Implementation Science and Equity

项目摘要/摘要：关于实施科学和公平的总体重点 缩短将研究证据转化为临床实践的时间间隔将改善健康结果 跨多个领域，降低社会成本。然而，直到最近，临床研究一直致力于 很少注意在现实世界的临床护理中实施循证实践。此外，农村、少数民族、 而其他亚群在医疗保健质量方面的差距更大。实施科学是一种 专门专注于确定整合证据的最佳方法的新兴研究领域- 将基于实践的做法转化为常规临床护理。我们关于建立一期生物医学研究中心的建议 卓越(Cobre)关于实施科学和公平的研究寻求在 堪萨斯大学医学中心(KUMC)。Cobre将开发和测试实现科学 旨在实现对农村、少数群体和其他未得到充分服务的人口的公平照顾的方法。 这个处于机构发展奖(IDEA)状态的多学科研究中心的目标是 制定可持续和可推广的方法，以减少护理方面的不平等。行政核心 包括内部咨询委员会、外部咨询委员会、强有力的机构支持，以及 KUMC的所有学校和主要中心都提供了大量的财政和实物捐助。建议数 COBRE将由三个研究核心组成，将为机构建设提供独特的服务 在实施科学方面的能力，并将指导五个有前途的初级项目领导人。我们的总体具体情况 目标是： 目标1.创建和维持一个组织结构，以提供科学的指导和机构 支持KUMC的实施科学和公平。 目标2.为研究中的方法学、参与性和伦理问题提供核心基础设施 人类受试者，以支持项目负责人和更广泛的人进行的实施研究 KUMC社区。 目标3.选拔和培养优秀的、多学科的、资深的和职业生涯早期的教师 实施科学方法，为服务不足的群体提供高质量的护理。 拟议的COBRE将通过创造方法来确定 不平等、诊断原因和测试解决方案。实施科学和公平科布雷博士领导。 金伯·里希特和克里斯蒂·贝福特在领导、管理和指导方面有着良好的记录 实施科学--特别是与少数族裔研究人员合作--以实现研究独立。已被占用 总之，拟议的Cobre将在实施中创建一个可持续和以增长为导向的计划 将对地方、国家和国际产生影响的科学。

PROJECT SUMMARY/ABSTRACT: OVERALL COBRE on Implementation Science & Equity Shrinking the time lag for translating research evidence into clinical practice would improve health outcomes across multiple domains and reduce costs to society. Until recently, however, clinical research has devoted little attention to implementing evidence-based practices in real-world clinical care. Moreover, rural, minority, and other subpopulations experience even greater gaps in health care quality. Implementation Science is an emerging field of research that specifically focuses on identifying the best approaches to integrating evidence- based practices into routine clinical care. Our proposal for a Phase I Center of Biomedical Research Excellence (COBRE) on Implementation Science and Equity seeks to establish a research center at the University of Kansas Medical Center (KUMC). This COBRE will develop and test Implementation Science approaches designed to achieve equitable care for rural, minority, and other underserved populations. The goal of this multidisciplinary research center in an Institutional Development Award (IDeA) state is to develop sustainable and generalizable approaches to reducing inequities in care. The Administrative Core includes an internal advisory committee, an external advisory committee, strong institutional support, and substantial financial and in-kind contributions from all schools and major centers across KUMC. The proposed COBRE will consist of three research cores, which will provide unique services for building institutional capacity in implementation science and will mentor five promising junior project leaders. Our overall specific aims are to: Aim 1. Create and sustain an organizational structure to provide scientific mentoring and institutional support for implementation science and equity at KUMC. Aim 2. Provide core infrastructure in methodology, engagement, and ethical issues in research with human subjects, to support implementation research conducted by Project Leaders and the broader KUMC community. Aim 3. Select and train outstanding, multi-disciplinary, senior and early-career faculty who will develop implementation science approaches for delivering high-quality care to underserved groups. The proposed COBRE will advance the field of implementation science by creating approaches to identifying inequities, diagnosing causes, and testing solutions. Implementation Science and Equity COBRE leads, Drs. Kimber Richter and Christie Befort have strong track records in leadership, administration, and mentoring in implementation science—especially with minority investigators—to achieve research independence. Taken together, the proposed COBRE will create a sustainable and growth-oriented program in implementation science that will have local, national, and international impact.