Development of a small, low-cost, accurate and rapid Point-of-Care diagnostic platform, with primary application to critical cardiovascular markers

开发小型、低成本、准确、快速的护理点诊断平台，主要应用于关键心血管标志物

• 批准号: 104463
• 金额: $ 121.71万
• 依托单位: OSLER DIAGNOSTICS LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=104463
• 关键词: Development; small; low; cost; accurate

"We are developing the next generation of healthcare diagnostics. Our portable diagnostic device could be deployed in the hospital emergency department, ambulance, or doctor's office and be used to diagnose diseases in under 10 minutes, cheaply, accurately, and from a pinprick of blood; moreover, it could diagnose an ever-increasing range of diseases, and multiple diseases simultaneously. In its first application, our device will be applied to critical cardiovascular diseases, including heart attack (myocardial infarction), acute coronary syndrome, heart failure, and pulmonary embolism/deep vein thrombosis.No longer will patients require unpleasant large blood samples, long, nervous waits for results, or the risk of serious deterioration whilst testing is still underway; instead, testing will be quick and simple, allowing more rapid treatment decisions. It will also result in significant savings for the NHS.The technology behind our device is novel to diagnostics (hence the dramatic improvement in capabilities) and has been developed over the past decade at the University of Oxford. Moreover, it has already been proven to work in feasibility studies on real patient samples. We are now perfecting the technology and translating it to a handheld automatic device to be deployed in healthcare settings.We are also actively engaging all stakeholders of the healthcare system, including end-users, to ensure a quick go-to-market, and seamless integration into patient pathways."

“我们正在开发下一代医疗诊断。我们的便携式诊断设备可以部署在医院急诊室，救护车或医生办公室，并用于在10分钟内诊断疾病，廉价，准确，从一个针刺的血液;此外，它可以诊断越来越多的疾病，并同时诊断多种疾病。在其首次应用中，我们的设备将应用于包括心脏病发作在内的严重心血管疾病（心肌梗死）、急性冠脉综合征、心力衰竭和肺栓塞/深静脉血栓形成。患者不再需要令人不快的大量血液样本，不再需要长时间紧张等待结果，也不再需要在检测仍在进行时有严重恶化的风险;相反，检测将是快速和简单的，从而能够更迅速地作出治疗决定。这也将为NHS节省大量资金。我们的设备背后的技术对于诊断来说是新颖的（因此能力得到了极大的提高），并且在过去的十年中在牛津大学得到了发展。此外，它已经被证明在真实的患者样本的可行性研究中有效。我们正在完善这项技术，并将其转化为手持式自动设备，用于医疗保健环境。我们还积极与医疗保健系统的所有利益相关者（包括最终用户）合作，以确保快速上市，并无缝集成到患者路径中。"