Protecting Healthcare Workers' Health and Well-being: The Joint Effects of Sleep and Pain, and Moderations by Work Characteristics

保护医护人员的健康和福祉：睡眠和疼痛的共同影响以及工作特征的调节

• 批准号: 10537330
• 负责人: Christina Xuong Mu
• 金额: $ 3.23万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-12-21 至 2024-12-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10537330
• 关键词: Address; Adult; Affect; Affective; Age; Aging; Attention; COVID-19 pandemic; Cessation of life; Characteristics; Chronic; Chronic Insomnia; Clinical; Clinical Trials; Cognitive; Coupled; Data; Data Set; Development; Dopamine; Elderly; Exposure to; Family health status; Feeling; Fibromyalgia; Future; General Population; Health; Health Personnel; Health Promotion; Healthcare Systems; Hour; Individual; Injury; Intervention; Joints; Knowledge; Life; Lifting; Link; Manuscripts; Medical Errors; Mental Health; Modeling; Moods; Norepinephrine; Occupations; Opioid; Outcome; Outcomes Research; Pain; Pain management; Pathway interactions; Patient Care; Patients; Personal Satisfaction; Persons; Pharmacology; Policies; Population; Productivity; Psyche structure; Publishing Peer Reviews; Race; Reporting; Research; Resources; Risk; Risk Factors; Running; Sampling; Serotonin; Site; Sleep; Sleep Deprivation; Sleeplessness; Surveys; Symptoms; Testing; Time; Training; United States; Work; Workplace; alternative treatment; associated symptom; burnout; chronic pain; cognitive function; contextual factors; daily pain; data harmonization; depressive symptoms; design; diaries; experience; foot; health disparity; improved; middle age; mortality; negative affect; pain sensitivity; pain symptom; patient safety; physical conditioning; poor sleep; protective factors; research study; sex; shift work; sleep health; sleep quality; sociodemographics; stressor; symposium; synergism; time use

PROJECT SUMMARY/ABSTRACT The relationship between sleep and pain is often described as a vicious cycle, such that poor sleep health and pain cause and exacerbate one another. There is evidence that sleep and pain share the same underlying mechanisms involving serotonin, dopamine, and norepinephrine pathways. While most research to date has focused on the individual effects of sleep or pain on health, the current study proposes to shift this paradigm to study the joint effects of poor sleep and pain among an at-risk group, healthcare workers (HCWs). HCWs are uniquely suited as the focus of this research question because apart from clinical populations (e.g., those with chronic pain or insomnia), HCWs are at greater risk of poorer sleep and pain compared to the general population. The COVID-19 pandemic has exacerbated HCWs' feelings of burden and burnout, as well as brought more attention to these timely issues of the health and well-being among HCWs. Earlier work has found that HCWs experience shorter sleep duration, poorer sleep quality, work-related pain, and the spontaneous onset of pain. There is evidence that sleep and pain have a bidirectional relationship. In Aim 1, the proposed study will examine the joint effects of poor sleep health and pain, and how this negative synergy affects physical, mental, and cognitive health and well-being. Given the ample research studying the moderating effects of work characteristics, Aim 2 will investigate whether job demands and resources moderate the relationship between the joint effects of sleep and pain on health outcomes. These aims will be examined cross-sectionally and over time using survey and micro-longitudinal data (collected daily over 8 days), respectively. In total, data from three separate datasets will be used (n=2,154 HCWs; 5,892 non-HCWs). The central hypothesis is that the joint effects of sleep and pain will be more prevalent among HCWs compared to non-HCWs, and that the joint effects will account for more variance than the single individual effects of sleep and pain. Greater pain reactivity to poor sleep will be associated with more chronic conditions, more negative affect and less positive affect, more depressive symptoms, and lower cognitive functioning. The second hypothesis is that greater job demands and fewer job resources will exacerbate the joint effects of poor sleep and pain. Findings may help inform future workplace interventions and policies to mitigate the harmful effects of poor sleep and pain among HCWs. The proposed training site and team are well equipped to provide the necessary resources to address these aims. Upon completing this project, the PI will acquire the theoretical and statistical knowledge to study the joint effects of sleep and pain among other at-risk groups like older adults. The study team will disseminate their findings by publishing peer-reviewed manuscripts, presenting at conferences, and contributing to the development of pilot interventions to mitigate the joint effects of sleep and pain for all.

项目摘要/摘要 睡眠和疼痛之间的关系通常被描述为恶性循环，因此睡眠不良和 疼痛原因并互相加剧。有证据表明睡眠和疼痛共享相同的基础 涉及5-羟色胺，多巴胺和去甲肾上腺素途径的机制。迄今为止大多数研究 目前的研究专注于睡眠或疼痛对健康的影响，建议将此范式转移到 研究高危人群，医护人员（HCWS）的睡眠不良和疼痛的联合影响。 HCW是 特别适合该研究问题的重点，因为除了临床人群（例如那些患有临床人群） 慢性疼痛或失眠），与普通人群相比，HCW的睡眠和疼痛较差的风险更大。 COVID-19大流行使HCWS的负担和倦怠感加剧了，并带来了更多 注意HCW中健康和福祉的这些及时问题。较早的工作发现HCWS 体验较短的睡眠时间，睡眠质量较差，与工作有关的疼痛以及疼痛的自发发作。 有证据表明睡眠和疼痛具有双向关系。在AIM 1中，拟议的研究将检查 睡眠不良和疼痛不良的联合影响，以及这种负面的协同作用如何影响身体，精神和 认知健康和福祉。鉴于研究工作的调节作用的大量研究 特征，AIM 2将调查工作需求和资源是否在 睡眠和疼痛的联合影响对健康结果。这些目标将在横截面上进行检查 使用调查和微纵向数据（分别在8天内收集）的时间。总共三个数据 将使用单独的数据集（n = 2,154 HCW； 5,892个非HCWS）。中心假设是关节效应 与非HCW相比 与睡眠和疼痛的单个单个影响相比，差异更多。对较差的疼痛反应更大 睡眠将与更多的慢性疾病，更多的负面影响和更少的积极影响有关，更多 抑郁症状，认知功能降低。第二个假设是，更高的工作需求和 更少的工作资源会加剧睡眠和疼痛不良的联合影响。调查结果可能有助于告知未来 工作场所干预和政策减轻HCW的睡眠和疼痛不良的有害影响。这 拟议的培训站点和团队都有能力提供必要的资源来解决这些目标。 完成该项目后，PI将获取理论和统计知识以研究联合效应 睡眠和疼痛等其他高风险群体，例如老年人。研究团队将通过 出版同行评审的手稿，在会议上介绍，并为飞行员的发展做出贡献 干预措施减轻所有人的睡眠和疼痛的关节作用。