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LIPOPHILIC CALCIUM FLUOROIONOPHORES

LIPOPHILIC CALCIUM FLUOROIONOPHORES
亲脂性钙氟离子载体
批准号:
2188566
负责人:
MARGARET E LANGMUIR
金额:
$7.5万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-12-01 至 1994-11-30

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中文摘要
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英文摘要
We propose to synthesize and test new lipophilic fluorescent ionophores for measuring calcium ion concentrations in aqueous solutions. The ionophores are designed to be soluble in synthetic membranes and to respond selectively to Ca2+ in a contacting aqueous solution by undergoing a shift in absorption and emission to longer wavelengths. The proposed compounds will be of primary interest for incorporating into a fiber optic chemical sensor (FOCS). A FOCS device will be of use for determining the concentration of calcium ion in biological fluids in vitro and ultimately in vivo. A device based on this design would be valuable in the intensive care unit or other hospital facility.
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PHOTOSTABLE FLUORESCENT DYES FOR BIOCHEMISTRY/MICROSCOPY
  • 批准号:
    2193265
  • 项目类别:
  • 资助金额:
    $10.0万
  • 财政年份:
    1996
  • 负责人:
    MARGARET E LANGMUIR
  • 依托单位:
PHOTOSTABLE FLUORESCENT DYES FOR BIOCHEM/MICROSCOPY
  • 批准号:
    2539817
  • 项目类别:
  • 资助金额:
    $37.55万
  • 财政年份:
    1996
  • 负责人:
    MARGARET E LANGMUIR
  • 依托单位:
NEW FLUORESCENT THIOL PROBES FOR FLOW CYTOMETRY AND PCR
  • 批准号:
    2097808
  • 项目类别:
  • 资助金额:
    $26.19万
  • 财政年份:
    1994
  • 负责人:
    MARGARET E LANGMUIR
  • 依托单位:
GSH RECEPTOR PROBES TO STUDY CNS DEVELOPMENT/DYSFUNCTION
  • 批准号:
    2270259
  • 项目类别:
  • 资助金额:
    $38.79万
  • 财政年份:
    1994
  • 负责人:
    MARGARET E LANGMUIR
  • 依托单位:
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