Research Resource for Human Organs and Tissues
Research Resource for Human Organs and Tissues
批准号:
10555977
负责人:
Thomas J Bell
金额:
$123.81万
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
未结题
起止时间:
1989-01-09 至 2026-06-30
关键词:
Administrative SupplementAwardAwarenessBiomedical ResearchCommunicationCommunitiesCustomDataDatabasesDevelopmentDiseaseDonor SelectionElementsEnsureFundingGrantHIV/AIDSHumanHuman ResourcesImprove AccessIndustryInfrastructureMethodologyMethodsMissionModelingModificationNormal RangeOrganPaperPrincipal InvestigatorProcessProtocols documentationPublishingRare DiseasesRecoveryResearchResearch PersonnelResourcesSamplingScientistServicesShippingSiteSourceTimeTissuesTrainingUnited States National Institutes of Healthbody systemempowermenthuman diseasehuman tissueimprovedinnovationoutreachprogramsprospectivetissue resource
中文摘要
项目主任/首席调查员(华盛顿州托马斯·贝尔):
项目摘要
人体组织器官研究资源(HTORR)是国家疾病研究的一个分支
Interchange(NDRI),一个由NIH资助的非营利性组织,其使命是提供生物医学
与人体组织一起进行研究的研究社区。对人类生物标本的需求继续
与研究人员所希望的科学问题和实验方法的复杂性同步发展
去追寻。为了满足这一要求,HTORR利用了特定于项目的方法和多样化的组织网络
来源站点(TS)为调查人员提供了获得广泛的正常和疾病信息的机会
为他们的研究提供人类生物标本。HTORR的专业知识包括五个方面,以创建
可靠的研究资源,以满足这一紧急需要的调查人员。HTORR提供:1)专家客户
为调查人员提供全天候服务和支持,2)通过机会为调查人员提供面向解决方案的方法
为每个项目制定特定于项目的协议,3)获取不同范围的人类生物标本
所有机构系统,4)正在通过多个平台进行外联工作,以提高对资源的认识;以及
5)关于捐赠人体组织用于研究的行业最佳做法和标准。实施
该计划的实施将确保为高质量、有良好注解的正常人和患病人员提供不间断的服务
来自已建立的组织来源站点网络的研究人员,与
为生物医学研究社区制定和实施创新的大规模倡议。
OMB编号0925-0001/0002(批准的第03/2020版至2023年2月28日)续页格式页
英文摘要
Program Director/Principal Investigator (Bell, Thomas, J):
Project Summary
The Human Tissue and Organ Research Resource (HTORR) is a division of the National Disease Research
Interchange (NDRI), a not-for-profit NIH-funded organization whose mission is to provide the biomedical
research community with human tissues for research. The requirements for human biospecimens continue to
evolve in tandem with complexity of scientific questions and experimental methodologies that investigators desire
to pursue. To meet this requirement, HTORR utilizes a project-specific approach and a diverse network of tissue
source sites (TSS) to provide investigators with the opportunity to obtain a broad range of normal and diseased
human biospecimens for their studies. HTORR’s expertise involves a five-pronged approach to creating a
reliable research resource to meet this emergent need for investigators. HTORR provides: 1) expert customer
service and 24/7 support for investigators, 2) a solution-oriented approach for investigators via the opportunity
to develop project-specific protocols for each project, 3) access to diverse range of human biospecimens from
all body systems, 4) ongoing outreach efforts via multiple platforms to increase awareness of the resource, and
5) industry best practices and standards regarding the donation of human tissue for research. Implementation
of this plan will ensure uninterrupted service of high quality, well annotated normal and diseased human
biospecimens to investigators from an established network of tissue source sites, in concert with the
development and implementation of innovative, large scale initiatives for the biomedical research community.
OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page Continuation Format Page
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DOI:
10.1016/j.celrep.2018.02.003
发表时间:
2018-02-20
期刊:
Cell reports
影响因子:
8.8
作者:
[Sathyamurthy A, Johnson KR, Matson KJE, Dobrott CI, Li L, Ryba AR, Bergman TB, Kelly MC, Kelley MW, Levine AJ]
通讯作者:
Levine AJ
DOI:
10.1016/j.ijpharm.2022.121693
发表时间:
2022-04-25
期刊:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
影响因子:
5.8
作者:
[Vora, Deepal, Garimella, Harsha T., German, Carrie L., Banga, Ajay K.]
通讯作者:
Banga, Ajay K.
DOI:
10.1038/s41467-018-04049-3
发表时间:
2018-04-24
期刊:
Nature communications
影响因子:
16.6
作者:
[Dhandapani R, Arokiaraj CM, Taberner FJ, Pacifico P, Raja S, Nocchi L, Portulano C, Franciosa F, Maffei M, Hussain AF, de Castro Reis F, Reymond L, Perlas E, Garcovich S, Barth S, Johnsson K, Lechner SG, Heppenstall PA]
通讯作者:
Heppenstall PA
DOI:
10.1167/iovs.18-24239
发表时间:
2018-07-02
期刊:
Investigative ophthalmology & visual science
影响因子:
4.4
作者:
[Guo X, Sriram S, Tran JA, Hutcheon AEK, Zieske JD]
通讯作者:
Zieske JD
Perfusion decellularization of a human limb: A novel platform for composite tissue engineering and reconstructive surgery.
人体肢体的灌注脱细胞:复合组织工程和重建手术的新型平台。
DOI:
10.1371/journal.pone.0191497
发表时间:
2018
期刊:
PloS one
影响因子:
3.7
作者:
[Gerli MFM, Guyette JP, Evangelista-Leite D, Ghoshhajra BB, Ott HC]
通讯作者:
Ott HC
共 41 条
Tissue Procurement Center (TPC) Supporting the Somatic Mosaicism across Human Tissues (SMaHT) Network
-
批准号:10661300
-
项目类别:
-
资助金额:$300.0万
-
财政年份:2023
-
负责人:Thomas J Bell
-
依托单位:
HTORR High Priority Alzheimer's Disease and Related Dementias Human Biospecimen Resource
-
批准号:10489968
-
项目类别:
-
资助金额:$32.14万
-
财政年份:2021
-
负责人:Thomas J Bell
-
依托单位:
Research Resource for Human Organs and Tissues (U42)
-
批准号:9761605
-
项目类别:
-
资助金额:$131.83万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Research Resource for Human Organs and Tissues (U42)
-
批准号:10628539
-
项目类别:
-
资助金额:$27.03万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR Ocular Tissue Resource for Alzheimer's Disease Research
-
批准号:10284285
-
项目类别:
-
资助金额:$33.44万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Research Resource for Human Organs and Tissues (U42)
-
批准号:10004191
-
项目类别:
-
资助金额:$131.83万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Alzheimer's-focused Administrative Supplements for NIH Grants that are not focused on Alzheimer's disease.
-
批准号:10121141
-
项目类别:
-
资助金额:$35.02万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR A&R COLD STORAGE ADMINSTRATIVE SUPPLEMENT APPLICATION
-
批准号:10600579
-
项目类别:
-
资助金额:$10.19万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Research Resource for Human Organs and Tissues (U42)
-
批准号:10434059
-
项目类别:
-
资助金额:$131.83万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR/ NIAID High Priority HIV Human Biospecimen Recovery Program
-
批准号:10405146
-
项目类别:
-
资助金额:$24.26万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Research Resource for Human Organs and Tissues (U42)
-
批准号:10208991
-
项目类别:
-
资助金额:$131.83万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR/ NIMH ASD and Control Brain Recovery Project
-
批准号:10191329
-
项目类别:
-
资助金额:$29.59万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR/ NIMH ASD and Control Brain Recovery Project
-
批准号:10429174
-
项目类别:
-
资助金额:$29.88万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
Core Management
-
批准号:10555979
-
项目类别:
-
资助金额:$123.81万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR Rare Disease Diversity Supplement
-
批准号:10608762
-
项目类别:
-
资助金额:$8.69万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
HTORR/ NIAID High Priority HIV Human Biospecimen Recovery Program
-
批准号:10175273
-
项目类别:
-
资助金额:$26.49万
-
财政年份:1989
-
负责人:Thomas J Bell
-
依托单位:
海外基金