CERVICAL ABNORMALITIES AND SMOKING

广泛的流行病学证据现在支持两者之间的因果联系 吸烟和宫颈癌。此外，可替宁在食品中的检测 吸烟者的宫颈粘液表明生物学上可信的联系 吸烟和早期宫颈异常。年度常规妇科 考试提供了一个机会：提供与吸烟有关的信息 对生殖健康的影响，增强戒烟的动力 并增加育龄妇女停止生育的可能性。 建议进行一项随机试验，以评估最先进的吸烟 作为帕金森病常规随访的一部分提供戒烟干预 与通常的护理相比，检查可以提高戒断率。一秒钟 目的是评估异常检测结果的通知是否 增强戒烟的动力和可能性。 这项研究将在普吉特湾的团体健康合作社进行。 将对自动宫颈细胞学数据库进行审查，以确定 最近的帕普放映。700名吸烟者(350名测试正常) 结果和350个正常结果)将通过 以人口为基础的妇女健康电话调查。吸烟者将会是 根据巴氏试验结果分层并随机进行两种干预之一 情况：第1组，常规护理或第2组，励志自助 附属品。随机分为第一组的吸烟者将得到通常的标准 提供者形式的护理：吸烟状况评估，戒烟建议 吸烟，转介到可获得的戒烟帮助，以及 关于吸烟和总体情况的宣传/激励小册子 生殖健康。被分配到第二组的吸烟者将获得自助 小册子，书面的个性化反馈和3个来自 戒烟顾问。戒烟结果包括以下阶段 戒烟、戒烟动机的水平和类型、最初戒烟 并在基线、6个月和15个月时获得持续戒断 后续电话调查。 该项目的首要目标是确定有效的癌症。 针对健康女性吸烟者的预防干预策略。

Extensive epidemiologic evidence now supports a causal association between smoking and cervical cancer. Moreover, detection of cotinine in the cervical mucus of smokers suggests a biologically plausible link between smoking and early cervical abnormalities. Annual routine gynecological exams represent an opportunity to: provide information which links smoking to reproductive health outcomes, enhance motivation for smoking cessation and increase the likelihood of cessation in reproductive age women. Proposed is a randomized trial to assess whether state-of-the-art smoking cessation interventions provided as part of routine follow-up for Pap exams can increase cessation rates relative to usual care. A second objective is to assess whether notification of abnormal test results enhances motivation for and likelihood of smoking cessation. The research will be conducted at Group Health Cooperative of Puget Sound. An automated cervical cytology database will be reviewed to identify recent Pap screenees. A cohort of 700 smokers (350 with normal test results and 350 with a normal results) will be identified through a population based women's health telephone survey. Smokers will be stratified on Pap test result and randomized to one of two intervention conditions: Group 1, usual care or Group 2, self-help with motivational adjuncts. Smokers randomized to Group 1 will receive the usual standard care in the form of provider: assessment of smoking status, advice to quit smoking, referral to available assistance for smoking cessation, and an informational/motivational pamphlet regarding smoking and overall reproductive health. Smokers assigned to Group 2 will receive a self-help booklet, written personalized feedback and 3 telephone calls from a cessation counselor. Smoking cessation outcomes including stage of cessation, level and type of motivation to quit smoking, initial cessation and sustained abstinence will be obtained at baseline, 6 and 15 month follow-up telephone surveys. The overarching goal of the project is to identify effective cancer prevention intervention strategies for healthy women smokers.