GERIATRIC PHARMACOEPIDEMIOLOGY

开展药物流行病学研究需要了解 药理学、老年医学和流行病学。 罗纳德肖博士是一位 委员会认证的内科医生和老年病学家， 药理学和药物流行病学。他最近完成了MS。在 流行病学，并被选为第一个汽巴-嘉基研究员， 范德比尔特的药物流行病学。NIA学术奖将 提供额外五年的受保护研究， 调查员在这个领域。 肖尔博士会在前两个月 年的拟议NIA学术奖进行人口为基础的 个体磺脲类药物和风险的回顾性队列研究 使用田纳西州医疗补助的老年人中的严重低血糖 数据库他将逐渐认识到 药物流行病学研究的自动化数据库，并将获得 独立进行未来调查所需的技能。博士 Shorr还将参加一项教育干预研究， 减少长期护理环境中抗精神病药物的使用。这一领域 长期护理研究将补充数据库调查， 给Shorr博士一个机会，在一个 正在进行的大规模调查。 学术奖的最后三年将用于 进一步的数据库和/或实地项目。 一个潜在的项目是 口服抗凝剂的出血并发症调查 使用医疗补助或其他自动化数据库的老年人。 是 预计这种集中的研究经验将使他能够 在这一至关重要的学科中进行独立调查。 博士Shorr还将在内政部任职 在范德比尔特当医生。 他将与另外两名老年病学家一起， 不断发展的临床项目的核心 因此，他将拥有 向医学生和住院工作人员教授老年医学的机会 无论是住院还是门诊。 他还将在以下方面发挥作用： 老年医学基础与临床教学课程建设 在范德比尔特继续扩大。 这些活动将加强 预防医学系的研究项目， Shorr博士未来在老年医学领域的领导作用 药

Conducting pharmacoepidemiologic research requires knowledge of pharmacology, geriatric medicine and epidemiology. Dr. Ronald Shorr is a board certified internist and geriatrician who has research experience in pharmacology and pharmacoepidemiology. He has recently completed a M.S. in epidemiology and was chosen as the first Ciba-Geigy Fellow in Pharmacoepidemiology at Vanderbilt. The proposed NIA Academic Award will provide five additional years of protected research with established investigators in this field. Dr. Shorr will spend most of the first two years of the proposed NIA Academic Award conducting a population-based retrospective cohort study of individual sulfonylureas and the risk of serious hypoglycemia in elderly persons using the Tennessee Medicaid database. He will develop an awareness of the strengths and limitations of automated databases for pharmacoepidemiologic research, and will acquire the skills necessary to conduct future investigations independently. Dr. Shorr will also participate in a study of an educational intervention to reduce antipsychotic drug use in long term care settings. This field research in long term care will compliment the database investigation and give Dr. Shorr an opportunity to function as a clinical collaborator in an ongoing large-scale investigation. The final three years of the proposed Academic Award will be spent on further database and/or field projects. A potential project is the investigation of hemorrhagic complications of oral anticoagulants in elderly persons using the Medicaid or other automated database. It is anticipated that this focused research experience will enable him to conduct independent investigations in this vitally important discipline. Dr. Shorr will also have an appointment in the Department of Internal Medicine at Vanderbilt. He will join two other geriatricians to form the nucleus of a growing clinical program. As such, he will have the opportunity to teach geriatric medicine to medical students and house staff in both inpatient and ambulatory settings. He will also play a role in curriculum development as preclinical and clinical teaching of geriatrics at Vanderbilt continues to expand. These activities will augment the research program in the Department of Preventive Medicine towards the preparation of Dr. Shorr for a future leadership role in geriatric medicine.