Participatory Research for Suicide Prevention in Autism

自闭症自杀预防的参与性研究

基本信息

批准号：
10595667
负责人：
Anne V Kirby
金额：
$ 16.25万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-04-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10595667
关键词：
Address Adult Advisory Committees Advocate Affect Area Attitude Clinical Clinical Trials Communities Community based prevention Community of Practice Complement Complex Data Development Education Ensure Family Family member Feedback Feeling suicidal Genetic Load Goals Health Professional Hybrids Individual Intervention Intervention Community Trial Interview Knowledge Leadership Learning Licensing Life Measures Mental Health Mentored Patient-Oriented Research Career Development Award Mentors Methods Modeling Occupational Therapist Outcome Participant Persons Population Populations at Risk Preparation Prevention Prevention Research Prevention approach Prevention strategy Process Quality of life Randomized Research Research Methodology Research Personnel Risk Risk Factors Senior Scientist Structure Suggestion Suicide Suicide prevention Testing Training Translational Research Waiting Lists Work acceptability and feasibility adult with autism spectrum disorder autism community autism spectrum disorder autistic career development clinical trial implementation community based participatory research community building empowerment evidence base experience high risk implementation facilitators implementation measures individuals with autism spectrum disorder innovation intervention refinement member mortality novel pilot test population health preventive intervention protective factors reducing suicide research study skills social communication social influence sound success suicidal suicidal behavior suicidal morbidity suicidal risk suicide model suicide mortality

项目摘要

PROJECT SUMMARY/ABSTRACT This is a K23 award application for Dr. Anne Kirby, a licensed occupational therapist with expertise in autism, to independently conduct translational research studies to reduce suicide and advance quality of life for autistic people. The K23 will provide her the support necessary to acquire critical skills in four key career development areas: 1) community-based participatory research (CBPR) approaches with autistic community partners; 2) qualitative and mixed methods research approaches; 3) efficacy and implementation clinical trials of community interventions focused on suicide prevention; and 4) research leadership and management skills. To achieve her goals, Dr. Kirby has assembled an interdisciplinary mentoring team comprised of Dr. Hillary Coon (Primary Mentor), a senior scientist and recognized leader in autism research, and three Co-Mentors: Dr. Christina Nicolaidis, an accomplished CBPR researcher with autistic adults, Dr. Susan Zickmund, an expert in qualitative and mixed methods research, and Dr. Craig Bryan, a leading suicide prevention clinical trialist. Complementing these experts, Dr. Kirby also has a 4 member advisory committee to support her proposed CBPR work with autistic stakeholders and development of a suicide prevention community-based intervention. Current evidence demonstrates that autistic individuals are at elevated risk for suicidal thoughts, suicidal behaviors, and, ultimately, suicide deaths. Suicide prevention is a high priority of autistic adults, and research is needed to better understand risk factors and prevent suicide. However, few autism researchers are trained in working effectively with the autistic community. Dr. Kirby's objective is to address the gaps in current knowledge about suicide and autism, and the lack of available evidence-based suicide prevention strategies. Her research will result in preliminary data to support a clinical trial to test a novel community-based suicide prevention intervention for autism communities. She proposes the following Specific Aims: Aim 1] Qualitatively explore suicide risk and protective factors for autistic people as well as preferred aspects of evidence-based suicide prevention interventions; Aim 2] Develop a community-based intervention built upon the PC CARES (Promoting Community Conversations About Research to End Suicide) model framework to educate and empower autism community stakeholders about autistic mental health and suicide prevention; and Aim 3] Pilot test and refine the intervention content, delivery, and efficacy and implementation measures in preparation for a Hybrid Type 1(efficacy + implementation) clinical trial. A critical component of this proposal will be the use of CBPR methods throughout the proposed aims to ensure community relevance and acceptability. The proposed research is significant because it expands our understanding of suicide risk in autistic people. The proposed research is innovative because it takes a CBPR approach and will result in the first community- based suicide prevention approach developed by and for the autistic community.

项目摘要/摘要这是安妮·柯比（Anne Kirby）博士的K23奖项，该申请是一名有执照的职业治疗师，具有自闭症专业知识，独立进行翻译研究以减少自杀和提高自闭症的生活质量人们。 K23将为她提供在四个关键职业发展中获得关键技能所需的支持区域：1）基于社区的参与性研究（CBPR）与自闭症社区合作伙伴的方法； 2）定性和混合方法研究方法； 3）功效和实施临床试验社区干预措施以预防自杀为重点； 4）研究领导和管理技能。到实现她的目标，柯比博士组建了一个由希拉里·库恩（Hillary Coon）博士组成的跨学科指导团队（主要导师），自闭症研究的高级科学家和公认的领导者，三位合伙人：博士克里斯蒂娜·尼科莱迪斯（Christina Nicolaidis 定性和混合方法研究，以及领先的自杀临床试验师Craig Bryan博士。柯比（Kirby）对这些专家的补充，还有一个4个会员咨询委员会，以支持她的建议 CBPR与自闭症利益相关者合作，并开发基于社区的自杀预防干预措施。当前的证据表明，自闭症患者的自杀念头风险较高行为，最终是自杀死亡。预防自杀是自闭症成年人的优先事项，研究需要更好地理解风险因素并防止自杀。但是，很少有自闭症研究人员接受培训与自闭症社区有效合作。柯比博士的目标是解决当前的差距关于自杀和自闭症的知识，以及缺乏可用的循证自杀预防策略。她的研究将导致初步数据支持临床试验以测试一种新型的基于社区的自杀自闭症社区的预防干预。她提出以下特定目标：目标1] 定性地探索自闭症患者的自杀风险和保护因素，以及基于证据的自杀预防干预措施；目标2]开发基于社区的干预措施 PC关心（促进有关研究的社区对话以结束自杀）模型框架教育和授权自闭症社区利益相关者有关自闭症心理健康和预防自杀的知识；目标3]试点测试并完善干预内容，交付和功效和实施措施为了准备一项混合型1（功效 +实施）临床试验。该提案的关键组成部分将在整个拟议的目的中使用CBPR方法，以确保社区相关性和可接受性。拟议的研究很重要，因为它扩大了我们对自闭症患者自杀风险的理解。拟议的研究具有创新性，因为它采用了CBPR方法，并将导致第一个社区 - 自闭症社区开发的基于自杀的预防方法。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Association between functional disability type and suicide-related outcomes among U.S. adults with disabilities in the National Survey on Drug Use and Health, 2015-2019.

DOI：
10.1016/j.jpsychires.2022.07.014
发表时间：
2022-09
期刊：
JOURNAL OF PSYCHIATRIC RESEARCH
影响因子：
4.8
作者：
Marlow, Nicole M.;Xie, Zhigang;Tanner, Rebecca;Jacobs, Molly;Hogan, Michaela K.;Joiner Jr, Thomas E.;V. Kirby, Anne
通讯作者：
V. Kirby, Anne

Autistic Adolescents' and Their Parents' Visions for the Future: How Aligned are They?