NEW METHODS OF ANALYSIS FOR STIMULUS-DRIVEN EEG ACTIVITY

现有计划项目的总体目标（“CNS自适应 口面感觉的机制”）是（1）开发改进的方法 用于量化人类躯体感觉中的中枢适应 神经系统和（2）评估的假设，各种口面 感觉障碍（包括颞下颌关节紊乱病）部分涉及 动态神经机制的异常和适应不良功能 这有助于正常皮层适应维持躯体感觉 传入驱动 在此上下文中，作为此FIRCA的父项目的子项目 应用程序有其具体目标：（1）确定定量头皮 体感皮层适应的电生理（EEG）指标; (2)来详细描述他们在正常人中的行为 成年人;（3）利用它们进行直接的实验比较， 正常人和口面感觉神经病患者的适应性反应 紊乱 拟议的合作旨在补充实验性和 生理优势，现有的非常规的 实验室的一个研究小组的定量能力 华沙大学医学物理学专业， 先进信号处理技术的发展和应用 脑电图分析。 使用真实的和模拟的EEG数据，国外 合作者将以最佳形式开发、评估和实施， 母项目使用了几种新的分析方法， 将极大地促进其提取具有生物学意义的 从收集的数据中获取信息，从而相应地提高其 实现方案项目目标的能力， 从原计划中转移精力。

The overall goals of the existing program project ("CNS Adaptive Mechanisms in Orofacial Sensation") are (1) to develop improved methods for quantification of central adaptation in the human somatosensory nervous system and (2) to evaluate the hypothesis that various orofacial sensory disorders (including temporomandibular disorders) involve in part the abnormal and maladaptive functioning of dynamic neural mechanisms that subserve normal cortical adaptation to maintained somatosensory afferent drive. Within this context, the subproject that is the parent to this FIRCA application has as its specific aims: (1) to identify quantitative scalp electrophysiological (EEG) indices of somatosensory cortical adaptation; (2) to characterize in detail their behavior in a sample of normal adults; and (3) to utilize them for direct experimental comparison of adaptive responses in normals and in patients with orofacial sensory disorders. The proposed collaboration seeks to complement the experimental and physiological strengths of the existing UNC program with the unusual quantitative capabilities of a research group at the Laboratory of Medical Physics at the University of Warsaw which specializes in development and application of advanced signal-processing techniques for EEG analysis. Using both real and simulated EEG data, the foreign collaborators will develop, evaluate, and implement in optimal form for use by the parent project several novel analytical procedures which should greatly facilitate its ability to extract biologically significant information from the collected data, and thus enhance correspondingly its capacity to address program-project-objectives without significant diversion of effort from the original plan.