GERIATRIC PHARMACOEPIDEMIOLOGY

进行药物流行病学研究需要了解 药理学、老年医学和流行病学。罗纳德·肖尔博士是一位 具有以下研究经验的董事会认证内科医生和老年医生 药理学和药物流行病学。他最近完成了理科硕士学位。 并被选为#年第一个Ciba-Geigy研究员 范德比尔特的药物流行病学。拟议的NIA学术奖将 提供额外五年的受保护研究，并建立 这一领域的调查人员。肖尔博士将在前两年的大部分时间里 几年来，NIA拟议的学术奖进行了一项基于人口的 磺脲类药物个体及其风险的回顾性队列研究 使用田纳西州医疗补助计划的老年人发生严重低血糖 数据库。他将逐渐认识到 用于药物流行病学研究的自动化数据库，并将获得 独立开展未来调查所需的技能。Dr。 Shorr还将参与一项教育干预研究，以 减少长期护理环境中抗精神病药物的使用。此字段 长期护理研究将补充数据库调查和 让Shorr医生有机会在 正在进行大规模调查。 拟议学术奖的最后三年将用于 进一步的数据库和/或实地项目。一个潜在的项目是 门诊患者口服抗凝剂出血性并发症的调查 使用医疗补助或其他自动数据库的老年人。它是 预计这种专注的研究经验将使他能够 在这一极其重要的学科中进行独立调查。 肖尔博士还将在内务部有一个预约 范德比尔特的医学部。他将与另外两名老年病医生一起成立 一个不断发展的临床项目的核心。因此，他将拥有 向医学生和宿舍工作人员讲授老年医学的机会 在住院和门诊环境中都是如此。他还将在 老年医学基础与临床教学中的课程建设 在范德比尔特继续扩张。这些活动将增加 预防医学系的研究项目 Shorr博士为未来在老年病领域担任领导角色做好准备 医药。

Conducting pharmacoepidemiologic research requires knowledge of pharmacology, geriatric medicine and epidemiology. Dr. Ronald Shorr is a board certified internist and geriatrician who has research experience in pharmacology and pharmacoepidemiology. He has recently completed a M.S. in epidemiology and was chosen as the first Ciba-Geigy Fellow in Pharmacoepidemiology at Vanderbilt. The proposed NIA Academic Award will provide five additional years of protected research with established investigators in this field. Dr. Shorr will spend most of the first two years of the proposed NIA Academic Award conducting a population-based retrospective cohort study of individual sulfonylureas and the risk of serious hypoglycemia in elderly persons using the Tennessee Medicaid database. He will develop an awareness of the strengths and limitations of automated databases for pharmacoepidemiologic research, and will acquire the skills necessary to conduct future investigations independently. Dr. Shorr will also participate in a study of an educational intervention to reduce antipsychotic drug use in long term care settings. This field research in long term care will compliment the database investigation and give Dr. Shorr an opportunity to function as a clinical collaborator in an ongoing large-scale investigation. The final three years of the proposed Academic Award will be spent on further database and/or field projects. A potential project is the investigation of hemorrhagic complications of oral anticoagulants in elderly persons using the Medicaid or other automated database. It is anticipated that this focused research experience will enable him to conduct independent investigations in this vitally important discipline. Dr. Shorr will also have an appointment in the Department of Internal Medicine at Vanderbilt. He will join two other geriatricians to form the nucleus of a growing clinical program. As such, he will have the opportunity to teach geriatric medicine to medical students and house staff in both inpatient and ambulatory settings. He will also play a role in curriculum development as preclinical and clinical teaching of geriatrics at Vanderbilt continues to expand. These activities will augment the research program in the Department of Preventive Medicine towards the preparation of Dr. Shorr for a future leadership role in geriatric medicine.