Technology Core

项目概要-技术核心 病毒系统生物学中心（CViSB）需要生成大型多变量数据集，其中许多数据集都是由一个或多个数据集组成的。 其中需要修改现有的实验和计算方法或创建新的 方法.技术核心的主要职责是提供最先进的高吞吐量 组学和功能服务，以支持CViSB的项目。我们将利用我们丰富的专业知识 和这些技术的经验，并确保我们保持我们的地位，作为一个尖端的 实验设施，我们将确定，开发和适应新兴技术的潜力， 进一步实现CViSB的科学目标。然后，我们将把这些创新的实验方法转化为 标准化的协议和方法适合于分发和重用。完成这些 目标并支持CViSB的总体使命，我们有以下四个目标：（1）评估， 开发和改进宿主适应性多组学分析的实验方法和分析工具 免疫功能;（2）开发和改进大规模病毒成本效益高的下一代方法 测序;（3）提供尖端的测序和组学服务，以支持数据生成 CViSB的项目和调查人员的需求;（4）创建和分发开放获取标准操作 程序、协议和方法。

Project Summary - Technology Core The Center for Viral Systems Biology (CViSB) requires the generation of large, multivariate datasets, many of which necessitate modifying existing experimental and computational approaches or creating novel methods. The Technology Core’s primary responsibility is providing state-of-the-art, high throughput omics and functional services to support CViSB’s Projects. We will leverage our considerable expertise and experience with these techniques and, to ensure that we maintain our position as a cutting-edge experimental facility, we will identify, develop and adapt emerging technologies with the potential to further CViSBs scientific aims. We will then translate these innovative experimental approaches into standardized protocols and methods that are suitable for distribution and reuse. To accomplish these objectives and support the overall mission of CViSB, we have the following four aims: (1) Evaluate, develop, and improve experimental methods and analysis tools for multi-omics analysis of host adaptive immune function; (2) Develop and improve cost-effective next-generation methods for large-scale virus sequencing; (3) Provide cutting-edge sequencing and omics services to support the data generation needs of CViSB’s Projects and investigators; and (4) Create and distribute open access standard operating procedures, protocols, and methods.