CDC Southeastern Center of Excellence in Vector-Borne Diseases: Gateway Program

CDC 东南媒介传播疾病卓越中心：门户计划

• 批准号: 10551427
• 负责人: Rhoel David Ramos Dinglasan
• 金额: $ 200万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10551427
• 关键词: CDC; Southeastern; Center; Excellence; Vector

This is a renewal application for the CDC Southeastern Center of Excellence in Vector-Borne Diseases: Gateway Program (SECVBD) led by the University of Florida with both well-established and burgeoning collaborations with 13 universities with strong vector biology programs across the Southeastern United States (U.S.) and Puerto Rico. This integrated academic network carries the full and integrated support of state departments of health, state and federal agricultural agencies, U.S. military programs, national and international associations, and >60 local mosquito and vector control programs. Our proposal leverages the expertise across a broad remit of basic and applied vector biology as well as epidemiological disciplines to continue to maintain the success of our program in (i) establishing an integrated community of practice in public health entomology consisting of academic institutions throughout the Southeast and local, state, and federal public health agencies, to facilitate existing and future efforts in vector-borne disease (VBD) surveillance and control and (ii) expanding an effective academic, online, and internship-based training program in basic public health entomology to augment the cohort of personnel who are trained with the requisite knowledge and skills to quickly detect and respond to VBDs across the U.S., and (iii) initiating the drive towards an evidence-based set of recommendations and a tailored template of a “surveillance-response program” to ensure that local mosquito and vector control associations can better monitor and control VBDs in the U.S. For the next iteration of the SECVBD, we take advantage of the biocomplexity of tick- and mosquito-borne diseases in the Southeastern U.S. and Puerto Rico and leverage an integrated, data-driven, applied research program designed to produce maximal output in novel interventions and training paradigms within a 5-year period to tackle the following CDC priorities: (a) Laboratory/field evaluations of emerging technologies to suppress host-seeking ticks or disrupt pathogen transmission cycles; (b) Field studies aimed at optimizing application of tick control products to provide recommendations for pest control firms and homeowners regarding how to optimize tick suppression; (c) Assessments of the potential for incorporating tick management into existing mosquito management programs; (d) Investigations on the knowledge, attitudes, & behaviors regarding tick control methodologies, (e) Evaluation of the impact of existing public education programs on TBI risk & behaviors to prevent tick bite; (f) Field evaluations of emerging technologies to suppress mosquito adults (insecticide resistance); (g) Field evaluations of mosquito management approaches based on commercially available methods and products (both entomological and human-related outcome measures); and (h) Evaluations of the effectiveness of operational control activities targeting all mosquito stages (including insecticide resistance). The goal is to maintain our established, comprehensive, applied, and basic research program to further our understanding of VBD transmission to prevent VBDs in the continental U.S. and territories.

这是CDC东南部卓越中心矢量传播疾病中心的续签申请：Gateway 计划（SECVBD）由佛罗里达大学领导 美国东南部（美国）和波多黎各拥有13所具有强大媒介生物学计划的大学 Rico。这个综合的学术网络提供了国家卫生部门的全部和综合支持， 州和联邦农业机构，美国军事计划，国家和国际协会，> 60 当地的蚊子和矢量控制程序。我们的提议利用了广泛的基本知名度的专业知识 并应用媒介生物学以及流行病学学科，以继续维持我们的成功 （i）建立公共卫生昆虫学实践综合社区的计划 整个东南，地方，州和联邦公共卫生机构的学术机构，以促进 现有的和未来的媒介疾病（VBD）监视和控制努力以及（ii）扩大有效的 基本公共卫生昆虫学基于学术，在线和实习的培训计划，以增强队列 经过必要的知识和技能培训的人员，以快速检测和回应VBD 在整个美国，（iii）启动朝着基于证据的建议集和量身定制的驱动力 “监视响应计划”的模板，以确保本地蚊子和向量控制关联可以 更好的监控和控制美国的VBD，以进行SECVBD的下一次迭代，我们利用 美国东南部和波多黎各的tick虫和蚊子传播疾病的生物复杂性 综合，数据驱动的应用研究计划旨在在新颖的干预措施中产生最大的产出 和培训范式在5年内应对以下CDC优先级：（a）实验室/现场 评估新兴技术以抑制寻求宿主的壁虱或破坏病原体传播周期； （b）旨在优化tick控制产品应用以提供害虫建议的现场研究 控制公司和房主如何优化tick抑制； （c）评估潜力 将tick管理纳入现有的蚊子管理计划中； （d）对 知识，吸引和行为有关tick控制方法，（e）评估现有的影响 关于TBI风险和行为的公共教育计划，以防止tick咬咬伤； （f）新兴的现场评估 抑制蚊子成年人的技术（杀虫剂耐药性）； （g）蚊子管理的现场评估 基于市售方法和产品的方法（昆虫学和与人有关的方法 结果措施）； （h）评估所有针对所有目标的操作控制活动的有效性 蚊子阶段（包括杀虫剂抗性）。目的是保持我们建立的，全面的， 应用和基础研究计划，以进一步了解VBD传播，以防止VBD 美国大陆和地区。