Multidisciplinary Approach Training in Respiratory Research
Multidisciplinary Approach Training in Respiratory Research
批准号:
10555619
负责人:
Augustine M Choi
金额:
$66.33万
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
未结题
起止时间:
2018-02-01 至 2028-06-30
中文摘要
摘要
多学科研究培训计划(MRTP)在肺部疾病提供全面的
为致力于肺生物学和生物医学研究的个人提供研究培训。我们的主要
目标是为GME的肺科医生提供结构化的、密集的研究和教学培训
奖学金和博士学位对肺病感兴趣的科学家我们的主要目标是促进发展
成功的调查职业所需的实习技能。我们认识到必须
多学科培训和医学博士之间的互动协同作用,医学博士/博士,D.O.和博士实习生我们
提供两个培训模块的广泛访问,基础或临床科学,桥接翻译连续体。为
那些追求主要是基础科学途径,关键的培训活动将指导时间在一个基本的
研究实验室,辅以参加研究会议和有针对性的教学教育。为
那些选择更多的临床重点,关键的培训活动将指导时间进行临床重点
研究项目与教学培训相结合,重点是获得临床研究设计技能,同时确保
翻译专业知识。我们意识到,当我们专注于
为参与者提供探索其研究重点的翻译相关性的机会。Drs.
Fernando Martinez和Augustine Choi担任联合项目主任,而Robert Kaner博士和石楠博士
Stout-Delgado担任副项目总监。这个组织有很长的调查记录,
指导合作,同时完善一种强有力的方法,
一系列重叠的系统,允许仔细跟踪达到预定基准的受训人员
和时间表。该计划利用了一个充满活力的指导团队与强大的培训单位组成,
杰出的多学科教师,在肺部疾病或相关学科中具有活跃的研究项目
肺部疾病。我们成功的秘诀仍然是一个简单而集中的秘诀:a)确定三名博士后学员
每年一次,并表现出对以研究为重点的职业的兴趣; B)构建一个培养和生产力的
c)确定最适合提供培训和指导的指导者和/或共同指导者;以及d)
提供一段时间的支持(最长3年),以便培训能够进展到一个点,
可以竞争入门级奖项,并作为一个独立的调查员茁壮成长。
英文摘要
Abstract
The Multidisciplinary Research Training Program (MRTP) in pulmonary disease provides comprehensive
research training for individuals committed to a career in lung biology and biomedical research. Our main
objective is to provide structured, intensive research and didactic training to pulmonary physicians at the GME
fellowship level and Ph.D. scientists with interests in lung disease. Our primary goal is to foster the development
of trainee skills needed to pursue successful investigative careers. We recognize the importance of
multidisciplinary training and the synergy of interactions among M.D., M.D./Ph.D., D.O. and Ph.D. trainees. We
provide broad access to two training modules, basic or clinical science, bridging a translational continuum. For
those pursuing a predominantly basic science pathway, the key training activity will be mentored time in a basic
research laboratory, supplemented by participation at research conferences and targeted didactic education. For
those choosing a more clinical focus, the key training activity will be mentored time conducting a clinically focused
research project coupled with didactic training focused on gaining clinical study design skills, while ensuring
translational expertise. We appreciate that this basic-translational-clinical continuum is fluid as we focus on
providing participants opportunities to explore the translational relevance of their investigative focus. Drs.
Fernando Martinez and Augustine Choi serve as co-Program Directors, while Drs. Robert Kaner and Heather
Stout-Delgado serve as Associate Program Directors. This group has a long record of investigative and
mentoring collaboration, while refining a robust approach to comprehensive assessment of trainee progress with
a series of overlapping systems that allow a careful tracking of trainees achieving pre-established benchmarks
and timetables. The program leverages a dynamic mentoring team with robust training units comprised of an
outstanding multidisciplinary faculty with active research programs in either lung disease or in disciplines relevant
to lung disease. Our recipe for success remains a simple and focused one: a) identify three post-doctoral trainees
yearly with a demonstrated interest in a research focused career; b) structure a nurturing and productive
environment; c) identify a mentor and/or co-mentor ideally suited to provide training and mentoring; and d)
provide a period of support (up to 3 years) so that training can progress to a point where the emerging investigator
can compete for an entry level award and thrive as an independent investigator.
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DOI:
10.3389/fimmu.2021.781100
发表时间:
2021
期刊:
Frontiers in immunology
影响因子:
7.3
作者:
[Suhre K, Sarwath H, Engelke R, Sohail MU, Cho SJ, Whalen W, Alvarez-Mulett S, Krumsiek J, Choi AMK, Schmidt F]
通讯作者:
Schmidt F
DOI:
10.1016/j.ajpath.2022.04.002
发表时间:
2022-07
期刊:
AMERICAN JOURNAL OF PATHOLOGY
影响因子:
6
作者:
[Price, David R., Benedetti, Elisa, Hoffman, Katherine L., Gomez-Escobar, Luis, Alvarez-Mulett, Sergio, Capili, Allyson, Sarwath, Hina, Parkhurst, Christopher N., Lafond, Elyse, Weidman, Karissa, Ravishankar, Arjun, Cheong, Jin Gyu, Batra, Richa, Buyukozkan, Mustafa, Chetnik, Kelsey, Easthausen, Imaani, Schenck, Edward J., Racanelli, Alexandra C., Reed, Hasina Outtz, Laurence, Jeffrey, Josefowicz, Steven Z., Lief, Lindsay, Choi, Mary E., Schmidt, Frank, Borczuk, Alain C., Choi, Augustine M. K., Krumsiek, Jan, Rafii, Shahin]
通讯作者:
Rafii, Shahin
DOI:
10.1136/thoraxjnl-2021-217315
发表时间:
2022-03
期刊:
Thorax
影响因子:
10
作者:
[Whalen W, Buyukozkan M, Moore B, Moon JS, Dela Cruz CS, Martinez FJ, Choi AMK, Krumsiek J, Stout-Delgado H, Cho SJ]
通讯作者:
Cho SJ
DOI:
10.1038/s41586-022-05380-y
发表时间:
2022-11
期刊:
NATURE
影响因子:
64.8
作者:
[Arifuzzaman, Mohammad, Won, Tae Hyung, Li, Ting-Ting, Yano, Hiroshi, Digumarthi, Sreehaas, Heras, Andrea F., Zhang, Wen, Parkhurst, Christopher N., Kashyap, Sanchita, Jin, Wen-Bing, Putzel, Gregory Garbes, Tsou, Amy M., Chu, Coco, Wei, Qianru, Grier, Alex, Worgall, Stefan, Guo, Chun-Jun, Schroeder, Frank C., Artis, David]
通讯作者:
Artis, David
DOI:
10.1136/bmjresp-2021-000970
发表时间:
2021-08
期刊:
BMJ open respiratory research
影响因子:
4.1
作者:
[Plataki M, Pan D, Goyal P, Hoffman K, Choi JMK, Huang H, Safford MM, Schenck EJ]
通讯作者:
Schenck EJ
共 19 条
A Phase 1b Study of Inhaled CO for the Treatment of Sepsis-Induced ARDS
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批准号:10028004
-
项目类别:
-
资助金额:$45.29万
-
财政年份:2020
-
负责人:Augustine M Choi
-
依托单位:
Multidisciplinary Approach Training in Respiratory Research
-
批准号:10348195
-
项目类别:
-
资助金额:$49.42万
-
财政年份:2018
-
负责人:Augustine M Choi
-
依托单位:
Metabolic dysfunction regulates mitophagy-dependent necroptosis in COPD
-
批准号:9566374
-
项目类别:
-
资助金额:$4.97万
-
财政年份:2017
-
负责人:Augustine M Choi
-
依托单位:
Administrative Core
-
批准号:10172308
-
项目类别:
-
资助金额:$37.98万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:10172307
-
项目类别:
-
资助金额:$265.88万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:9300997
-
项目类别:
-
资助金额:$251.68万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:8476322
-
项目类别:
-
资助金额:$234.56万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:10636890
-
项目类别:
-
资助金额:$255.39万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Mitochondrial Dysfunction and Metabolic Regulation of the Necroptosis Pathway in COPD and IPF
-
批准号:10636900
-
项目类别:
-
资助金额:$39.99万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:9113651
-
项目类别:
-
资助金额:$241.09万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers
-
批准号:8885880
-
项目类别:
-
资助金额:$239.24万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Mitochondrial Dysfunction and Metabolic Regulation of the Necroptosis Pathway in COPD and IPF
-
批准号:10172312
-
项目类别:
-
资助金额:$37.98万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Administrative Core
-
批准号:10636891
-
项目类别:
-
资助金额:$20.02万
-
财政年份:2013
-
负责人:Augustine M Choi
-
依托单位:
Carbon Monoxide: Novel Opportunities for Therapy
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批准号:8152014
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项目类别:
-
资助金额:$294.18万
-
财政年份:2011
-
负责人:Augustine M Choi
-
依托单位:
Targeted Delivery of Progenitor Cells to the Lung
-
批准号:8073286
-
项目类别:
-
资助金额:$51.27万
-
财政年份:2011
-
负责人:Augustine M Choi
-
依托单位:
Carbon Monoxide: Novel Opportunities for Therapy
-
批准号:8320231
-
项目类别:
-
资助金额:$285.01万
-
财政年份:2011
-
负责人:Augustine M Choi
-
依托单位:
Targeted Delivery of Progenitor Cells to the Lung
-
批准号:8259731
-
项目类别:
-
资助金额:$51.28万
-
财政年份:2011
-
负责人:Augustine M Choi
-
依托单位:
Cytoprotection by Carbon Monoxide In Sepsis and Lung Injury
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批准号:8225577
-
项目类别:
-
资助金额:$50.6万
-
财政年份:2011
-
负责人:Augustine M Choi
-
依托单位:
Phase II Study of Inhales Carbon Monoxide for the Treatment of Idiopathic Pulmona
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批准号:8149936
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项目类别:
-
资助金额:$190.02万
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财政年份:2010
-
负责人:Augustine M Choi
-
依托单位:
Phase II Study of Inhales Carbon Monoxide for the Treatment of Idiopathic Pulmona
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批准号:8020261
-
项目类别:
-
资助金额:$135.98万
-
财政年份:2010
-
负责人:Augustine M Choi
-
依托单位:
海外基金