Secure Communications, Analysis and Alerts for Respiratory Diagnosis (SCAARD)

呼吸系统诊断的安全通信、分析和警报 (SCAARD)

• 批准号: 104283
• 金额: $ 37.69万
• 依托单位: CAMBRIDGE RESPIRATORY INNOVATIONS LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=104283
• 关键词: Secure; Communications; Analysis; Alerts; Respiratory

"There is a substantial market opportunity for a low-cost personal medical device which can be used by a patient to help monitor and manage their respiratory condition. In the UK alone there are over 800,000 people with Chronic Obstructive Pulmonary Disease (COPD), as well as 5.4 million people with asthma. Globally WHO estimates that there are 64 million people with COPD and 335 million people with asthma. **It is widely acknowledged that many respiratory conditions are poorly managed due to the lack of an effective personal monitor which** **measures lung performance in a convenient and cost effective manner.**This results in a high level of respiratory exacerbations, sometimes resulting in permanent lung damage and often resulting in avoidable, high cost hospital admissions.Cambridge Respiratory Innovations Limited (CRiL), of Swavesey Cambridgeshire, has identified a clear unmet need from both patients and healthcare professionals for a ""connected"" personal respiratory monitor. Doctors, respiratory nurses and patients are dissatisfied with current devices, which are peak-flow meters and spirometers (both of which require forced expiratory manoeuvres and are technique dependent). **CRiL has developed the N-Tidal Respiratory Management System, based on measuring CO2 in normal tidal breathing. Driven by the N-Tidal B personal respiratory monitor, N-Tidal will ultimately facilitate correct diagnosis and monitoring of COPD, asthma and other chronic respiratory conditions.**Innovate UK is funding research which will:1. Create the main N-Tidal Patient Database, with appropriate N3/HIPAA secure communications.2. Create a secure ""handshake"" between the central N-Tidal Database and the RESPO (Replaceable Enclosed Sensor Paired Optics), which is an intelligent N-Tidal consumable, essential for measuring the TBCO2 waveform.3. Ensure the integrity of the N-Tidal data and the alerts.**The RESPO handshake is the most innovative element in this project.** It is an essential component of the N-Tidal B. The RESPO is a time-based consumable which will be prescribable and will provide the revenue streams for N-Tidal. Its use will link the patient, the device and the database, validating that the data analysis and time period has been funded. **The RESPO handshake will ensure continuity of revenue streams funding N-Tidal, protection against counterfeit consumables and allow for differential pricing by cardio-respiratory condition and geographic market.** It is a critical component for the successful commercialisation of the N-Tidal.This Innovate UK funded research will complete the digital health infrastructure, enabling CRiL's N-Tidal personal respiratory monitor to transform the management of respiratory conditions in the UK and internationally."

“一种低成本的个人医疗设备有很大的市场机会，患者可以使用这种设备来帮助监测和管理他们的呼吸状况。仅在英国，就有超过80万慢性阻塞性肺疾病(COPD)患者，以及540万哮喘患者。世卫组织估计，在全球范围内，有100万慢性阻塞性肺病患者和3.35亿哮喘患者。**人们普遍认为，由于缺乏有效的个人监测仪，*以方便和经济高效的方式测量肺功能，因此许多呼吸系统状况管理不善。**这会导致高度的呼吸恶化，有时会导致永久性的肺损伤，并经常导致本可避免的高昂住院费用。斯波西剑桥郡的剑桥呼吸创新有限公司(CRIL)发现，患者和医疗保健专业人员对“联网”个人呼吸监测仪的需求显然没有得到满足。医生、呼吸护士和患者对目前的设备不满意，这些设备是峰值流量计和肺活量计(这两种仪器都需要用力呼气动作，而且依赖于技术)。**CRIL开发了N-潮汐呼吸管理系统，该系统基于测量正常潮气呼吸中的二氧化碳。在N-TideB个人呼吸监测器的推动下，N-Tdal最终将促进对COPD、哮喘和其他慢性呼吸道疾病的正确诊断和监测。**Innovate UK正在资助研究，这将：1.创建主要的N-Tdal患者数据库，具有适当的N3/HIPAA安全通信。在中央N型潮汐数据库和RESPO(可更换封闭式传感器配对光纤)之间创建安全的“握手”，RESPO是一种智能的N型潮汐消耗品，对测量TBCO2波形至关重要。确保N潮数据和警报的完整性。**RESPO握手是此项目中最具创新性的元素。**它是N潮B的基本组件。RESPO是一种基于时间的消耗品，它将是可处方的，并将为N潮提供收入来源。它的使用将把患者、设备和数据库联系起来，验证数据分析和时间段是否得到了资金支持。**RESPO握手将确保为N-Tdal提供资金的收入来源的连续性，防止假冒耗材，并允许根据心肺状况和地理市场的不同而进行不同的定价。**这是N-Tidal成功商业化的关键组成部分。这项由英国创新资助的研究将完成数字健康基础设施，使CRIL的N-Tida个人呼吸监测仪能够改变英国和国际上对呼吸状况的管理。“