Administrative Core
Administrative Core
批准号:
10518244
负责人:
Pankaj Kumar Singh
金额:
$11.83万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-09-20 至 2027-08-31
关键词:
Advisory CommitteesAdvocateAreaBasic ScienceBioinformaticsBiometryCancer BiologyCancer CenterCollaborationsCommunicationCommunitiesDataDevelopmentEnvironmentFacultyFosteringFunding AgencyFutureGoalsGrantHuman ResourcesImmuneInformation DisseminationInfrastructureInterventionJointsLaboratoriesLeadLeadershipLinkMalignant NeoplasmsMalignant neoplasm of pancreasMedical centerMetabolicMetabolismMonitorNational Cancer InstituteNebraskaOccupational activity of managing financesOrganoidsPilot ProjectsProgress ReportsRecordsResearchResearch PersonnelResearch Project GrantsResistanceResourcesScheduleScienceScientistSignal TransductionStromal NeoplasmStudentsTalentsTechnical ExpertiseTestingTissuesTranslational ResearchTravelUniversitiesWorkanticancer researchcancer educationcancer therapydata managementgraduate studentinnovationinterestmeetingsmembermouse modelneoplasm resourcenext generationnovelnovel therapeutic interventionoperationpreventprogramsprospectiveresistance mechanismtherapy resistanttranslational cancer researchtranslational pipelinetranslational research programtumortumor metabolismweb portal
中文摘要
行政核心
摘要
行政核心将领导、管理和支持获得性治疗抵抗的所有活动
胰腺癌网络 (ARTNet) 中心 (ACPC)。它将在跨 ARTNet 网络中代表 ACPC
活动以及与 NCI 的互动。 ARTNet 管理核心将负责管理
ACPC 项目与科学技术专业知识和资源的协同研究活动
治疗耐药性、信号传导、代谢、胰腺癌生物学、类器官和小鼠模型等领域,
免疫和非免疫基质以及 PDAC 组织,用于研究癌症的获得性治疗耐药性。的
核心领导层将提供从基础到转化领域的专业知识,与
ACPC 的总体主题,拥有建立和指导大型科学团队成功的记录
以变革性的方式推进领域。我们将以创新的方式运用战略管理,
包括将新人才带入该领域的教育部分,让多元化的团队参与进来,以促进新的
想法,利用与拟议目标相关的国家人才,让大学领导层建立支持
尖端科学,并利用专门的大学专业知识来促进基础和
转化研究项目以培养以 ARTNet 为中心的兴趣。行政核心将提供支持
参与行政、协调、沟通、生物统计和生物信息学的人员
支持中心和校园内的 ARTNet 活动、其他 ARTNet 中心、ARTNet 协调数据
管理中心 (CDMC) 和国家癌症研究所 (NCI)。行政核心还将提供
与总体相关的科学监督、结果传播、预算监督和文书职能
此 ACPC 应用程序中的研究计划。核心将实施中心范围的活动,其中包括:
在 ACPC 项目上开展新的合作,组织年度静修会,支持获得性癌症治疗
各个学术单位的抵抗研讨会发言人,倡导下一代科学家
ACPC 成员实验室的(研究生、博士后研究人员和初级教师)。最后,
行政核心将在 ARTNet 指导委员会中代表 ACPC。
英文摘要
ADMINISTRATIVE CORE
Abstract
The administrative core will lead, manage, and support all activities of the Acquired Resistance to Therapy
Network (ARTNet) Center for Pancreatic Cancer (ACPC). It will represent ACPC at the trans-ARTNet network
activities, and in interactions with NCI. The ARTNet administrative core will be responsible for managing the
activities of the synergistic research ACPC projects with scientific and technical expertise and resources in the
areas of therapy resistance, signaling, metabolism, pancreatic cancer biology, organoid and mouse models,
immune and non-immune stroma, and PDAC tissues for studying the acquired therapy resistance in cancer. The
core leadership will provide expertise spanning the basic to translational spectrum, consistent with the
overarching theme of ACPC, with track records of building and guiding large scientific teams to successfully
advance fields in transformative ways. We will utilize strategic management with innovative approaches,
including an educational component to bring new talent into the field, engage diverse teams to facilitate new
ideas, leverage national talent pertinent to the proposed goals, engage university leadership in building support
for cutting-edge science, and utilize dedicated university expertise to facilitate engagement with basic and
translational research programs to grow ARTNet centric interests. The administrative core will provide support
for personnel involved in the administration, coordination, communication, biostatistics, and bioinformatics to
support the ARTNet activities within the center and campus, other ARTNet centers, ARTNet Coordinating Data
and Management Center (CDMC) and National Cancer Institutes (NCI). The administrative core will also provide
scientific oversight, result dissemination, budgetary oversight, and clerical functions associated with the overall
research program in this ACPC application. The core will implement center-wide activities which include,
developing new collaborations on the ACPC projects, organize annual retreat, support acquired cancer therapy
resistance seminar speakers within various academic units, advocate for the next generation of scientists
(graduate students, postdoctoral researchers, and junior faculty) in the ACPC member laboratories. Finally, the
administrative core will represent ACPC on the ARTNet steering committee.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Metabolic regulation of FOLFIRINOX acquired resistance in pancreatic cancer
-
批准号:10518247
-
项目类别:
-
资助金额:$29.39万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Pancreatic Cancer ARTNet Center
-
批准号:10707504
-
项目类别:
-
资助金额:$126.6万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Cancer Metabolism Core
-
批准号:10707540
-
项目类别:
-
资助金额:$9.37万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Pancreatic Cancer ARTNet Center
-
批准号:10518243
-
项目类别:
-
资助金额:$128.43万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Cancer Metabolism Core
-
批准号:10518246
-
项目类别:
-
资助金额:$9.64万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Metabolic regulation of FOLFIRINOX acquired resistance in pancreatic cancer
-
批准号:10707541
-
项目类别:
-
资助金额:$24.65万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Administrative Core
-
批准号:10707537
-
项目类别:
-
资助金额:$30.72万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Molecular Basis of ME2-mediated Tumor Suppression in Pancreatic Cancer
-
批准号:10671029
-
项目类别:
-
资助金额:$42.2万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Mitochondrial calcium signaling in pancreatic cancer metastasis and progression
-
批准号:10363987
-
项目类别:
-
资助金额:$65.54万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Mitochondrial calcium signaling in pancreatic cancer metastasis and progression
-
批准号:10565949
-
项目类别:
-
资助金额:$62.77万
-
财政年份:2022
-
负责人:Pankaj Kumar Singh
-
依托单位:
Project 3: MUC16-Mediated Metabolic Reprograming Induces PC Metastasis
-
批准号:10203864
-
项目类别:
-
资助金额:$31.64万
-
财政年份:2018
-
负责人:Pankaj Kumar Singh
-
依托单位:
Project 3: MUC16-Mediated Metabolic Reprograming Induces PC Metastasis
-
批准号:10413940
-
项目类别:
-
资助金额:$31.01万
-
财政年份:2018
-
负责人:Pankaj Kumar Singh
-
依托单位:
Metabolic Regulation of Tumor Progression, Metastasis and Chemoresistance by SIRT5/ELK3 signaling in Pancreatic Cancer
-
批准号:10662933
-
项目类别:
-
资助金额:$0.09万
-
财政年份:2017
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting the Metabolic Basis of Cachexia in Pancreatic Cancer
-
批准号:10053712
-
项目类别:
-
资助金额:$43.41万
-
财政年份:2016
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting the Metabolic Basis of Cachexia in Pancreatic Cancer
-
批准号:10630681
-
项目类别:
-
资助金额:$2.0万
-
财政年份:2016
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting MUC1-induced Tumor-stromal Metabolic Cross-talk in Pancreatic Cancer
-
批准号:8370711
-
项目类别:
-
资助金额:$42.86万
-
财政年份:2012
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting MUC1-Mediated Tumor-Stromal Metabolic Cross-Talk in Pancreatic Cancer
-
批准号:10738314
-
项目类别:
-
资助金额:$5.48万
-
财政年份:2012
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting MUC1-Mediated Tumor-Stromal Metabolic Cross-Talk in Pancreatic Cancer
-
批准号:10630607
-
项目类别:
-
资助金额:$44.09万
-
财政年份:2012
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting MUC1-Mediated Tumor-Stromal Metabolic Cross-Talk in Pancreatic Cancer
-
批准号:10679793
-
项目类别:
-
资助金额:$5.48万
-
财政年份:2012
-
负责人:Pankaj Kumar Singh
-
依托单位:
Targeting MUC1-Mediated Tumor-Stromal Metabolic Cross-Talk in Pancreatic Cancer
-
批准号:10684833
-
项目类别:
-
资助金额:$44.09万
-
财政年份:2012
-
负责人:Pankaj Kumar Singh
-
依托单位:
海外基金