Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use Disorder
应急管理和 CBT 联合治疗酒精使用障碍的有效性和结果
基本信息
- 批准号:10529075
- 负责人:
- 金额:$ 12.58万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-06-01 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AbstinenceAddressAfghanistanAftercareAlcoholsBehavior TherapyBehavioralCaringCessation of lifeClinicCocaineCognitive TherapyDataDiseaseDrug usageFDA approvedGoalsHealth TechnologyHeavy DrinkingIncentivesIndividualIntegrated Health Care SystemsInterventionIraqMeasuresMedicalMethamphetamineMonitorMorbidity - disease rateOutcomeOutpatientsPatient Self-ReportPatientsPersonsPublic HealthQuality-Adjusted Life YearsRandomizedRecording of previous eventsRewardsSecureSubstance Use DisorderSubstance abuse problemUnited StatesVeteransVeterans Health Administrationalcohol abstinencealcohol abuse therapyalcohol misusealcohol monitoringalcohol use disordercomparative cost effectivenesscomparative effectiveness trialcontingency managementcost effective treatmentcost effectivenesscost estimatecost-effectiveness evaluationcost-effectiveness ratiodesigndiagnostic criteriadrug abstinenceeffectiveness evaluationeffectiveness outcomeeffectiveness testingencryptionevidence basefollow-uphigh risk drinkingimplementation barriersimprovedincremental cost-effectivenessinnovationmHealthmedical specialtiesmortalitymultidrug abusepreventrecruitsmartphone Applicationstandard carestimulant use disordersubstance misusevoucher
项目摘要
Alcohol contributes to 88,000 deaths and costs an estimated $223 billion annually in the United States. Alcohol
use disorder (AUD) is highly prevalent in veterans; an estimated 32% of veterans meet diagnostic criteria for AUD.
The positive public health impact of reducing heavy drinking among veterans with AUD would prevent significant
medical morbidity and mortality. Behavioral incentives could increase treatment retention and increase abstinence
among Veterans with AUD. Contingency management (CM) is an intensive behavioral therapy that provides
incentives to individuals misusing substances. CM has demonstrated effect sizes beyond that of other behavioral
treatments across multiple drugs of abuse, including a trial in Veterans with AUD, which demonstrated that CM
both increased treatment retention and completion rates and was associated with increased abstinenence from
alcohol compared to standard treatment. To date, however, implementation of CM interventions has largely
focused on stimulant use disorders (e.g., cocaine; methamphetamine) due to the diffculty of monitoring abstinence
from alcohol, which requires daily monitoring. Thus, despite demonstrated efficacy, CM aproaches for treatment of
AUD are not currently available to people with AUD. Our group has developed a mobile smart-phone application
that allows patients to video themselves using a small FDA-approved alcohol breath monitor and transmits the
encrypted data to a secure server. This innovation has made the use of CM for outpatient AUD treatment feasible.
Targeting AUD with mobile CM (mCM) paired with evidenced-based cognitive behavioral therapy (CBT) will
significantly improve long-term abstinence rates and reduction in heavy drinking days among Veterans with AUD.
The aim of the current study is to evaluate the effectiveness and cost effectiveness of contingency management
as an adjunct to cognitive behavioral therapy for alcohol use disorders. The trial will also explore the potential utilty
of a long-term abstinence incentive on treatment utilization and alcohol outcomes. Proposed is a comparative
effectiveness trial with a 2 x 2 factorial design in which 160 Veterans with AUD will be proactively recruited and
randomized to receive either CM as an adjunct to state-of-the-art evidenced-based CBT or CBT alone; and to one
of two long-term incentive conditions (i.e., receipt of a monetery incentive for abstinence/low-risk drinking at 6-
months vs. no incentive). This project aims to advance AUD treatment by 1) testing the effectiveness of a mobile
health approach that makes CM for AUD feasible, and 2) providing highly needed cost-effectiveness data on the
use of behavioral incentives as an adjunct to CBT for the treatment of AUD. These aims are designed to address
two significant barriers to the implementation of efficacious CM for AUD.
在美国,酒精每年导致88,000人死亡,并造成2230亿美元的损失。酒精
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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PATRICK S. CALHOUN其他文献
PATRICK S. CALHOUN的其他文献
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{{ truncateString('PATRICK S. CALHOUN', 18)}}的其他基金
Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder
联合应急管理和认知行为疗法治疗酒精使用障碍的成本效益
- 批准号:
10294373 - 财政年份:2019
- 资助金额:
$ 12.58万 - 项目类别:
Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use Disorder
应急管理和 CBT 联合治疗酒精使用障碍的有效性和结果
- 批准号:
10838706 - 财政年份:2019
- 资助金额:
$ 12.58万 - 项目类别:
Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use Disorder
应急管理和 CBT 联合治疗酒精使用障碍的有效性和结果
- 批准号:
10406962 - 财政年份:2019
- 资助金额:
$ 12.58万 - 项目类别:
Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use Disorder
应急管理和 CBT 联合治疗酒精使用障碍的有效性和结果
- 批准号:
10172808 - 财政年份:2019
- 资助金额:
$ 12.58万 - 项目类别:
Effectiveness and Outcomes of Combined Contingency Management and CBT for Alcohol Use Disorder
应急管理和 CBT 联合治疗酒精使用障碍的有效性和结果
- 批准号:
10621330 - 财政年份:2019
- 资助金额:
$ 12.58万 - 项目类别:
Mobile contingency management for smoking cessation in returning US Veterans
回国退伍军人戒烟的移动应急管理
- 批准号:
9437906 - 财政年份:2015
- 资助金额:
$ 12.58万 - 项目类别:
Mobile contingency management for smoking cessation in returning US Veterans
回国退伍军人戒烟的移动应急管理
- 批准号:
9208126 - 财政年份:2015
- 资助金额:
$ 12.58万 - 项目类别:
Abstinence Reinforcement Therapy (ART) for Rural Veteran Smokers
农村老烟民的戒断强化治疗 (ART)
- 批准号:
8485369 - 财政年份:2013
- 资助金额:
$ 12.58万 - 项目类别:
Supplemental Nicotine Administration for Smoking Cessation in PTSD
补充尼古丁治疗创伤后应激障碍 (PTSD) 患者戒烟
- 批准号:
7587732 - 财政年份:2009
- 资助金额:
$ 12.58万 - 项目类别:
Supplemental Nicotine Administration for Smoking Cessation in PTSD
补充尼古丁治疗创伤后应激障碍 (PTSD) 患者戒烟
- 批准号:
7835787 - 财政年份:2009
- 资助金额:
$ 12.58万 - 项目类别:
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