Enhancing Animal Welfare and Reproducibility of Biomedical Research at FAU

加强 FAU 的动物福利和生物医学研究的可重复性

• 批准号: 10533587
• 负责人: SYLVIA GOGRAFE
• 金额: $ 38.74万
• 依托单位: FLORIDA ATLANTIC UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2024-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10533587
• 关键词: Advisory Committees; Air; Animal Model; Animal Welfare; Animals; Biomedical Research; Caring; Core Facility; Cost Savings; Data; Devices; Dust; Effectiveness; Ensure; Environment; Equipment; Evaluation; Florida; Goals; Growth; Health; Home; House mice; Housing; Human; Immunocompromised Host; Individual; Information Systems; Infrastructure; Jupiter; Locomotion; Manuals; Medicine; Modernization; Monitor; Mouse Strains; Mus; Personal Satisfaction; Policies; Records; Reproducibility; Request for Proposals; Research; Research Activity; Research Design; Rodent; Running; Sampling; Science; Sentinel; Services; Side; Speed; Strategic Planning; Stress; Structure; System; Testing; Time; Training; Transgenic Organisms; Travel; Universities; Update; Use Effectiveness; Water Supply; animal care; animal facility; base; behavioral study; care systems; comparative; computerized; digital; disorder prevention; effectiveness evaluation; exhaust; experimental study; food surveillance; human error; humane endpoint; improved; mid-career faculty; neurobehavioral; operation; pathogen; programs; standardized care; welfare

Florida Atlantic University's (FAU's) growing research enterprise, in particular in the biomedical science, has put significant strain and demands on expanding and improving our animal care operations. As part of this growth, FAU has implemented central research core oversight, which includes the veterinary care unit, Comparative Medicine. Current operations include a policy, rate structure and advisory committee oversight. A new vivarium is slated to come online in 2022. What is currently missing in this growing-demand environment is the support required to update and modernize equipment. Yet, such modernization is desperately needed to improve upon rigor and reproducibility of research data involving animals. We here propose the acquisition of DVCTM racks to house mice in the new vivarium under the most diligent conditions. These racks will allow the minute monitoring of animal support and welfare via digitized monitoring, without disturbing the animals themselves. This will be particularly important for mice housed in the new vivarium, as most of them are involved in neurobehavioral studies, where slight disturbances can have a significant impact on research data. The acquisition of these DVCTM racks will provide a significant boost to FAU's efforts to improve and increase its research enterprise and improve the wellbeing of our animals.

佛罗里达大西洋大学（FAU）不断发展的研究事业，特别是在生物医学方面