Global proteomics mass spectrometry data sharing infrastructure

全球蛋白质组质谱数据共享基础设施

基本信息

  • 批准号:
    10556184
  • 负责人:
  • 金额:
    $ 73.1万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-05-19 至 2028-04-30
  • 项目状态:
    未结题

项目摘要

Global proteomics mass spectrometry data sharing infrastructure - Project Summary Technological developments and the increased pace of data generation in mass spectrometry (MS) now enable systematic probing of the human proteome, thus contributing to the characterization of biomolecular mechanisms required for the development of therapeutic responses to disease. Recognizing the scientific necessity of open data to enable new discoveries and to establish the reliability of published results, the proteomics community embraced data sharing as a common practice. The authors of thousands of papers have already publicly re- leased the underlying MS data using the resources that we propose to support and extend: the MassIVE repos- itory of mass spectrometry data and the ProteomeCentral data portal for the global ProteomeXchange consor- tium of MS data repositories. In this project, we propose to develop new proteomics MS data infrastructure, standards, workflows and data indexes to substantially advance FAIR (Findable, Accessible, Interoperable and Reusable) access to proteomics MS datasets. First, we will develop new community standards for representation of dataset metadata and for the detailed description of proteomics identifications and abundances detected in available datasets, including peptides, proteins, isoforms and post-translational modifications. We will also ex- tend workflows for dataset submission, processing and indexing to enable advanced queries by each dataset’s detected proteomics identifications. Second, we will create new infrastructure for researchers to share controlled access proteomics datasets from studies of human subjects where there may exist a significant risk of the data being identifiable. Third, we will extend the ProteomeCentral data portal to support the new dataset structures, metadata and indexes allowing for the global integration of the new levels of information across all Proteo- meXchange repositories.
全球蛋白质组学质谱数据共享基础设施-项目摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Nuno Bandeira其他文献

Nuno Bandeira的其他文献

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{{ truncateString('Nuno Bandeira', 18)}}的其他基金

MassIVE.quant: a curated and scalable community resource for quantitative proteomics
MassIVE.quant:定量蛋白质组学的精选且可扩展的社区资源
  • 批准号:
    10194582
  • 财政年份:
    2019
  • 资助金额:
    $ 73.1万
  • 项目类别:
MassIVE.quant: a curated and scalable community resource for quantitative proteomics
MassIVE.quant:定量蛋白质组学的精选且可扩展的社区资源
  • 批准号:
    9764743
  • 财政年份:
    2019
  • 资助金额:
    $ 73.1万
  • 项目类别:
MassIVE.quant: a curated and scalable community resource for quantitative proteomics
MassIVE.quant:定量蛋白质组学的精选且可扩展的社区资源
  • 批准号:
    10436166
  • 财政年份:
    2019
  • 资助金额:
    $ 73.1万
  • 项目类别:
Infrastructure
基础设施
  • 批准号:
    8798314
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Technology Research and Development Project 6: Analyzing multiplexed spectra
技术研发项目6:多重光谱分析
  • 批准号:
    8798320
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Technology Research and Development Project 3: Spectral archives and spectral networks
技术研发项目3:光谱档案和光谱网络
  • 批准号:
    9303407
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Infrastructure
基础设施
  • 批准号:
    9303404
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Technology Research and Development Project 3: Spectral archives and spectral networks
技术研发项目3:光谱档案和光谱网络
  • 批准号:
    8930723
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Infrastructure
基础设施
  • 批准号:
    8930720
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:
Technology Research and Development Project 3: Spectral archives and spectral networks
技术研发项目3:光谱档案和光谱网络
  • 批准号:
    8798317
  • 财政年份:
  • 资助金额:
    $ 73.1万
  • 项目类别:

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