The Don S. Fredrickson Lipid Research Conference

唐·弗雷德里克森脂质研究会议

• 批准号: 10539150
• 负责人: Gregory A Graf
• 金额: $ 1.7万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10539150
• 关键词: Address; Adipose tissue; Apolipoproteins; Basic Science; Biological Models; Body Composition; Cardiometabolic Disease; Cardiovascular Diseases; Cardiovascular system; Ceramides; Classification; Clinical; Clinical Investigator; Collaborations; Development; Diabetes Mellitus; Disease Progression; Dyslipidemias; Ensure; Faculty; Fostering; Goals; Heart; Hypertension; Hypertriglyceridemia; Institutes; Institution; Insulin Resistance; Kentucky; Lipids; Lipoproteins; Metabolic Diseases; Metabolic syndrome; Metabolism; Midwestern United States; Mitochondria; Modeling; Molecular Genetics; Names; National Heart, Lung, and Blood Institute; North Carolina; Obesity; Oral; Participant; Research; Research Activity; Research Personnel; Research Project Grants; Role; Science; Scientist; Seminal; Senior Scientist; Students; Talents; Tangier Disease; Technology; Thinking; Training; Underrepresented Populations; United States National Institutes of Health; Universities; Wisconsin; cardiovascular risk factor; career; career development; clinically significant; early-career faculty; experience; innovation; insight; lectures; lipid metabolism; medical schools; meetings; new technology; novel; posters; programs; relative cost; social; social engagement; symposium; translational scientist

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier’s Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model, the first of which was held at the University of Kentucky in conjunction with the Saha Cardiovascular Research Center Research Day. The FLRC has since been hosted by Vanderbilt University, the University of Cincinnati. The 2022 conference will be hosted by Duke University and the University of North Carolina in conjunction with the North Carolina Diabetes Research Day. The FLRC will be hosted by Vanderbilt University in 2023 and the Medical College of Wisconsin in 2024. Keynote Lectures at the 2022 Fredrickson conference include Karen Mohlke, University of North Carolina and Deborah Muoio, Duke University on Days 1 and 3 of the conference. The scientific sessions include Novel Models in Lipid Metabolism, Adipose Tissue, Lipoprotein Metabolism, and Lipids and Body Composition. Day 2 of the conference will be sponsored by the North Carolina Diabetes Research Center. The agenda includes additional scientific sessions; multiple “Poster Pitch” sessions (5-7, 90-second presentations by trainees) and two judged poster sessions. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. The combined agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.

摘要 唐S。弗雷德里克森脂质研究会议（FLRC）汇集了科学家和 研究脂质和脂蛋白代谢对发育的影响， 心脏代谢疾病的治疗。FLRC是以已故的Don S.什么弗雷德里克 1966年至1974年担任国家心脏研究所（现为NHLBI）主任， NIH开发了血脂异常的临床分类（I-V型），描述了Tangier的 在脂蛋白代谢方面有重大发现。最重要的是，他训练 基础和临床科学家和从业人员，他们对 脂蛋白代谢领域。 自2016年以来，FLRC采用了轮换机构主办模式，其中第一个是 在肯塔基州大学与萨哈心血管研究中心联合举行 研究日此后，FLRC由范德比尔特大学主办， 辛辛那提。2022年的会议将由杜克大学和北方大学主办 卡罗莱纳与北卡罗来纳州糖尿病研究日。FLRC将在 2023年由范德比尔特大学主办，2024年由威斯康星州医学院主办。 2022年弗雷德里克森会议的主题演讲包括北卡罗来纳大学的Karen Mohlke 卡罗莱纳和黛博拉Muoio，杜克大学在第1天和第3天的会议。科学 会议包括脂质代谢，脂肪组织，脂蛋白代谢， 以及脂质和身体成分。会议的第二天将由北 卡罗莱纳糖尿病研究中心。议程包括额外的科学会议;多个 “海报推介”课程（5-7节，学员90秒演讲）和两张经过评审的海报 sessions. FLRC非常重视学生和研究员，早期职业教师， 代表性不足的群体。综合议程为每一位学员提供了 有机会在舞台上展示他们的研究，与该领域的领导者建立联系，并扩大 他们的研究范围和对脂质代谢和心脏代谢疾病的理解。 我们的形式鼓励各级科学家之间的非正式互动， 创新的方法来交流思想和综合，将推动脂质领域 研究向前。该会议将产生很大的影响，因为该计划涵盖基础科学 临床意义的发现。因此，预计会议将提供新的 不仅了解脂质代谢的基本方面，而且了解如何治疗，最终 治愈，各种心脏代谢疾病状态。