The impact of environmental toxicants on the fertility of female animals

环境毒物对雌性动物生育能力的影响

• 批准号: DP200103408
• 负责人: Prof Karla Hutt
• 金额: $ 41.38万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200103408
• 关键词: impact; environmental; toxicants; fertility; female

This study aims to address a problem of national significance; determining the impact of commonly used environmental toxicants (pesticides) on the fertility and health of female animals, both agricultural and native. This project expects to generate new knowledge in the fields of ovarian biology, female fertility and toxicology by using a combination of mouse and marsupial animal models. The expected outcomes include the establishment of interdisciplinary collaborations and provision of world-class training for staff and students in the field of reproductive biology. This project should provide significant benefits, such as improved chemical management in livestock production and the development of marsupial conservation action plans.

本研究旨在解决一个具有国家意义的问题；确定常用环境毒物（杀虫剂）对雌性动物（包括农业动物和原生动物）的生育能力和健康的影响。该项目希望通过小鼠和有袋动物模型的结合，在卵巢生物学、女性生育和毒理学领域产生新的知识。预期的成果包括建立跨学科合作和为生殖生物学领域的工作人员和学生提供世界一流的培训。该项目将带来显著的效益，如改善畜牧业生产中的化学品管理和制定有袋动物保护行动计划。