The Don S. Fredrickson Lipid Research Conference

摘要 唐·S·弗雷德里克森脂质研究会议(FLRC)汇集了科学家和 受训者研究脂和脂蛋白代谢对发育和 心脏代谢疾病的治疗。FLRC是以已故的唐·S·弗雷德里克斯的名字命名的 在1966-1974年间担任国家心脏研究所(现在的NHLBI)主任，后来 NIH，开发了血脂异常(I-V型)的临床分类，描述了Tangier的 疾病，并在脂蛋白代谢方面取得了开创性的发现。最重要的是，他训练 基础和临床科学家和实践者，他们对 脂蛋白代谢领域。 自2016年以来，对外关系与合作委员会采用了轮流主办机构的模式，第一个模式是 在肯塔基大学与萨哈心血管研究中心联合举行 研究日。自那以后，对外汉语教学与合作中心一直由范德比尔特大学、加州大学 辛辛那提。2022年大会将由杜克大学和北方大学主办 北卡罗来纳州糖尿病研究日。对外汉语教学中心将在 2023年由范德比尔特大学主办，2024年由威斯康星医学院主办。 2022年弗雷德里克森会议的主旨演讲包括诺斯大学的凯伦·莫尔克 Carolina和Deborah Muoio，杜克大学，会议的第一天和第三天。科学的 会议内容包括脂代谢、脂肪组织、脂蛋白代谢、 还有血脂和身体成分。会议的第二天将由朝鲜主办 卡罗莱纳糖尿病研究中心。议程包括额外的科学会议；多个 “海报推介”环节(5-7个，受训人员90秒演讲)和两个评委海报 会话。对外关系研究中心非常重视学生和研究员、早期职业教职员工以及 代表不足的群体。综合议程为参加培训的每一位学员提供 有机会在舞台上展示他们的研究成果，与该领域的领导者建立网络，并拓宽 他们对脂代谢和心脏代谢性疾病研究的范围和理解。 我们的形式鼓励各级科学家之间的非正式互动，提供 创新的思想交流和合成方法将推动脂质领域的发展 研究进展。这次会议将产生很大的影响，因为该计划涉及基础科学 这一发现具有临床意义。因此，预计这次会议将提供新的 不仅对脂类代谢的基本方面，而且对如何治疗，并最终 治愈，各种各样的心脏代谢性疾病状态。

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier’s Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model, the first of which was held at the University of Kentucky in conjunction with the Saha Cardiovascular Research Center Research Day. The FLRC has since been hosted by Vanderbilt University, the University of Cincinnati. The 2022 conference will be hosted by Duke University and the University of North Carolina in conjunction with the North Carolina Diabetes Research Day. The FLRC will be hosted by Vanderbilt University in 2023 and the Medical College of Wisconsin in 2024. Keynote Lectures at the 2022 Fredrickson conference include Karen Mohlke, University of North Carolina and Deborah Muoio, Duke University on Days 1 and 3 of the conference. The scientific sessions include Novel Models in Lipid Metabolism, Adipose Tissue, Lipoprotein Metabolism, and Lipids and Body Composition. Day 2 of the conference will be sponsored by the North Carolina Diabetes Research Center. The agenda includes additional scientific sessions; multiple “Poster Pitch” sessions (5-7, 90-second presentations by trainees) and two judged poster sessions. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. The combined agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.