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Participatory Research for Suicide Prevention in Autism

自闭症自杀预防的参与性研究

基本信息

批准号：
10595667
负责人：
Anne V Kirby
金额：
$ 16.25万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-04-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10595667
关键词：
Address Adult Advisory Committees Advocate Affect Area Attitude Clinical Clinical Trials Communities Community based prevention Community of Practice Complement Complex Data Development Education Ensure Family Family member Feedback Feeling suicidal Genetic Load Goals Health Professional Hybrids Individual Intervention Intervention Community Trial Interview Knowledge Leadership Learning Licensing Life Measures Mental Health Mentored Patient-Oriented Research Career Development Award Mentors Methods Modeling Occupational Therapist Outcome Participant Persons Population Populations at Risk Preparation Prevention Prevention Research Prevention approach Prevention strategy Process Quality of life Randomized Research Research Methodology Research Personnel Risk Risk Factors Senior Scientist Structure Suggestion Suicide Suicide prevention Testing Training Translational Research Waiting Lists Work acceptability and feasibility adult with autism spectrum disorder autism community autism spectrum disorder autistic career development clinical trial implementation community based participatory research community building empowerment evidence base experience high risk implementation facilitators implementation measures individuals with autism spectrum disorder innovation intervention refinement member mortality novel pilot test population health preventive intervention protective factors reducing suicide research study skills social communication social influence sound success suicidal suicidal behavior suicidal morbidity suicidal risk suicide model suicide mortality

项目摘要

PROJECT SUMMARY/ABSTRACT This is a K23 award application for Dr. Anne Kirby, a licensed occupational therapist with expertise in autism, to independently conduct translational research studies to reduce suicide and advance quality of life for autistic people. The K23 will provide her the support necessary to acquire critical skills in four key career development areas: 1) community-based participatory research (CBPR) approaches with autistic community partners; 2) qualitative and mixed methods research approaches; 3) efficacy and implementation clinical trials of community interventions focused on suicide prevention; and 4) research leadership and management skills. To achieve her goals, Dr. Kirby has assembled an interdisciplinary mentoring team comprised of Dr. Hillary Coon (Primary Mentor), a senior scientist and recognized leader in autism research, and three Co-Mentors: Dr. Christina Nicolaidis, an accomplished CBPR researcher with autistic adults, Dr. Susan Zickmund, an expert in qualitative and mixed methods research, and Dr. Craig Bryan, a leading suicide prevention clinical trialist. Complementing these experts, Dr. Kirby also has a 4 member advisory committee to support her proposed CBPR work with autistic stakeholders and development of a suicide prevention community-based intervention. Current evidence demonstrates that autistic individuals are at elevated risk for suicidal thoughts, suicidal behaviors, and, ultimately, suicide deaths. Suicide prevention is a high priority of autistic adults, and research is needed to better understand risk factors and prevent suicide. However, few autism researchers are trained in working effectively with the autistic community. Dr. Kirby's objective is to address the gaps in current knowledge about suicide and autism, and the lack of available evidence-based suicide prevention strategies. Her research will result in preliminary data to support a clinical trial to test a novel community-based suicide prevention intervention for autism communities. She proposes the following Specific Aims: Aim 1] Qualitatively explore suicide risk and protective factors for autistic people as well as preferred aspects of evidence-based suicide prevention interventions; Aim 2] Develop a community-based intervention built upon the PC CARES (Promoting Community Conversations About Research to End Suicide) model framework to educate and empower autism community stakeholders about autistic mental health and suicide prevention; and Aim 3] Pilot test and refine the intervention content, delivery, and efficacy and implementation measures in preparation for a Hybrid Type 1(efficacy + implementation) clinical trial. A critical component of this proposal will be the use of CBPR methods throughout the proposed aims to ensure community relevance and acceptability. The proposed research is significant because it expands our understanding of suicide risk in autistic people. The proposed research is innovative because it takes a CBPR approach and will result in the first community- based suicide prevention approach developed by and for the autistic community.

项目总结/摘要这是K23奖的申请安妮·柯比博士，一位有执照的职业治疗师，在自闭症方面有专长，独立进行转化研究，以减少自杀和提高自闭症患者的生活质量人K23将为她提供必要的支持，以获得四个关键职业发展的关键技能领域：1）与自闭症社区合作伙伴进行基于社区的参与性研究（CBPR）; 2）定性和混合方法的研究方法; 3）有效性和实施临床试验社区干预侧重于自杀预防;和4）研究领导和管理技能。到为了实现她的目标，Kirby博士组建了一个由Hillary Coon博士组成的跨学科指导团队。（初级导师），一位资深科学家和公认的领导者在自闭症研究，和三个共同导师：博士。克里斯蒂娜·尼古拉是一位成功的CBPR自闭症成年人研究员，苏珊·齐克蒙德博士是一位专家，定性和混合方法研究，以及克雷格布赖恩博士，一个领先的自杀预防临床试验。补充这些专家，柯比博士也有一个4名成员的咨询委员会，以支持她的建议。 CBPR与自闭症利益相关者合作，并制定以社区为基础的自杀预防干预措施。目前的证据表明，孤独症患者有自杀想法的风险较高，行为，最终导致自杀死亡。预防自杀是自闭症成年人的高度优先事项，研究更好地了解风险因素和预防自杀。然而，很少有自闭症研究人员受过训练，与自闭症群体有效合作的重要性Kirby博士的目标是解决当前关于自杀和自闭症的知识，以及缺乏基于证据的自杀预防策略。她的研究将产生初步数据，以支持一项临床试验，以测试一种新的社区自杀自闭症社区的预防干预。她提出了以下具体目标：目标1] 定性研究探讨了自闭症患者的自杀风险和保护因素，以及循证自杀预防干预措施;目标2]制定基于以下内容的社区干预措施： PC CARES（促进社区关于研究结束自杀的对话）模型框架，教育和授权自闭症社区利益相关者了解自闭症心理健康和自杀预防; 及目的3]先试及完善介入的内容、提供方法、成效及推行措施为混合1型（疗效+实施）临床试验做准备。这项提议的一个关键组成部分是将在整个拟议目标中使用CBPR方法，以确保社区相关性，可接受性这项拟议中的研究意义重大，因为它扩大了我们对自闭症患者自杀风险的理解。拟议的研究是创新的，因为它采取了CBPR的方法，并将导致第一个社区- 由自闭症社区开发并为自闭症社区开发的基于自杀预防的方法。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Association between functional disability type and suicide-related outcomes among U.S. adults with disabilities in the National Survey on Drug Use and Health, 2015-2019.

DOI：
10.1016/j.jpsychires.2022.07.014
发表时间：
2022-09
期刊：
JOURNAL OF PSYCHIATRIC RESEARCH
影响因子：
4.8
作者：
Marlow, Nicole M.;Xie, Zhigang;Tanner, Rebecca;Jacobs, Molly;Hogan, Michaela K.;Joiner Jr, Thomas E.;V. Kirby, Anne
通讯作者：
V. Kirby, Anne

Autistic Adolescents' and Their Parents' Visions for the Future: How Aligned are They?