CDC Southeastern Center of Excellence in Vector-Borne Diseases: Gateway Program

这是CDC东南部媒介传播疾病卓越中心的更新申请：网关 项目（SECVBD）由佛罗里达大学领导，与成熟和新兴的合作 与美国东南部13所拥有强大病媒生物学项目的大学合作和波多 瑞可这个综合学术网络得到了国家卫生部门的全面综合支持， 州和联邦农业机构，美国军事计划，国家和国际协会，以及>60 当地蚊子和病媒控制方案。我们的建议利用了广泛的基本职权范围内的专业知识， 和应用病媒生物学以及流行病学学科继续保持我们的成功， （一）建立公共卫生昆虫学综合实践社区，包括： 整个东南部的学术机构和地方，州和联邦公共卫生机构，以促进 现有和未来在媒介传播疾病（VBD）监测和控制方面的努力;（ii）扩大有效的 基础公共卫生昆虫学的学术、在线和基于实习的培训计划，以增加队列 受过必要知识和技能培训的人员，以快速检测和应对VBDs 在美国，以及（iii）发起一项努力，以制定一套以证据为基础的建议和一项量身定制的 “监测-应对方案”模板，以确保当地蚊子和病媒控制协会能够 更好地监测和控制美国的VBD。对于SECVBD的下一次迭代，我们利用 美国东南部和波多黎各蜱媒和蚊媒疾病的生物复杂性，并利用 综合的，数据驱动的，应用研究计划，旨在产生最大的输出在新的干预措施 （a）实验室/现场 对抑制寻找宿主的蜱虫或破坏病原体传播周期的新兴技术进行评价; (b)实地研究旨在优化蜱虫控制产品的应用，为害虫防治提供建议 控制公司和房主关于如何优化蜱虫抑制;（c）评估潜在的 将蜱虫管理纳入现有的蚊子管理方案;（d）对 关于蜱虫控制方法的知识，态度和行为，（e）评估现有蜱虫控制方法的影响 关于创伤性脑损伤风险和行为的公共教育方案，以防止蜱虫叮咬;（f）对新出现的 （g）对蚊子管理的实地评价 基于商业方法和产品（昆虫学和人类相关）的方法 （h）评价针对所有人的业务控制活动的有效性 蚊子阶段（包括杀虫剂抗性）。我们的目标是保持我们既定的，全面的， 应用和基础研究计划，以进一步了解VBD传输，以防止VBD在 美国大陆和领土。

This is a renewal application for the CDC Southeastern Center of Excellence in Vector-Borne Diseases: Gateway Program (SECVBD) led by the University of Florida with both well-established and burgeoning collaborations with 13 universities with strong vector biology programs across the Southeastern United States (U.S.) and Puerto Rico. This integrated academic network carries the full and integrated support of state departments of health, state and federal agricultural agencies, U.S. military programs, national and international associations, and >60 local mosquito and vector control programs. Our proposal leverages the expertise across a broad remit of basic and applied vector biology as well as epidemiological disciplines to continue to maintain the success of our program in (i) establishing an integrated community of practice in public health entomology consisting of academic institutions throughout the Southeast and local, state, and federal public health agencies, to facilitate existing and future efforts in vector-borne disease (VBD) surveillance and control and (ii) expanding an effective academic, online, and internship-based training program in basic public health entomology to augment the cohort of personnel who are trained with the requisite knowledge and skills to quickly detect and respond to VBDs across the U.S., and (iii) initiating the drive towards an evidence-based set of recommendations and a tailored template of a “surveillance-response program” to ensure that local mosquito and vector control associations can better monitor and control VBDs in the U.S. For the next iteration of the SECVBD, we take advantage of the biocomplexity of tick- and mosquito-borne diseases in the Southeastern U.S. and Puerto Rico and leverage an integrated, data-driven, applied research program designed to produce maximal output in novel interventions and training paradigms within a 5-year period to tackle the following CDC priorities: (a) Laboratory/field evaluations of emerging technologies to suppress host-seeking ticks or disrupt pathogen transmission cycles; (b) Field studies aimed at optimizing application of tick control products to provide recommendations for pest control firms and homeowners regarding how to optimize tick suppression; (c) Assessments of the potential for incorporating tick management into existing mosquito management programs; (d) Investigations on the knowledge, attitudes, & behaviors regarding tick control methodologies, (e) Evaluation of the impact of existing public education programs on TBI risk & behaviors to prevent tick bite; (f) Field evaluations of emerging technologies to suppress mosquito adults (insecticide resistance); (g) Field evaluations of mosquito management approaches based on commercially available methods and products (both entomological and human-related outcome measures); and (h) Evaluations of the effectiveness of operational control activities targeting all mosquito stages (including insecticide resistance). The goal is to maintain our established, comprehensive, applied, and basic research program to further our understanding of VBD transmission to prevent VBDs in the continental U.S. and territories.