Implementation Science and Equity

项目概要/摘要：COBRE关于实施科学与公平的总体报告 缩短将研究证据转化为临床实践的时间间隔将改善健康结果 跨越多个领域，降低社会成本。然而，直到最近，临床研究一直致力于 很少注意在现实世界的临床护理中实施循证实践。此外，农村，少数民族， 而其他亚群体在医疗保健质量方面的差距甚至更大。实施科学是一种 新兴的研究领域，专门侧重于确定整合证据的最佳方法， 常规临床护理的基础上。我们关于生物医学研究第一阶段中心的提案 卓越（COBRE）的实施科学和公平寻求建立一个研究中心， 堪萨斯大学医学中心。该COBRE将开发和测试实施科学 旨在为农村、少数民族和其他得不到充分服务的人口提供公平保健的方法。 这个多学科研究中心在机构发展奖（IDEA）状态的目标是 制定可持续和可推广的办法，减少护理方面的不平等现象。行政核心 包括一个内部咨询委员会、一个外部咨询委员会、强有力的机构支持， 来自KUMC所有学校和主要中心的大量财政和实物捐助。拟议 COBRE将由三个研究核心组成，这三个核心将为建立机构提供独特的服务。 在执行科学的能力，并将指导五个有前途的初级项目领导人。我们的总体具体 目标是： 目标1。建立和维持一个组织结构，以提供科学指导和体制 支持KUMC的实施科学和公平。 目标二。提供研究方法、参与和伦理问题方面的核心基础设施， 人类受试者，以支持项目负责人和更广泛的实施研究 KUMC社区 目标3。选择和培养优秀的，多学科的，高级和早期职业教师谁将发展 实施科学方法，为得不到充分服务的群体提供高质量的护理。 拟议中的COBRE将通过创建方法来确定 不平等、诊断原因和测试解决方案。实施科学和公平COBRE领导，博士。 Kimber Richter和Christie Befort在领导，管理和指导方面有很好的记录， 实施科学，特别是与少数民族的倡导者，以实现研究的独立性。采取 总体而言，拟议中的COBRE将创建一个可持续的、以增长为导向的计划，并付诸实施 科学，将有地方，国家和国际影响。

PROJECT SUMMARY/ABSTRACT: OVERALL COBRE on Implementation Science & Equity Shrinking the time lag for translating research evidence into clinical practice would improve health outcomes across multiple domains and reduce costs to society. Until recently, however, clinical research has devoted little attention to implementing evidence-based practices in real-world clinical care. Moreover, rural, minority, and other subpopulations experience even greater gaps in health care quality. Implementation Science is an emerging field of research that specifically focuses on identifying the best approaches to integrating evidence- based practices into routine clinical care. Our proposal for a Phase I Center of Biomedical Research Excellence (COBRE) on Implementation Science and Equity seeks to establish a research center at the University of Kansas Medical Center (KUMC). This COBRE will develop and test Implementation Science approaches designed to achieve equitable care for rural, minority, and other underserved populations. The goal of this multidisciplinary research center in an Institutional Development Award (IDeA) state is to develop sustainable and generalizable approaches to reducing inequities in care. The Administrative Core includes an internal advisory committee, an external advisory committee, strong institutional support, and substantial financial and in-kind contributions from all schools and major centers across KUMC. The proposed COBRE will consist of three research cores, which will provide unique services for building institutional capacity in implementation science and will mentor five promising junior project leaders. Our overall specific aims are to: Aim 1. Create and sustain an organizational structure to provide scientific mentoring and institutional support for implementation science and equity at KUMC. Aim 2. Provide core infrastructure in methodology, engagement, and ethical issues in research with human subjects, to support implementation research conducted by Project Leaders and the broader KUMC community. Aim 3. Select and train outstanding, multi-disciplinary, senior and early-career faculty who will develop implementation science approaches for delivering high-quality care to underserved groups. The proposed COBRE will advance the field of implementation science by creating approaches to identifying inequities, diagnosing causes, and testing solutions. Implementation Science and Equity COBRE leads, Drs. Kimber Richter and Christie Befort have strong track records in leadership, administration, and mentoring in implementation science—especially with minority investigators—to achieve research independence. Taken together, the proposed COBRE will create a sustainable and growth-oriented program in implementation science that will have local, national, and international impact.