GROWTH AND HEALTH STUDY

生长与健康研究

• 批准号: 2225055
• 负责人: Z I SABRY
• 金额: $ 60.62万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-04-01 至 1999-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2225055
• 关键词: African American; adolescence (12-20); blood lipid; body composition; body physical activity; body physical characteristic; cardiovascular disorder epidemiology; caucasian American; cooperative study; depression; diet; disease /disorder proneness /risk; female; glucose; health behavior; human subject; hypertension; insulin; longitudinal human study; nutrition related tag; obesity; racial /ethnic difference; self concept; socioeconomics; stress; women's health

The NHLBI Growth & Health Study Exension (NGHS III) will continue to follow a cohort of 2,379 black and white girls first measured in 1987 when they were 9 nd 10 years old. The primary research goals continue to be the investigation of the antecedent of the differential development of obesity in black and white adolescent females and the determination of the degree to which differences in the development of obesity are associated with differences in other coronary vascular disease risk factors, such as blood pressure, blood lipids/lipoproteins and apolipoproteins. The study has tracked the girls through earl and mid-adolescence; a five year extension is proposed to continue examinations through that stage of late adolescence when patterns of adult womanhood become established. Attention will be directed toward dietary habits, physical activity patterns, socioeconomic status, psychosocial and cultural factors, early pregnancy, and lifestyle changes and choices. The Study will assess: (1) anthropometric parameters reflecting obesity and distribution of body fat, (2) changes in dietary intake and physical activity, (3) psychosocial measures of self-esteem, stress, health perceptions, depression and hopelessness, (4) blood pressure, blood lipids, glucose and insulin, and (5) demographic factors. The Berkeley clinical center, currently seeing approximately 85% of its original enrollees, proposes to increase its rate of cohort compliance by traveling to see those girls who have moved to ares outside the study area. As in the pst, local girls will continue to be seen either at their homes or at a local hospital site. The existent detailed research protocol and the ongoing trained and certified staff of medical examiners and interviewers will ensure high quality data collection. The Study will continue to yield important scientific information to help clarify etiology of the higher incidence of obesity and hypertension in black adolescent girls, track the development of the risk factors associated with CVD mortality in black women, and identify the interrelationship of these factors, ultimately promoting effective interventions in women's health.

NHLBI增长与健康研究扩展（NGHS III）将继续进行 1987年，一组2,379名黑人和白色女孩首次被测量， 分别是9岁和10岁。 主要研究目标仍然是 肥胖差异发展的前因研究 在黑人和白色青少年女性中， 肥胖发展的差异与 其他冠状动脉疾病危险因素的差异，如血液 血压、血脂/脂蛋白和载脂蛋白。 这项研究跟踪了这些女孩从青春期到青春期中期的整个过程， 建议延长一年，以便在这一阶段继续进行考试， 青春期后期，这时成年女性的模式已经形成。 注意力将被引导到饮食习惯，体育活动 模式，社会经济地位，心理和文化因素，早期 怀孕，生活方式的改变和选择。 研究将评估：（1） 反映肥胖和身体脂肪分布的人体测量参数， (2)饮食摄入量和体力活动的变化，（3）心理社会 自尊、压力、健康观念、抑郁和 绝望，（4）血压、血脂、血糖和胰岛素，以及 (5)人口因素。 伯克利临床中心，目前看到大约85%的 原始登记者，建议通过以下方式提高其队列依从率： 去看望那些搬到研究区以外的战神的女孩。 与PST一样，当地女孩将继续在家中或家中被看到 或在当地医院现场。 现有的详细研究方案和 不断培训和认证的体检医师工作人员， 访谈员将确保高质量的数据收集。 这项研究将 继续产生重要的科学信息，以帮助澄清病因 黑人青少年肥胖和高血压的发病率较高， 女孩，跟踪与CVD相关的风险因素的发展 黑人妇女的死亡率，并确定这些之间的相互关系， 这些因素，最终促进对妇女健康的有效干预。