Administrative Core

行政核心

• 批准号: 10707537
• 负责人: Pankaj Kumar Singh
• 金额: $ 30.72万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707537
• 关键词: Advisory Committees; Advocate; Area; Basic Cancer Research; Basic Science; Bioinformatics; Biometry; Cancer Biology; Cancer Center; Collaborations; Communication; Communities; Data; Data Coordinating Center; Dedications; Development; Education; Environment; Faculty; Fostering; Funding Agency; Future; Goals; Grant; Human Resources; Immune; Information Dissemination; Infrastructure; Institution; Intervention; Joints; Laboratories; Lead; Leadership; Link; Malignant Neoplasms; Malignant neoplasm of pancreas; Medical center; Metabolic; Metabolism; Monitor; National Cancer Institute; Nebraska; Occupational activity of managing finances; Organoids; Pilot Projects; Postdoctoral Fellow; Progress Reports; Records; Research; Research Personnel; Research Project Grants; Resistance; Resources; Schedule; Science; Scientist; Signal Transduction; Stromal Neoplasm; Students; Talents; Technical Expertise; Testing; Tissues; Translational Research; Travel; Universities; Work; anticancer research; cancer therapy; data integration; graduate student; innovation; interest; meetings; member; mouse model; next generation; novel; novel therapeutic intervention; operation; prevent; programs; prospective; resistance mechanism; therapy resistant; translational cancer research; translational pipeline; translational research program; tumor; tumor metabolism; web portal

ADMINISTRATIVE CORE Abstract The administrative core will lead, manage, and support all activities of the Acquired Resistance to Therapy Network (ARTNet) Center for Pancreatic Cancer (ACPC). It will represent ACPC at the trans-ARTNet network activities, and in interactions with NCI. The ARTNet administrative core will be responsible for managing the activities of the synergistic research ACPC projects with scientific and technical expertise and resources in the areas of therapy resistance, signaling, metabolism, pancreatic cancer biology, organoid and mouse models, immune and non-immune stroma, and PDAC tissues for studying the acquired therapy resistance in cancer. The core leadership will provide expertise spanning the basic to translational spectrum, consistent with the overarching theme of ACPC, with track records of building and guiding large scientific teams to successfully advance fields in transformative ways. We will utilize strategic management with innovative approaches, including an educational component to bring new talent into the field, engage diverse teams to facilitate new ideas, leverage national talent pertinent to the proposed goals, engage university leadership in building support for cutting-edge science, and utilize dedicated university expertise to facilitate engagement with basic and translational research programs to grow ARTNet centric interests. The administrative core will provide support for personnel involved in the administration, coordination, communication, biostatistics, and bioinformatics to support the ARTNet activities within the center and campus, other ARTNet centers, ARTNet Coordinating Data and Management Center (CDMC) and National Cancer Institutes (NCI). The administrative core will also provide scientific oversight, result dissemination, budgetary oversight, and clerical functions associated with the overall research program in this ACPC application. The core will implement center-wide activities which include, developing new collaborations on the ACPC projects, organize annual retreat, support acquired cancer therapy resistance seminar speakers within various academic units, advocate for the next generation of scientists (graduate students, postdoctoral researchers, and junior faculty) in the ACPC member laboratories. Finally, the administrative core will represent ACPC on the ARTNet steering committee.

行政核心 摘要 行政核心将领导、管理和支持获得性耐药治疗的所有活动 胰腺癌中心（ACPC）。它将在trans-ARTNet网络中代表ACPC 活动，并与NCI互动。艺术培训网的行政核心将负责管理 ACPC项目的协同研究活动，具有科学和技术专门知识和资源， 治疗抗性、信号传导、代谢、胰腺癌生物学、类器官和小鼠模型领域， 免疫和非免疫基质，以及PDAC组织，用于研究癌症中的获得性治疗抗性。的 核心领导层将提供从基础到翻译的专业知识， ACPC的首要主题，具有建立和指导大型科学团队成功 以变革的方式推进领域。我们将以创新的方式利用战略管理， 包括教育部分，将新的人才引入该领域，让不同的团队参与进来， 想法，利用与拟议目标相关的国家人才，让大学领导层参与建设支持 尖端科学，并利用专门的大学专业知识，以促进与基础和 转化研究计划，以发展以ARTNet为中心的兴趣。行政核心将提供支持 对于参与管理、协调、沟通、生物统计学和生物信息学的人员， 支持中心和校园内的ARTNet活动，其他ARTNet中心，ARTNet协调数据 和管理中心（CDMC）和国家癌症研究所（NCI）。行政核心还将提供 科学监督，结果传播，预算监督和与整体相关的文书职能 在这个ACPC应用程序的研究计划。该核心将实施全中心范围的活动，其中包括， 在ACPC项目上开展新的合作，组织年度务虚会，支持获得性癌症治疗 在各个学术单位的阻力研讨会发言人，倡导下一代科学家 （研究生，博士后研究人员和初级教师）在ACPC成员实验室。最后 行政核心将在ARTNet指导委员会中代表ACPC。