HoloSurge:Multimodal 3D Holographic tool and real-time Guidance System with point-of-care diagnostics for surgical planning and interventions on liver and pancreatic cancers

HoloSurge：多模态 3D 全息工具和实时引导系统，具有护理点诊断功能，可用于肝癌和胰腺癌的手术规划和干预

• 批准号: 10109943
• 金额: $ 20.41万
• 依托单位: LEEDS TEACHING HOSPITALS NHS TRUST
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10109943
• 关键词: HoloSurge; Multimodal; 3D; Holographic; tool

Perioperative care is an intricate processthat encompasses 1) preoperative evaluation,surgical planning and preparation; 2) intraoperative procedure; and 3) postoperative management. Perioperative care depends on clinical decision-making, a continuous process that involves many healthcare professionals (incl. radiologists, surgeons, anaesthesiologists, nurses, and others) who – based on the best available evidence, clinical experience, and the patient's individual circumstances – make informed decisions on the best course of action. Even though advancementsin medical imaging modalities(CT, MRI, ultrasound) have greatly improved surgical outcomes, their interpretation towards deciding a specific course of action remains subjective. In addition, these modalities have several limitations when used alone (e.g., missed lesions; cannot provide a 3D visualization of key structures such as vessels), ultimately failing to provide a full picture of the patient’s anatomy that is shared and unambiguously understood by all in the assigned team. Due to these limitations, there are often suboptimal decisions that add to a cumulative risk of surgical complications in perioperative care. HoloSurge is a joint undertaking that brings European scientists and clinicians from high-tech companies, clinical centres, and research institutions in a consortium to deploy an innovative AI-based medical system that: i) enables automatic fusion and segmentation of state-of-the-art imaging modalities for interactive 3D holographic visualization of patients’ organs; ii) provides real-time surgical navigation; and iii) allows real-time cell-level cancer diagnostics. The solution will provide surgical teams with an unmatched holistic view of the patient’s anatomy and pathology in real-time at point of care, before and during surgery. This innovation will be validated for cancer interventions, while creating a trail of better-informed perioperative decision-making that can save countless lives.

围手术期护理是一个复杂的过程，包括1）术前评估，手术计划和准备； 2）术中程序； 3）术后管理。围手术期的护理取决于临床决策，这是一个连续的过程，涉及许多医疗保健专业人员（包括放射科医生，外科医生，麻醉师，护士等），他们基于最佳的可用证据，临床经验和患者的个人情况 - 在最佳的行动方面做出了明智的决定。尽管医学成像方式的进步（CT，MRI，超声波）大大改善了手术结果，但他们对决定特定行动方案的解释仍然是主观的。此外，这些模式在单独使用时有几个局限性（例如，遗漏的病变；无法提供诸如血管等关键结构的3D可视化），最终未能全面了解患者的解剖结构，这些解剖结构在分配团队中的所有人共享和明确理解。由于这些局限性，通常会有次优的决定增加了周期性护理中手术并发症的累积风险。 Holosurge是一项联合承诺，它将高科技公司，临床中心和研究机构的欧洲科学家和临床医生置于一个财团中，以部署基于AI的创新医学系统：i）i）可以自动融合和对交互式3D Holog thogrics of患者Organs Organs Organs Organs的交互式3D Holog thogrics sublication的最新图像形式进行自动融合和细分。 ii）提供实时手术导航； iii）允许实时细胞级癌症诊断。该解决方案将为手术团队提供无与伦比的整体视野，以实时，在手术前和手术期间实时的病理学。这项创新将得到癌症干预的验证，同时创造了一系列更有信息的定期决策，可以挽救无数生命。