Development of an innovative biocompatible hip resurfacing system

该项目的首要目标是为髋关节表面置换适应症开发一种创新的解决方案。目前可用于髋关节表面置换的解决方案已受到患者不良结果的影响，特别是由于与这些设备的金属对金属结构和金属颗粒释放有关的问题。因此，我们的目标是开发一种先进的表面处理系统(PolyMotion)，该系统将提供独特的生物兼容性轴承和卓越的磨损性能，而不存在与传统轴承产品相关的风险。聚乙烯材料技术的最新进展，加上令人鼓舞的中期临床结果，为JointMedica(JM)提供了一种生物兼容的低风险替代金属对金属的方法，预计这种方法将提供低不良反应风险，同时具有优异的性能和更低的磨损。全髋关节置换术在老年和相对不活跃的患者中相当成功。然而，在更年轻、更活跃的患者中，人工髋关节很快就会磨损，导致不可避免的、昂贵的翻修手术和相关的并发症。这里提出的创新解决方案的开发将提供比传统髋关节置换更好的稳定性、寿命和更高水平的患者活动，恢复受影响患者的生活质量，并降低医疗成本。

The overarching objective of this project is to develop an innovative solution for hip resurfacing indications. Current solutions available for hip resurfacing have been marred by poor results in patients, especially due to issues related to the metal-on-metal construction of these devices and the release of metal particles. The aim is therefore to develop an advanced resurfacing system (Polymotion) that will provide a unique biocompatible bearing and superior wear performance without the risks associated with conventional bearing offerings. Recent advances in polyethylene material technology, coupled with encouraging mid-term clinical results, offer Jointmedica (JM) a biocompatible low-risk alternative to metal-on-metal, which is expected to offer a low adverse reaction risk coupled with superior performance and lower wear. Total hip replacement procedures are reasonably successful in elderly and relatively inactive patients. However, replacement hip joints wear out quickly in younger, more active patients, leading to an inevitable and costly revision surgery and associated complications. Development of the innovative solution proposed herein will provide better stability, longevity and higher levels of patient activity than traditional hip replacement, restoring the quality of life of those affected and reducing healthcare costs.