Don S. Fredrickson Lipid Research Conference

唐·S·弗雷德里克森脂质研究会议

• 批准号: 10752509
• 负责人: Gregory A Graf
• 金额: $ 1万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10752509
• 关键词: Address; Adipose tissue; Atherosclerosis; Award; Basic Science; Cardiometabolic Disease; Cardiovascular Diseases; Classification; Clinical; Clinical Investigator; Collaborations; Dedications; Development; Diabetes Mellitus; Doctor of Philosophy; Dyslipidemias; Ensure; Esters; Faculty; Fatty Acids; Fostering; Goals; Heart; Hypertension; Hypertriglyceridemia; Institution; Insulin Resistance; Kentucky; Lipase; Lipids; Lipoproteins; Metabolic Diseases; Metabolic syndrome; Metabolism; Midwestern United States; Mission; Modeling; Names; National Heart, Lung, and Blood Institute; North Carolina; Obesity; Oral; Participant; Regulation; Research; Research Activity; Research Personnel; Research Project Grants; Role; Rotation; Science; Scientist; Seminal; Senior Scientist; Students; Talents; Tangier Disease; Technology; Thinking; Training; Triglyceride Metabolism; Underrepresented Populations; United States National Institutes of Health; Universities; Wisconsin; cardiovascular risk factor; career; career development; clinically significant; design; early-career faculty; experience; gut microbiome; hydroxy fatty acid; innovation; insight; lectures; lipid metabolism; lipoprotein lipase; medical schools; meetings; new technology; novel strategies; posters; programs; relative cost; social; social engagement; stable isotope; symposium; translational scientist

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier's Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model and has been hosted by the University of Kentucky ('16, `17, '21), Vanderbilt University ('18, `23), the University of Cincinnati ('19), Duke University and the University of North Carolina ('22). The FLRC will be hosted by the Medical College of Wisconsin in 2024 and return to UK in 2025. Keynote Lectures at the 2023 Fredrickson conference include Barbara Kahn, Harvard University and Alan Remaley, National Heart Lung and Blood Institute. The thematic scientific sessions include: Intestinal Microbiome Control of Lipid Metabolism, Stable Isotope Studies in Lipid Metabolism, Atherosclerosis Regression and Efferocytosis, Modulators of Triglyceride Metabolism & Lipoprotein Lipase. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. In accordance with that mission, the agenda also includes additional scientific sessions dedicated for trainees, a “Poster Pitch” session (5-7, 90-second presentations), and a judged poster session. By design, the agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.

摘要 唐S。弗雷德里克森脂质研究会议（FLRC）汇集了科学家和 研究脂质和脂蛋白代谢对发育的影响， 心脏代谢疾病的治疗。FLRC是以已故的Don S.什么弗雷德里克 1966年至1974年担任国家心脏研究所（现为NHLBI）主任， NIH开发了血脂异常的临床分类（I-V型），描述了Tangier的 在脂蛋白代谢方面有重大发现。最重要的是，他训练 基础和临床科学家和从业人员，他们对 脂蛋白代谢领域。 自2016年以来，FLRC采用了轮换机构主办模式，并由 肯塔基州大学（'16，' 17，'21），范德比尔特大学（' 18，'23）， 辛辛那提（'19），杜克大学和北卡罗来纳州大学（' 22）。FLRC将在 2024年由威斯康星州医学院主办，2025年返回英国。 2023年弗雷德里克森会议的主题演讲包括哈佛大学的芭芭拉·卡恩 和艾伦·雷马利，国家心肺和血液研究所。专题科学会议 包括：脂质代谢的肠道微生物组控制，脂质中的稳定同位素研究 代谢、动脉粥样硬化消退和胞饮作用、甘油三酯调节剂 代谢与脂蛋白脂肪酶。FLRC非常重视学生和研究员， 早期职业教师和代表性不足的群体。根据这一使命， 还包括额外的科学会议专门为学员，一个“海报间距”会议（5-7， 90-第二次演讲），和一个判断海报会议。通过设计，议程提供了每一个 参加培训的学员有机会在舞台上展示他们的研究，与领导者建立联系， 该领域，并扩大他们的范围和对脂质代谢研究的理解， 心脏代谢疾病。 我们的形式鼓励各级科学家之间的非正式互动， 创新的方法来交流思想和综合，将推动脂质领域 研究向前。该会议将产生很大的影响，因为该计划涵盖基础科学 临床意义的发现。因此，预计会议将提供新的 不仅了解脂质代谢的基本方面，而且了解如何治疗，最终 治愈，各种心脏代谢疾病状态。