TREATMENT FOR DEPRESSED, SUBSTANCE ABUSING ADOLESCENTS

抑郁症、药物滥用青少年的治疗

• 批准号: 2121790
• 负责人: JOHN F CURRY
• 金额: $ 8.88万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-20 至 1997-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2121790
• 关键词: adolescence (12-20); cognitive behavior therapy; combination therapy; depression; family structure /dynamics; family therapy; group therapy; handbook; health care personnel education; human subject; human therapy evaluation; interview; literature survey; psychological tests; questionnaires; satisfaction; social behavior; substance abuse related disorder; therapy compliance; training; videotape /videodisc

Substance abuse is a major public health problem associated with destructive or life-threatening outcomes in adolescents. Many substance abusing adolescents present with one or more co-morbid mental disorders, of which one of the most common is depression. In developing effective psychosocial substance abuse treatments, therefore, it is necessary to address co-morbid disorders. Studies of social cognitive and family characteristics, prevention and treatment suggest that cognitive behavioral interventions may be effective in the treatment of depressed, substance abusing adolescents. The first specific aim of this project is to develop and to operationalize in manuals a combined Group Cognitive Behavior Therapy (GCBT) and Family Cognitive Behavior Therapy (FCBT) for depressed, substance abusing adolescents. The second aim is to demonstrate the feasibility of conducting combined GCBT and FCBT with these adolescents and to provide pilot data for a subsequent, controlled outcome study. The third aim is to demonstrate the feasibility of training substance abuse counselors and therapies in the use of this treatment. The forth aim is to evaluate change in substance abuse and depression during treatment. To accomplish these aims, a ten step sequence of manual development and pilot testing is proposed. In the first year, initial manuals will be developed, based on literature review and consultation. In the second year, the Principal Investigator and Co-Investigator will treat six cases, with videotape supervision and expert consultation. After further manual revision, substance abuse counselors and therapists will be trained in year two and will conduct supervised treatment of 12 cases in year three. Treatment will consist of 16 weeks of GCBT and FCBT. Diagnostic interviews and self-report measures will be completed before and after treatment. Data analyses will address treatment integrity, patient satisfaction, and changes in diagnostic status, self-reported substance abuse and depression, and social cognitive and family variables. To plan a subsequent outcome study, power analysis will be used. Pilot data will include patient characteristics, compliance, attendance, and attrition rates.

药物滥用是一个重大的公共卫生问题 对青少年造成破坏性或危及生命的后果。许多物质 虐待患有一种或多种共病精神障碍的青少年， 其中最常见的一种是抑郁症。在发展有效的 因此，有必要进行心理社会药物滥用治疗 解决共病疾病。社会认知和家庭研究 特征、预防和治疗表明认知 行为干预可能有效治疗抑郁症 滥用药物的青少年。该项目的第一个具体目标是 开发并在手册中实施组合的群体认知 行为治疗 (GCBT) 和家庭认知行为治疗 (FCBT) 抑郁、滥用药物的青少年。第二个目标是 论证联合进行 GCBT 和 FCBT 的可行性 这些青少年，并为随后的受控研究提供试点数据 结果研究。第三个目的是证明可行性 培训药物滥用顾问和治疗人员使用此方法 治疗。第四个目标是评估药物滥用的变化和 治疗期间出现抑郁症。 为了实现这些目标，需要进行十个步骤的手动开发和 建议进行试点测试。在第一年，初始手册将是 是在文献综述和咨询的基础上制定的。在第二个 年，首席研究员和联合研究员将治疗六名 案件进行录像监督、专家会诊。进一步之后 手动修订，药物滥用咨询师和治疗师将 第二年接受培训，并将在监督下治疗 12 例病例 第三年。治疗包括 16 周的 GCBT 和 FCBT。 诊断访谈和自我报告措施将在之前完成 以及治疗后。数据分析将解决治疗的完整性， 患者满意度以及诊断状态的变化，自我报告 药物滥用和抑郁，以及社会认知和家庭 变量。为了计划后续的结果研究，将进行功效分析 用过的。试点数据将包括患者特征、依从性、 出勤率和流失率。