个学术单位内的阻力研讨会演讲者，倡导下一代科学家 (研究生、博士后研究人员和初级教师)在ACPC成员实验室。最后， 行政核心将代表ACPC参加Artnet指导委员会。

ADMINISTRATIVE CORE Abstract The administrative core will lead, manage, and support all activities of the Acquired Resistance to Therapy Network (ARTNet) Center for Pancreatic Cancer (ACPC). It will represent ACPC at the trans-ARTNet network activities, and in interactions with NCI. The ARTNet administrative core will be responsible for managing the activities of the synergistic research ACPC projects with scientific and technical expertise and resources in the areas of therapy resistance, signaling, metabolism, pancreatic cancer biology, organoid and mouse models, immune and non-immune stroma, and PDAC tissues for studying the acquired therapy resistance in cancer. The core leadership will provide expertise spanning the basic to translational spectrum, consistent with the overarching theme of ACPC, with track records of building and guiding large scientific teams to successfully advance fields in transformative ways. We will utilize strategic management with innovative approaches, including an educational component to bring new talent into the field, engage diverse teams to facilitate new ideas, leverage national talent pertinent to the proposed goals, engage university leadership in building support for cutting-edge science, and utilize dedicated university expertise to facilitate engagement with basic and translational research programs to grow ARTNet centric interests. The administrative core will provide support for personnel involved in the administration, coordination, communication, biostatistics, and bioinformatics to support the ARTNet activities within the center and campus, other ARTNet centers, ARTNet Coordinating Data and Management Center (CDMC) and National Cancer Institutes (NCI). The administrative core will also provide scientific oversight, result dissemination, budgetary oversight, and clerical functions associated with the overall research program in this ACPC application. The core will implement center-wide activities which include, developing new collaborations on the ACPC projects, organize annual retreat, support acquired cancer therapy resistance seminar speakers within various academic units, advocate for the next generation of scientists (graduate students, postdoctoral researchers, and junior faculty) in the ACPC member laboratories. Finally, the administrative core will represent ACPC on the ARTNet steering committee.