Protecting Healthcare Workers' Health and Well-being: The Joint Effects of Sleep and Pain, and Moderations by Work Characteristics

保护医护人员的健康和福祉：睡眠和疼痛的共同影响以及工作特征的调节

• 批准号: 10537330
• 负责人: Christina Xuong Mu
• 金额: $ 3.23万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-12-21 至 2024-12-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10537330
• 关键词: Address; Adult; Affect; Affective; Age; Aging; Attention; COVID-19 pandemic; Cessation of life; Characteristics; Chronic; Chronic Insomnia; Clinical; Clinical Trials; Cognitive; Coupled; Data; Data Set; Development; Dopamine; Elderly; Exposure to; Family health status; Feeling; Fibromyalgia; Future; General Population; Health; Health Personnel; Health Promotion; Healthcare Systems; Hour; Individual; Injury; Intervention; Joints; Knowledge; Life; Lifting; Link; Manuscripts; Medical Errors; Mental Health; Modeling; Moods; Norepinephrine; Occupations; Opioid; Outcome; Outcomes Research; Pain; Pain management; Pathway interactions; Patient Care; Patients; Personal Satisfaction; Persons; Pharmacology; Policies; Population; Productivity; Psyche structure; Publishing Peer Reviews; Race; Reporting; Research; Resources; Risk; Risk Factors; Running; Sampling; Serotonin; Site; Sleep; Sleep Deprivation; Sleeplessness; Surveys; Symptoms; Testing; Time; Training; United States; Work; Workplace; alternative treatment; associated symptom; burnout; chronic pain; cognitive function; contextual factors; daily pain; data harmonization; depressive symptoms; design; diaries; experience; foot; health disparity; improved; middle age; mortality; negative affect; pain sensitivity; pain symptom; patient safety; physical conditioning; poor sleep; protective factors; research study; sex; shift work; sleep health; sleep quality; sociodemographics; stressor; symposium; synergism; time use

PROJECT SUMMARY/ABSTRACT The relationship between sleep and pain is often described as a vicious cycle, such that poor sleep health and pain cause and exacerbate one another. There is evidence that sleep and pain share the same underlying mechanisms involving serotonin, dopamine, and norepinephrine pathways. While most research to date has focused on the individual effects of sleep or pain on health, the current study proposes to shift this paradigm to study the joint effects of poor sleep and pain among an at-risk group, healthcare workers (HCWs). HCWs are uniquely suited as the focus of this research question because apart from clinical populations (e.g., those with chronic pain or insomnia), HCWs are at greater risk of poorer sleep and pain compared to the general population. The COVID-19 pandemic has exacerbated HCWs' feelings of burden and burnout, as well as brought more attention to these timely issues of the health and well-being among HCWs. Earlier work has found that HCWs experience shorter sleep duration, poorer sleep quality, work-related pain, and the spontaneous onset of pain. There is evidence that sleep and pain have a bidirectional relationship. In Aim 1, the proposed study will examine the joint effects of poor sleep health and pain, and how this negative synergy affects physical, mental, and cognitive health and well-being. Given the ample research studying the moderating effects of work characteristics, Aim 2 will investigate whether job demands and resources moderate the relationship between the joint effects of sleep and pain on health outcomes. These aims will be examined cross-sectionally and over time using survey and micro-longitudinal data (collected daily over 8 days), respectively. In total, data from three separate datasets will be used (n=2,154 HCWs; 5,892 non-HCWs). The central hypothesis is that the joint effects of sleep and pain will be more prevalent among HCWs compared to non-HCWs, and that the joint effects will account for more variance than the single individual effects of sleep and pain. Greater pain reactivity to poor sleep will be associated with more chronic conditions, more negative affect and less positive affect, more depressive symptoms, and lower cognitive functioning. The second hypothesis is that greater job demands and fewer job resources will exacerbate the joint effects of poor sleep and pain. Findings may help inform future workplace interventions and policies to mitigate the harmful effects of poor sleep and pain among HCWs. The proposed training site and team are well equipped to provide the necessary resources to address these aims. Upon completing this project, the PI will acquire the theoretical and statistical knowledge to study the joint effects of sleep and pain among other at-risk groups like older adults. The study team will disseminate their findings by publishing peer-reviewed manuscripts, presenting at conferences, and contributing to the development of pilot interventions to mitigate the joint effects of sleep and pain for all.

项目概要/摘要 睡眠和疼痛之间的关系通常被描述为恶性循环，睡眠健康状况不佳会导致疼痛。 疼痛会互相引起并加剧。有证据表明睡眠和疼痛具有相同的基础 涉及血清素、多巴胺和去甲肾上腺素途径的机制。虽然迄今为止大多数研究都 当前的研究重点关注睡眠或疼痛对健康的个体影响，建议将这种范式转变为 研究睡眠不佳和疼痛对高危人群——医护人员 (HCW) 的联合影响。医护人员是 特别适合作为本研究问题的焦点，因为除了临床人群（例如，那些患有 慢性疼痛或失眠），与普通人群相比，医务人员睡眠质量较差和疼痛的风险更大。 COVID-19大流行加剧了医护人员的负担和倦怠感，并带来了更多 关注医护人员健康和福祉的这些及时问题。早期的研究发现，医护人员 睡眠时间较短、睡眠质量较差、工作相关疼痛以及自发性疼痛。 有证据表明睡眠和疼痛具有双向关系。在目标 1 中，拟议的研究将审查 睡眠健康状况不佳和疼痛的联合影响，以及这种负面协同作用如何影响身体、精神和健康 认知健康和福祉。鉴于有大量研究工作的调节作用 特征，目标 2 将调查工作需求和资源是否调节两者之间的关系 睡眠和疼痛对健康结果的联合影响。这些目标将得到横断面和全面的审查 分别使用调查和微观纵向数据（8 天内每天收集）的时间。总共来自三个的数据 将使用单独的数据集（n=2,154 名医护人员；5,892 名非医护人员）。中心假设是联合效应 与非医护人员相比，睡眠和疼痛在医护人员中更为普遍，并且联合效应将 比睡眠和疼痛的单个个体影响更大的差异。对穷人的疼痛反应更大 睡眠与更多的慢性疾病、更多的负面影响和更少的积极影响相关，更多 抑郁症状和认知功能较低。第二个假设是更大的工作需求和 工作资源减少将加剧睡眠质量差和疼痛的联合影响。研究结果可能有助于为未来提供信息 工作场所干预措施和政策，以减轻医护人员睡眠不佳和疼痛的有害影响。这 拟议的培训地点和团队装备精良，可以提供实现这些目标所需的资源。 完成该项目后，PI 将获得理论和统计知识来研究联合效应 老年人等其他高危人群的睡眠和疼痛问题。研究小组将通过以下方式传播他们的发现 发表同行评审的手稿，在会议上发言，并为试点的发展做出贡献 减轻睡眠和疼痛对所有人的联合影响的干预措施。